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公开(公告)号：MY162760A
公开(公告)日：2017-07-14
申请号：MYPI2010001141
申请日：2008-09-17
Applicant: ABBVIE BAHAMAS LTD
Inventor： WAGNER ROLF , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , TUFANO MICHAEL D , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , STEWART KENT D , ZHANG GEOFF G Z , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10
Abstract: THIS INVENTION RELATES TO:(A) COMPOUNDS AND SALTS THEREOF THAT,INTER ALIA, INHIBIT HCV;(B) INTERMEDIATES USEFUL FOR THE PREPARATION OF SUCH COMPOUNDS AND SALTS;(C) COMPOSITIONS COMPRISING SUCH COMPOUNDS AND SALTS;(D) METHODS FOR PREPARING SUCH INTERMEDIATES,COMPOUNDS,SALTS,AND COMPOSITIONS;(E) METHODS OF USE OF SUCH COMPOUNDS,SALTS, AND COMPOSITIONS;AND (F) KITS COMPRISING SUCH COMPOUNDS,SALTS, AND COMPOSITIONS.
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公开(公告)号：CY1115893T1
公开(公告)日：2017-01-25
申请号：CY141100943
申请日：2014-11-12
Applicant: ABBVIE BAHAMAS LTD
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: Ηεφεύρεσηαυτήαφορά: (α) ενώσειςκαιάλατααυτώνταοποία, μεταξύάλλων, αναστέλλουν HCV, (β) ενδιάμεσαχρήσιμαγιατηνπαρασκευήτέτοιωνενώσεωνκαιαλάτων, (γ) συνθέσειςπουπεριλαμβάνουντέτοιεςενώσειςκαιάλατα, (δ) μεθόδουςγιαπαρασκευήτέτοιωνενδιαμέσων, ενώσεων, αλάτωνκαισυνθέσεων, (ε) μεθόδουςγιαχρήσητέτοιων, ενώσεων, αλάτωνκαισυνθέσεωνκαι (ζ) κιτπουπεριλαμβάνουντέτοιεςενώσεις, άλατακαισυνθέσεις.
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公开(公告)号：CY1115514T1
公开(公告)日：2016-04-13
申请号：CY111101065
申请日：2011-11-03
Applicant: ABBVIE BAHAMAS LTD
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK THADDEUS S II , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: Ηεφεύρεσηαυτήαφορά: (α) ενώσειςκαιάλατααυτώνταοποία, μεταξύάλλων, αναστέλλουν HCV, (β) ενδιάμεσαχρήσιμαγιατηνπαρασκευήτέτοιωνενώσεωνκαιαλάτων, (γ) συνθέσειςπουπεριλαμβάνουντέτοιεςενώσειςκαιάλατα, (δ) μεθόδουςγιαπαρασκευήτέτοιωνενδιαμέσων, ενώσεων, αλάτωνκαισυνθέσεων, (ε) μεθόδουςγιαχρήσητέτοιων, ενώσεων, αλάτωνκαισυνθέσεωνκαι (ζ) κιτπουπεριλαμβάνουντέτοιεςενώσεις, άλατακαισυνθέσεις.
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公开(公告)号：DK2368882T3
公开(公告)日：2014-12-01
申请号：DK11171399
申请日：2008-09-17
Applicant: ABBVIE BAHAMAS LTD
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z , BARNES DAVID M
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10
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公开(公告)号：PE02092013A1
公开(公告)日：2013-03-24
申请号：PE0020732012
申请日：2008-09-17
Applicant: ABBVIE BAHAMAS LTD
Inventor： WAGNER ROLF , TUFANO MICHAEL D , STERWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , FRANCZYK THADDEUS II , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , C07D239/54 , C07D401/10 , C07D409/10 , C07D417/10
CPC classification number: A61K31/513 , A61K31/5377 , C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D405/10 , C07D409/10 , C07D413/10 , C07D417/10 , C07D417/14
Abstract: SE REFIERE A UN COMPUESTO DE FORMULA (I) DONDE: ---- ES UN ENLACE SIMPLE CARBONO-CARBONO Y UN ENLACE DOBLE CARBONO-CARBONO; R1 ES H, METILO, Y GRUPO PROTECTOR DE N; R2 ES H, HALO, HIDROXI, METILO, CICLOPROPILO Y CICLOBUTILO; R3 ES H, HALO, OXO, Y METILO; R4 ES HALO, NITRO, CIANO, AZIDO, ENTRE OTROS; R5 ES H, HIDROXI, ALQUILO, ALQUENILO, ENTRE OTROS; L ES UN ENLACE, OC(H)2, C(H)2O, ALQUILENO C1-C2, CICLOPROPIL-1,2-ENO; R6 ES CARBOCICLILO DE 2 ANILLOS FUSIONADOS Y HETEROCICLILO DE 2 ANILLOS FUSIONADOS. ES UN COMPUESTO PREFERIDO N-(6-(5-(2,4-DIOXO-3,4-DIHIDROPIRIMIDIN-1(2H)-IL)-3-IODO-2-METOXIFENIL)NAFTALEN-2-IL)METANSULFONAMIDA, ENTRE OTROS. DICHO COMPUESTO TIENE UN PATRON DE DIFRACCION DE RAYOS X DE POLVOS EXPRESADOS EN GRADOS 2 TETHA DE: 8,3 ± 0,2, 9,7 ± 0,2, 10,6 ± 0,2, 13,6 ± 0,2, 17,2 ± 0,2, 19,2 ± 0,2, 22, 22,7 ± 0,2, ENTRE OTROS. REFERIDO ADEMAS A UNA COMPOSICION FARMACEUTICA Y A UN PROCEDIMIENTO DE PREPARACION. DICHO COMPUESTO ES INHIBIDOR DEL VIRUS DE LA HEPATITIS C
