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公开(公告)号：WO2004110173A1
公开(公告)日：2004-12-23
申请号：PCT/US2004/019655
申请日：2004-06-16
Applicant: ABBOTT LABORATORIES , NDIFE, Louis, I. , LUCAS, Booker, T., III , OSTROM, Karin, M.
Inventor： NDIFE, Louis, I. , LUCAS, Booker, T., III , OSTROM, Karin, M.
IPC: A23L1/29
CPC classification number: A61K36/48 , A23L11/07 , A23L33/105 , A23L33/185 , A23L33/21 , A23L33/40 , A61K2300/00
Abstract: Disclosed are fiber-containing nutritional powders comprising nutrients and a total dietary fiber component, wherein the total dietary fiber contains added, spray dried, fiber, and wherein at least about 50% by weight of the spray dried fiber is water insoluble. Also disclosed are improved methods of making nutritional powders by (A) preparing an aqueous liquid containing nutrients and added fiber, wherein at least about 50% by weight of the added fiber is water insoluble; (B) homogenizing the prepared aqueous liquid at a selected homogenization pressure; and (C) spray drying the homogenized liquid to form a nutritional powder, which can be formulated or reconstituted into a nutritional liquid. The nutritional formula is more effective than conventional fiber-containing, ready-to-feed, nutritional liquids in treating infants affected by colic, diarrhea, or excessive spit-up.
Abstract translation: 公开了包含营养物和总膳食纤维组分的含纤维营养粉末，其中总膳食纤维含有加入的喷雾干燥的纤维，并且其中至少约50重量％的喷雾干燥纤维是水不溶性的。 还公开了通过（A）制备含有营养物和加入的纤维的含水液体制备营养粉末的改进方法，其中至少约50重量％的加入的纤维是水不溶性的; （B）在选择的均化压力下均化所制备的水性液体; 和（C）喷雾干燥均匀的液体以形成营养粉末，其可以配制或重构成营养液体。 营养配方比常规含纤维，即食食品，营养液在治疗由腹痛，腹泻或过度吐血影响的婴儿更有效。
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公开(公告)号：WO2005018343A1
公开(公告)日：2005-03-03
申请号：PCT/US2004/025162
申请日：2004-08-04
Applicant: ABBOTT LABORATORIES , CHMURA, James, N. , CIPOLLO, Kent, L. , NDIFE, Louis, I. , OSTROM, Karin, M.
Inventor： CHMURA, James, N. , CIPOLLO, Kent, L. , NDIFE, Louis, I. , OSTROM, Karin, M.
IPC: A23L1/305
CPC classification number: A23L2/52 , A23L33/16 , A23L33/185 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/5488 , A23V2250/1578
Abstract: Disclosed are calcium fortified, soy-based, infant nutritional formulas, including powder, liquid, or concentrate embodiments comprising per 100 kcal of formula (A) lipid, preferably up to about 8.0 g, (B) carbohydrate, preferably from about 8.0 g to about 16.0 g, (C) phytase-treated soy protein, preferably up to about 3.5 g and (D) calcium, preferably up to about 90 mg of calcium; wherein the nutritional formula is an infant formula having a calcium to lipid weight ratio of from about 0.002 to about 0.020, and wherein the formula contains not more than about 8.4 mg phytic acid per 100 kcal of formula. It has been found that these calcium-fortified, phytase-treated, soy-based, nutritional formulas provide for softer stools in infant populations, especially as compared to infants fed with other soy-based formulas including commercial soy formulas as well as soy based formulas derived from dephytinization methods other than phytase treatment, e.g., ion exchange.
