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1.发明申请DETECTION OF DIFFERENT HIV GENOTYPES UTILIZING A SYNTHETIC PEPTIDE-MODIFIED IMMUNOASSAY 审中-公开使用合成肽修饰的免疫球蛋白检测不同的HIV基因组
公开(公告)号：WO1995033206A1
公开(公告)日：1995-12-07
申请号：PCT/US1995004421
申请日：1995-04-10
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
IPC: G01N33/569
CPC classification number: C07K14/005 , C07K2319/00 , C12N2740/16122 , G01N33/56988
Abstract: An assay to simultaneously detect the presence of one or more HIV subtypes of HIV-1 antibody and/or HIV-2 antibody in a test sample is disclosed. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by using a cocktail of synthetic and recombinant antigen-containing indicator reagents. Preferred indicator reagents include a synthetic19 amino acid cyclic peptide homologous to an immunodominant region of HIV-1 gp 41 and a synthetic19 amino acid cyclic peptide homologous to an immunodominant region of HIV-2 gp 36.
Abstract translation: 公开了一种在测试样品中同时检测HIV-1抗体和/或HIV-2抗体的一种或多种HIV亚型的存在的测定法。 分析物被捕获在相同或不同的固相上，并且通过检测通过使用含有合成和重组抗原的指示剂试剂的混合物产生的信号来确定分析物的存在。 优选的指示剂包括与HIV-1 gp 41的免疫显性区域同源的合成的19个氨基酸的环肽和与HIV-2 gp 36的免疫显性区域同源的合成的19个氨基酸的环肽。
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Patent Agency Ranking2.发明申请HIV IMMUNOASSAY UTILIZING RECOMBINANT PROTEIN AND SYNTHETIC PEPTIDE REAGENTS 审中-公开艾滋病毒免疫应用重组蛋白和合成肽试剂
公开(公告)号：WO1995023973A2
公开(公告)日：1995-09-08
申请号：PCT/US1995002195
申请日：1995-02-21
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
IPC: G01N33/569
CPC classification number: G01N33/56988 , G01N33/68
Abstract: An assay to simultaneously detect the presence of HIV-1 antibody and/or HIV-2 antibody in a test sample is disclosed. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by using a cocktail of synthetic and recombinant antigen-containing indicator reagents.
Abstract translation: 公开了一种在测试样品中同时检测HIV-1抗体和/或HIV-2抗体的存在的测定法。 分析物被捕获在相同或不同的固相上，并且通过检测通过使用含有合成和重组抗原的指示剂试剂的混合物产生的信号来确定分析物的存在。
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公开(公告)号：WO1993021346A1
公开(公告)日：1993-10-28
申请号：PCT/US1993003224
申请日：1993-04-05
Applicant: ABBOTT LABORATORIES
Inventor： ABBOTT LABORATORIES , GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
IPC: C12Q01/70
CPC classification number: G01N33/56988
Abstract: An assay to simultaneously detect the presence of HIV antigen analyte and/or HIV-1 antibody and/or HIV-2 antibody in a test sample. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by analyte-specific indicator reagents.
Abstract translation: 在测试样品中同时检测HIV抗体分析物和/或HIV-1抗体和/或HIV-2抗体的存在的测定法。 分析物被捕获在相同或不同的固相上，并且通过检测由分析物特异性指示剂试剂产生的信号来确定分析物的存在。
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公开(公告)号：EP0644950A1
公开(公告)日：1995-03-29
申请号：EP93908748.0
申请日：1993-04-05
Applicant: ABBOTT LABORATORIES
Inventor： GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
IPC: G01N33
CPC classification number: G01N33/56988
Abstract: An assay to simultaneously detect the presence of HIV antigen analyte and/or HIV-1 antibody and/or HIV-2 antibody in a test sample. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by analyte-specific indicator reagents.
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5.发明公开DETECTION OF DIFFERENT HIV GENOTYPES UTILIZING A SYNTHETIC PEPTIDE-MODIFIED IMMUNOASSAY 失效NACHWEISS不同的HIV基因型用合成肽修饰的免疫测试
公开(公告)号：EP0763204A1
公开(公告)日：1997-03-19
申请号：EP95915635.0
申请日：1995-04-10
Applicant: Abbott Laboratories
Inventor： GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
CPC classification number: C07K14/005 , C07K2319/00 , C12N2740/16122 , G01N33/56988
Abstract: An assay to simultaneously detect the presence of one or more HIV subtypes of HIV-1 antibody and/or HIV-2 antibody in a test sample is disclosed. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by using a cocktail of synthetic and recombinant antigen-containing indicator reagents. Preferred indicator reagents include a synthetic19 amino acid cyclic peptide homologous to an immunodominant region of HIV-1 gp 41 and a synthetic19 amino acid cyclic peptide homologous to an immunodominant region of HIV-2 gp 36.
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6.发明公开HIV IMMUNOASSAY UTILIZING RECOMBINANT PROTEIN AND SYNTHETIC PEPTIDE REAGENTS 失效HIV免疫测定利用重组蛋白质和合成多肽试剂
公开(公告)号：EP0698214A1
公开(公告)日：1996-02-28
申请号：EP95911077.0
申请日：1995-02-21
Applicant: Abbott Laboratories
Inventor： GALLARDA, James, L. , STONE, Barbara, L. , LIU, Douglas, J. , HARRINGTON, Susan, K. , DAWSON, George, J. , WU, Ping
CPC classification number: G01N33/56988 , G01N33/68
Abstract: An assay to simultaneously detect the presence of HIV-1 antibody and/or HIV-2 antibody in a test sample is disclosed. The analytes are captured on either the same or different solid phases, and the presence of the analytes is determined by detecting a signal generated by using a cocktail of synthetic and recombinant antigen-containing indicator reagents.
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