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公开(公告)号:EP1337555A2
公开(公告)日:2003-08-27
申请号:EP01987213.4
申请日:2001-11-15
Applicant: ABBOTT LABORATORIES
Inventor: FESIK, Stephen, W. , PETROS, Andrew, M. , YOON, HoSup , NETTESHEIM, David, G.
IPC: C07K14/47
CPC classification number: C07K14/4747
Abstract: Mutant peptides derived from wild-type human Bcl-2 are disclosed. Assays to identify substances which block the ability of Bcl-2 to inhibit apoptosis also are disclosed.