Abstract translation: 公开了钙强化的大豆基的婴儿营养配方，包括粉末，液体或浓缩物实施方案，其包含每100千卡的式（A）脂质，优选至多约8.0克，（B）碳水化合物，优选约8.0克至 约16.0g，（C）植酸酶处理的大豆蛋白，优选至多约3.5g和（D）钙，优选至多约90mg的钙; 其中所述营养配方是具有约0.002至约0.020的钙与脂质重量比的婴儿配方，并且其中所述配方包含不超过约8.4mg植酸/ 100kcal配方。 已经发现，这些钙强化的，植酸酶处理的大豆基营养配方提供了婴儿群体中较软的粪便，特别是与喂养其它大豆基配方的婴儿相比，其中包括商业大豆配方以及大豆基配方 衍生自植酸酶处理以外的脱氢方法，例如离子交换。
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3.发明申请
公开(公告)号：WO1998010665A1
公开(公告)日：1998-03-19
申请号：PCT/US1997016081
申请日：1997-09-11
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , SUH, John, D. , OSTROM, Karin, M. , NDIFE, Louis, I. , ANLOAGUE, Paul, S. , CHURMA, James, N. , DAAB-KRZYKOWSKI, Andre , JOHNS, Paul, W. , GARCIA, Diane, M. , MAZER, Terrence, B. , MEI, Fu-I
IPC: A23J03/14
Abstract: The present invention relates generally to a process of isolating isoflavones/phytoestrogens from a plant protein and producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese and/or nucleotides. More specifically, this invention is directed to a process of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. Either the removed phytoestrogens or the treated plant protein may be retained for further processing. The phytoestrogens have utility as pharmaceuticals. The treated plant protein has utility in nutritional products. This invention is also directed to isoflavones prepared by the process, to plant protein products resulting from the inventive process, and to nutritional products that use the plant protein product as a source of amino nitrogen.
Abstract translation: 本发明一般涉及从植物蛋白中分离异黄酮/植物雌激素并产生植物蛋白的方法，所述植物蛋白用于具有降低的植物雌激素，锰和/或核苷酸水平的营养产品。 更具体地，本发明涉及使用离子交换技术从植物蛋白中去除植物雌激素，锰或核苷酸的方法。 被去除的植物雌激素或经处理的植物蛋白质可被保留用于进一步处理。 植物雌激素作为药物具有实用性。 经处理的植物蛋白质可用于营养产品。 本发明还涉及通过该方法制备的异黄酮，用于植入由本发明方法产生的蛋白质产物，以及使用植物蛋白产物作为氨基氮源的营养产品。
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Patent Agency Ranking
公开(公告)号：EP1656039B1
公开(公告)日：2007-02-21
申请号：EP04780063.6
申请日：2004-08-04
Applicant: ABBOTT LABORATORIES
Inventor： CHMURA, James, N. , CIPOLLO, Kent, L. , NDIFE, Louis, I. , OSTROM, Karin, M.
CPC classification number: A23L2/52 , A23L33/16 , A23L33/185 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/5488 , A23V2250/1578
Abstract: Disclosed are calcium fortified, soy-based, infant nutritional formulas, including powder, liquid, or concentrate embodiments comprising per 100 kcal of formula (A) lipid, preferably up to about 8.0 g, (B) carbohydrate, preferably from about 8.0 g to about 16.0 g, (C) phytase-treated soy protein, preferably up to about 3.5 g and (D) calcium, preferably up to about 90 mg of calcium; wherein the nutritional formula is an infant formula having a calcium to lipid weight ratio of from about 0.002 to about 0.020, and wherein the formula contains not more than about 8.4 mg phytic acid per 100 kcal of formula. It has been found that these calcium-fortified, phytase-treated, soy-based, nutritional formulas provide for softer stools in infant populations, especially as compared to infants fed with other soy-based formulas including commercial soy formulas as well as soy based formulas derived from dephytinization methods other than phytase treatment, e.g., ion exchange.
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公开(公告)号：EP1656039A1
公开(公告)日：2006-05-17
申请号：EP04780063.6
申请日：2004-08-04
Applicant: ABBOTT LABORATORIES
Inventor： CHMURA, James, N. , CIPOLLO, Kent, L. , NDIFE, Louis, I. , OSTROM, Karin, M.
CPC classification number: A23L2/52 , A23L33/16 , A23L33/185 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/5488 , A23V2250/1578
Abstract: Disclosed are calcium fortified, soy-based, infant nutritional formulas, including powder, liquid, or concentrate embodiments comprising per 100 kcal of formula (A) lipid, preferably up to about 8.0 g, (B) carbohydrate, preferably from about 8.0 g to about 16.0 g, (C) phytase-treated soy protein, preferably up to about 3.5 g and (D) calcium, preferably up to about 90 mg of calcium; wherein the nutritional formula is an infant formula having a calcium to lipid weight ratio of from about 0.002 to about 0.020, and wherein the formula contains not more than about 8.4 mg phytic acid per 100 kcal of formula. It has been found that these calcium-fortified, phytase-treated, soy-based, nutritional formulas provide for softer stools in infant populations, especially as compared to infants fed with other soy-based formulas including commercial soy formulas as well as soy based formulas derived from dephytinization methods other than phytase treatment, e.g., ion exchange.
