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1.发明申请ANTIBODIES SPECIFIC TO A NOVEL EPITOPE ON CEMX OF HUMAN MEMBRANE-BOUND IGE AND USES THEREOF IN TREATING IGE-MEDIATED DISEASES 审中-公开人体膜结合IGE CEMX上新型表位特异性抗体及其在治疗IGE介导的疾病中的应用
公开(公告)号：WO2014165028A8
公开(公告)日：2014-12-04
申请号：PCT/US2014024172
申请日：2014-03-12
Applicant: ACADEMIA SINICA , LIANG CHI MING
Inventor： CHANG TSE WEN , LIN CHIEN-JEN , LU CHIEN-SHENG
IPC: C07K16/18 , A61K39/395 , C12N15/13
CPC classification number: C07K16/4291 , C07K7/04 , C07K2317/34 , C07K2317/52 , C07K2317/73
Abstract: The present disclosure relates to anti-IgE antibodies that bind to novel antigenic epitopes of the CsmX domain, e.g., SVPHPRCHCGAGRA (SEQ ID NO:4) and the uses thereof in treating IgE-mediated diseases.
Abstract translation: 本公开涉及结合CsmX结构域的新型抗原表位（例如SVPHPRCHCGAGRA（SEQ ID NO：4））的抗IgE抗体及其在治疗IgE介导的疾病中的用途。
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2.发明公开ANTIBODIES SPECIFIC TO A NOVEL EPITOPE ON CEMX OF HUMAN MEMBRANE-BOUND IGE AND USES THEREOF IN TREATING IGE-MEDIATED DISEASES 审中-公开特异性抗体一种新的表位，其CEMX人膜IGE和用于治疗的IgE介导的疾病
公开(公告)号：EP2970454A4
公开(公告)日：2016-08-31
申请号：EP14779722
申请日：2014-03-12
Applicant: ACADEMIA SINICA TAIWAN
Inventor： CHANG TSE WEN , LIN CHIEN-JEN , LU CHIEN-SHENG
IPC: C07K16/18 , A61K39/395 , C07K16/42 , C12N15/13
CPC classification number: C07K16/4291 , C07K7/04 , C07K2317/34 , C07K2317/52 , C07K2317/73
Abstract: The present disclosure relates to anti-IgE antibodies that bind to novel antigenic epitopes of the CsmX domain, e.g., SVPHPRCHCGAGRA (SEQ ID NO: 4) and the uses thereof in treating IgE-mediated diseases.
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