公开(公告)号：AU6250000A

公开(公告)日：2001-04-12

申请号：AU6250000

申请日：2000-10-05

Applicant: ACADEMIA SINICA

Inventor： HWANG JAULANG ,  TING CHUN-JEN ,  HSU CHIA-TSE

IPC: A61K39/00 ,  C07K7/23 ,  C07K14/07 ,  C07K14/21 ,  C12N15/16 ,  C12N15/31 ,  C12N15/39 ,  C07K14/575 ,  C07H21/02 ,  C07H21/04 ,  C07K16/26 ,  C07K19/00 ,  A61K38/22 ,  A61P37/02

Abstract: A polypeptide comprising, (1) a receptor binding domain of a Pseudomonas exotoxin A or a functional variant thereof, and (2) at least two copies of a peptide sequence.

公开(公告)号：AU772387B2

公开(公告)日：2004-04-29

申请号：AU6250000

申请日：2000-10-05

Applicant: ACADEMIA SINICA

Inventor： HWANG JAULANG ,  HSU CHIA-TSE ,  TING CHUN-JEN

IPC: A61K39/00 ,  C07K7/23 ,  C07K14/07 ,  C07K14/21 ,  C12N15/16 ,  C12N15/31 ,  C12N15/39 ,  C07K14/575 ,  A61K38/22 ,  A61P37/02 ,  C07H21/02 ,  C07H21/04 ,  C07K16/26 ,  C07K19/00

Abstract: A polypeptide comprising, (1) a receptor binding domain of a Pseudomonas exotoxin A or a functional variant thereof, and (2) at least two copies of a peptide sequence.

公开(公告)号：DE60037626D1

公开(公告)日：2008-02-14

申请号：DE60037626

申请日：2000-05-19

Applicant: ACADEMIA SINICA

Inventor： HWANG JAULANG ,  HSU CHIA-TSE ,  TING CHUN-JEN

IPC: C12N15/31 ,  A61K38/09 ,  A61K39/00 ,  A61K39/104 ,  A61K39/285 ,  A61K39/295 ,  A61K48/00 ,  C07K7/23 ,  C07K14/07 ,  C07K14/21 ,  C12N15/16 ,  C12N15/39 ,  C12N15/62

Abstract: A polypeptide comprising, (1) a receptor binding domain of a Pseudomonas exotoxin A or a functional variant thereof, and (2) at least two copies of a peptide sequence.

公开(公告)号：CA2304377A1

公开(公告)日：2001-04-05

申请号：CA2304377

申请日：2000-04-28

Applicant: ACADEMIA SINICA

Inventor： HWANG JAULANG ,  HSU CHIA-TSE ,  TING CHUN-JEN

IPC: A61K39/00 ,  C07K7/23 ,  C07K14/07 ,  C07K14/21 ,  C12N15/16 ,  C12N15/31 ,  C12N15/39 ,  C12N15/11 ,  C07K19/00 ,  C12P21/00 ,  C12N15/12 ,  C07K14/47 ,  C12N15/62

Abstract: The invention relates to a polypeptide including (1) a receptor binding domain of a Pseudomonas exotoxin A, and (2) at least two copies of a peptide sequence.

公开(公告)号：NZ507368A

公开(公告)日：2001-06-29

申请号：NZ50736800

申请日：2000-10-05

Applicant: ACADEMIA SINICA INC

Inventor： HSU CHIA-TSE ,  TING CHUN-JEN ,  HWANG JAULANG

IPC: A61K39/00 ,  C07K7/23 ,  C07K14/07 ,  C07K14/21 ,  C12N15/16 ,  C12N15/31 ,  C12N15/39 ,  C07K19/00 ,  C07K14/59 ,  A61K39/104

Abstract: The polypeptide includes a receptor binding domain of a Pseudomonas exotoxin A, and at least two copies of a peptide sequence selected from a gonadotropin releasing hormone and a fragment of a vaccinia virus coat protein. The polypeptide may be used in vaccines.