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6.发明公开
公开(公告)号：EP0966210A1
公开(公告)日：1999-12-29
申请号：EP98911619.0
申请日：1998-03-12
Applicant: Abbott Laboratories
Inventor： BERK, David, F. , BREEN, Merlin, D. , CHMURA, James, N. , HUSTON, Todd, A. , MALONE, William, T. , OSTROM, Karin, M.
CPC classification number: A23L33/21 , A23L33/16 , A23L33/17 , A23L33/40 , A23V2002/00 , A23V2250/5488 , A23V2250/54246 , A23V2250/54252 , A23V2250/51082 , A23V2250/5028 , A23V2250/50722 , A23V2250/506 , A23V2250/50724
Abstract: The use of fiber to control infantile colic and diarrhea and adult constipation and diarrhea is well accepted. This invention is specifically directed to liquid nutritional formulas which contain hydrolyzed protein and/or amino acids and dietary fiber. This invention overcomes the problems of product physical stability and high viscosities through the use of soluble/non-fermentable fibers in combination with a blend of insoluble/non-fermentable and soluble/fermentable fibers. The invention is also directed to the use of physiologically effective levels of fibers in nutritional products that use hydrolyzed protein and/or free amino acids for the source of amino nitrogen to treat colic, diarrhea, short gut syndrome and other gastrointestinal maladies.
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公开(公告)号：EP1656039B2
公开(公告)日：2011-03-09
申请号：EP04780063.6
申请日：2004-08-04
Applicant: ABBOTT LABORATORIES
Inventor： CHMURA, James, N. , CIPOLLO, Kent, L. , NDIFE, Louis, I. , OSTROM, Karin, M.
CPC classification number: A23L2/52 , A23L33/16 , A23L33/185 , A23L33/40 , A23V2002/00 , Y10S426/801 , A23V2250/5488 , A23V2250/1578
Abstract: Disclosed are calcium fortified, soy-based, infant nutritional formulas, including powder, liquid, or concentrate embodiments comprising per 100 kcal of formula (A) lipid, preferably up to about 8.0 g, (B) carbohydrate, preferably from about 8.0 g to about 16.0 g, (C) phytase-treated soy protein, preferably up to about 3.5 g and (D) calcium, preferably up to about 90 mg of calcium; wherein the nutritional formula is an infant formula having a calcium to lipid weight ratio of from about 0.002 to about 0.020, and wherein the formula contains not more than about 8.4 mg phytic acid per 100 kcal of formula. It has been found that these calcium-fortified, phytase-treated, soy-based, nutritional formulas provide for softer stools in infant populations, especially as compared to infants fed with other soy-based formulas including commercial soy formulas as well as soy based formulas derived from dephytinization methods other than phytase treatment, e.g., ion exchange.
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8.发明公开PROCESS FOR TREATING PLANT PROTEINS AND NUTRITIONAL PRODUCTS MADE THEREFROM 无效VERFHAREN用于治疗PLANZLICHEM蛋白和由其制成的营养产品
公开(公告)号：EP0929231A1
公开(公告)日：1999-07-21
申请号：EP97941521.0
申请日：1997-09-11
Applicant: Abbott Laboratories
Inventor： SUH, John, D. , OSTROM, Karin, M. , NDIFE, Louis, I. , ANLOAGUE, Paul, S. , CHURMA, James, N. , DAAB-KRZYKOWSKI, Andre , JOHNS, Paul, W. , GARCIA, Diane, M. , MAZER, Terrence, B. , MEI, Fu-I
Abstract: The present invention relates generally to a process of isolating isoflavones/phytoestrogens from a plant protein and producing plant proteins for use in nutritional products that have reduced levels of phytoestrogens, manganese and/or nucleotides. More specifically, this invention is directed to a process of using ion exchange technology to remove phytoestrogens, manganese or nucleotides from plant proteins. Either the removed phytoestrogens or the treated plant protein may be retained for further processing. The phytoestrogens have utility as pharmaceuticals. The treated plant protein has utility in nutritional products. This invention is also directed to isoflavones prepared by the process, to plant protein products resulting from the inventive process, and to nutritional products that use the plant protein product as a source of amino nitrogen.
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