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Patent Agency Ranking
公开(公告)号：DOP2010000396A
公开(公告)日：2013-12-31
申请号：DO2010000396
申请日：2010-12-21
Applicant: ABBVIE BAHAMAS LTD
Inventor： STEWART KENT D , ZHANG GEOFF G Z , CHEN SHUANG , HENRY RODGER F , WAGNER ROLF , TUFANO MICHAEL D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , FRANCZYK THADDEUS S II
IPC: A61K31/513 , A61P31/12 , C07D239/22 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: Esta invención se relaciona con: (a) compuestos y sales de los mismos que, entre otros, inhiben el HCV; (b) intermediarios de utilidad para Ia preparación de dichos compuestos y sales; (c) composiciones que comprenden dichos compuestos y sales; (d) métodos para preparar dichos intermediarios, compuestos, sales y composiciones; (e) métodos de uso de dichos compuestos, sales y composiciones; y (f) conjuntos de elementos que comprenden dichos compuestos, sales y composiciones.
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公开(公告)号：HK1156033A1
公开(公告)日：2012-06-01
申请号：HK11110421
申请日：2011-10-03
Applicant: ABBVIE BAHAMAS LTD
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D20060101 , A61K20060101 , A61P20060101
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公开(公告)号：HK1147256A1
公开(公告)日：2011-08-05
申请号：HK11101327
申请日：2011-02-11
Applicant: ABBVIE BAHAMAS LTD
Inventor： WAGNER ROLF , TUFANO MICHAEL D , STEWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G Z
IPC: C07D20060101 , A61K20060101 , A61P20060101
Abstract: This invention relates to: (a) compounds and salts thereof that, inter alia , inhibit HCV; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; and (e) use of such compounds, salts, and compositions.
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公开(公告)号：CR20150238A
公开(公告)日：2015-07-01
申请号：CR20150238
申请日：2015-05-08
Applicant: ABBVIE BAHAMAS LTD
Inventor： WAGNER ROLF , TUFANO MICHAEL D , STEWART KENT D , ROCKWAY TODD W , RANDOLPH JOHN T , PRATT JOHN K , MOTTER CHRISTOPHER E , MARING CLARENCE J , LONGENECKER KENTON L , LIU YAYA , LIU DACHUN , KRUEGER ALLAN C , KATI WARREN M , HUTCHINSON DOUGLAS K , HUANG PEGGY P , FLENTGE CHARLES A , DONNER PAMELA L , DEGOEY DAVID A , BETEBENNER DAVID A , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , HENRY RODGER F , KOTECKI BRIAN J , LOU XIAOCHUN , SARRIS KATHY , ZHANG GEOFF G Z
IPC: C07D239/22 , A61K31/513 , A61P31/12 , C07D239/54 , C07D401/10 , C07D403/10 , C07D409/10 , C07D413/10 , C07D417/10
Abstract: Esta invención se relaciona con: (a) compuestos y sales de los mismos que, entre otros, inhiben el HCV; (b) intermediarios de utilidad para la preparación de dichos compuestos y sales; (c) composiciones que comprenden dichos compuestos y sales; (d) métodos para preparar dichos intermediarios
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公开(公告)号：SI2368882T1
公开(公告)日：2015-02-27
申请号：SI200831329
申请日：2008-09-17
Applicant: ABBVIE BAHAMAS LTD
Inventor： FLENTGE CHARLES A , HUTCHINSON DOUGLAS K , BETEBENNER DAVID A , DEGOEY DAVID A , DONNER PAMELA L , KATI WARREN M , KRUEGER ALLAN C , LIU DACHUN , LIU YAYA , LONGENECKER KENTON L , MARING CLARENCE J , MOTTER CHRISTOPHER E , PRATT JOHN K , RANDOLPH JOHN T , ROCKWAY TODD W , STEWART KENT D , WAGNER ROLF , BARNES DAVID M , CHEN SHUANG , FRANCZYK II THADDEUS S , GAO YI , HAIGHT ANTHONY R , HENGEVELD JOHN E , KOTECKI BRIAN J , LOU XIAOCHUN , ZHANG GEOFF G Z
IPC: C07D239/00 , A61K31/00 , A61P31/00 , C07D401/00 , C07D403/00 , C07D405/00 , C07D409/00 , C07D413/00 , C07D417/00
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