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公开(公告)号：US20190167684A1
公开(公告)日：2019-06-06
申请号：US16272599
申请日：2019-02-11
Applicant: AbbVie Inc.
Inventor： Christine A. Collins , Daniel E. Cohen , Gennadiy Koev , Preethi Krishnan , Tami J. Pilot-Matias
IPC: A61K31/513 , A01N37/18 , A61K45/06 , A61K31/4025 , A61K38/05 , A61K38/00
Abstract: This disclosure is directed to pharmaceutical compositions that comprise two or more therapeutic agents that, inter alia, are useful for inhibiting hepatitis C virus (HCV) and methods for inhibiting HCV by co-administering two or more anti-HCV therapeutic agents.
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公开(公告)号：US20160068521A1
公开(公告)日：2016-03-10
申请号：US14786454
申请日：2014-04-22
Applicant: ABBVIE INC.
Inventor： Iok Chan Ng , M-akhteruzzaman Molla , Tami J. Pilot-Matias , Anil Vasudevan , Tatyana Dekhtyar , Artour Gomtsian , Katerina Sarris , Ana Aguirre , Mikhail Chafeev
IPC: C07D417/14 , A61K31/506 , A61K31/501 , A61K31/4178 , A61K31/433 , A61K31/4439 , A61K31/427 , C07D403/14
CPC classification number: C07D417/14 , A61K31/4178 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/501 , A61K31/506 , A61K45/06 , C07D403/14
Abstract: This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit RSV infection and/or replication; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
Abstract translation: 本公开涉及：（a）其特别是抑制RSV感染和/或复制的化合物及其盐; （b）可用于制备这些化合物和盐的中间体; （c）包含这些化合物和盐的组合物; （d）制备这种中间体，化合物，盐和组合物的方法; （e）使用这些化合物，盐和组合物的方法; 和（f）包含这些化合物，盐和组合物的试剂盒。
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公开(公告)号：US10233179B2
公开(公告)日：2019-03-19
申请号：US14786454
申请日：2014-04-22
Applicant: AbbVie Inc.
Inventor： Iok Chan Ng , M-akhteruzzaman Molla , Tami J. Pilot-Matias , Anil Vasudevan , Tatyana Dekhtyar , Artour Gomtsian , Kathy Sarris , Ana Aguirre , Mikhail Chafeev
IPC: C07D417/14 , C07D403/14 , A61K45/06 , A61K31/4178 , A61K31/427 , A61K31/433 , A61K31/4439 , A61K31/501 , A61K31/506
Abstract: This disclosure relates to: (a) compounds and salts thereof that, inter alia, inhibit RSV infection and/or replication; (b) intermediates useful for the preparation of such compounds and salts; (c) compositions comprising such compounds and salts; (d) methods for preparing such intermediates, compounds, salts, and compositions; (e) methods of use of such compounds, salts, and compositions; and (f) kits comprising such compounds, salts, and compositions.
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Patent Agency Ranking
公开(公告)号：US10201584B1
公开(公告)日：2019-02-12
申请号：US14247975
申请日：2014-04-08
Applicant: AbbVie Inc.
Inventor： Christine A. Collins , Daniel E. Cohen , Gennadiy Koev , Preethi Krishnan , Tami J. Pilot-Matias
IPC: A01N37/18 , A61K38/00 , A61K31/33 , A61K31/00 , A61K31/505 , A61K31/435 , A61K31/44 , A61K31/41 , A61K31/40 , A61K31/27 , A61K31/16 , A01N43/00 , A01N43/58 , A01N43/54 , A01N43/40 , A01N43/42 , A01N43/64 , A01N43/36 , A01N43/38 , A01N47/10 , A01N41/02 , C07D471/04 , C07D471/22 , C07D487/04 , A61P1/16 , A61K38/05 , A61K31/513 , A61K45/06
Abstract: This disclosure is directed to pharmaceutical compositions that comprise two or more therapeutic agents that, inter alia, are useful for inhibiting hepatitis C virus (HCV) and methods for inhibiting HCV by co-administering two or more anti-HCV therapeutic agents.
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公开(公告)号：US20140080886A1
公开(公告)日：2014-03-20
申请号：US14029333
申请日：2013-09-17
Applicant: AbbVie Inc.
Inventor： Tami J. Pilot-Matias , Preethi Krishnan , Warren M. Kati , Christine A. Collins , Neeta C. Mistry , Clarence J. Maring , David A. DeGoey , John K. Pratt , Dachun Liu , Rolf Wagner
IPC: A61K31/4025 , A61K45/06
CPC classification number: A61K31/4025 , A61K31/401 , A61K45/06 , A61K2300/00
Abstract: Pan-genotypic HCV inhibitors are described. This invention also relates to methods of using these inhibitors to treat HCV infection.
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公开(公告)号：US10201541B1
公开(公告)日：2019-02-12
申请号：US15398390
申请日：2017-01-04
Applicant: AbbVie Inc.
Inventor： Christine A. Collins , Daniel E. Cohen , Gennadiy Koev , Preethi Krishnan , Tami J. Pilot-Matias
IPC: A01N37/18 , A61K38/00 , A61K31/33 , A61K31/00 , A61K31/505 , A61K31/435 , A61K31/44 , A61K31/41 , A61K31/40 , A61K31/27 , A61K31/16 , A01N43/00 , A01N43/58 , A01N43/54 , A01N43/40 , A01N43/42 , A01N43/64 , A01N47/10 , A01N41/02 , C07D471/04 , C07D471/22 , C07D487/04 , A61P1/16 , A61K31/513 , A61K31/4025 , A61K45/06 , A61K38/05
Abstract: This disclosure is directed to pharmaceutical compositions that comprise two or more therapeutic agents that, inter alia, are useful for inhibiting hepatitis C virus (HCV) and methods for inhibiting HCV by co-administering two or more anti-HCV therapeutic agents.
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公开(公告)号：US09249138B2
公开(公告)日：2016-02-02
申请号：US14017901
申请日：2013-09-04
Applicant: ABBVIE INC.
Inventor： David A. Degoey , Pamela L. Donner , Warren M. Kati , Charles W. Hutchins , Allan C. Krueger , John T. Randolph , Christopher E. Motter , Preethi Krishnan , Neeta C. Mistry , Tami J. Pilot-Matias , Sachin V. Patel , Xiaoyan Li , Todd N. Soltwedel , Lissa T. Nelson
IPC: C07D239/48 , C07D471/04
CPC classification number: C07D471/04 , C07D239/48
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) are described. This invention also relates to processes of making such compounds, compositions comprising such compounds, and methods of using such compounds to treat HCV infection.
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公开(公告)号：US20150119400A1
公开(公告)日：2015-04-30
申请号：US14523692
申请日：2014-10-24
Applicant: AbbVie, Inc.
Inventor： Iok C. Ng , Liangjun Lu , Tanya Dekhtyar , Thomas Reisch , Rakesh L. Tripathi , Ron Pithawalla , Christine A. Collins , Tami J. Pilot-Matias
IPC: A61K31/498 , A61K45/06
CPC classification number: A61K31/498 , A61K31/7056 , A61K45/06 , A61K2300/00
Abstract: Pan-genotypic HCV inhibitors are described. This invention also relates to methods of using these inhibitors to treat HCV infection.
Abstract translation: 描述了泛基因型HCV抑制剂。 本发明还涉及使用这些抑制剂治疗HCV感染的方法。
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