公开(公告)号：WO1994006940A1

公开(公告)日：1994-03-31

申请号：PCT/US1993008759

申请日：1993-09-16

Applicant: ABBOTT LABORATORIES

Inventor： ABBOTT LABORATORIES ,  TASKAR, Suhas, P. ,  MALIEKAL, George ,  SPRONK, Adrian, M.

IPC: C12Q01/70

CPC classification number: G01N33/54366 ,  G01N33/5764

Abstract: The present invention provides an assay device (10) having a plurality of strips (2) affixed to one another by a handling means (4) which may (i) either contact the distal ends of the strips (2), wherein the strips (2) are separated by a distance suitable to allow the strips (2) to be simultaneously contacted to individual test samples; or, (ii) may involve a card upon which each of the strips (2) is individually mounted. The test samples travel from the proximal end (12) to the distal end of each strip (2) by capillary action, and the strips contain an immobilized capture reagent (6) which binds target analyte, an ancillary specific binding member or a labeled reagent, in proportion to the amount or presence of target analyte in the test sample. The handling means (4) simplifies the assay procedure and decreases the amount of time needed to perform a large number of assays. Preferably, a procedural control is provided on each strip (2).

Abstract translation: 本发明提供一种测定装置（10），其具有通过处理装置（4）彼此固定的多个条带（2），所述处理装置可以（i）接触条带（2）的远端，其中条带 2）分开一段距离，适合于允许条带（2）同时接触各个测试样品; 或者，（ii）可以涉及一个卡片，每个条带（2）单独安装在该卡片上。 测试样品通过毛细管作用从近端（12）移动到每条（2）的远端，并且条含有固定的捕获试剂（6），其结合靶分析物，辅助特异性结合成员或标记试剂 ，与测试样品中的目标分析物的量或存在成比例。 处理装置（4）简化了测定程序并减少了进行大量测定所需的时间。 优选地，在每个条带（2）上提供程序控制。