公开(公告)号：CA2609742A1

公开(公告)日：2006-11-30

申请号：CA2609742

申请日：2006-05-25

Applicant: ADA FOUNDATION

Inventor： CHOW LAWRENCE C ,  XU HUAKUN ,  SUN LIMIN ,  TAKAGI SHOZO

IPC: A61K6/884 ,  A61L27/14 ,  C08K3/04 ,  C08K3/32 ,  C08K3/34 ,  C08K3/40

Abstract: Combining nanosized particles of a source of desired dental restorative, repair or therapeutic materials with strengthening agents in various generally nanosized form such as whiskers, fibers, particles and the like in a resin matrix provides a highly strain resistant composite which more effectively releases the therapeutic agents. The utilization of nano sized particles of the therapeutic agent in the combination enables observation of significantly improved therapeutic results.

公开(公告)号：CA2593543A1

公开(公告)日：2006-07-20

申请号：CA2593543

申请日：2006-01-12

Applicant: ADA FOUNDATION

Inventor： XU HUAKUN ,  WEIR MICHAEL D

IPC: A61K35/32

Abstract: Living cellular material is encapsulated or placed in a protective material (cell protector) which is biocompatible, biodegradable and has a three-dimensional form. The three dimensional form is incorporated into a matrix that maybe implanted in vivo, ultimately degrade and thereby by replaced by living cell generated material.

公开(公告)号：WO2006127989B1

公开(公告)日：2007-02-15

申请号：PCT/US2006020409

申请日：2006-05-25

Applicant: ADA FOUNDATION ,  XU HUAKUN ,  SUN LIMIN ,  TAKAGI SHOZO ,  CHOW LAWRENCE C

Inventor： XU HUAKUN ,  SUN LIMIN ,  TAKAGI SHOZO ,  CHOW LAWRENCE C

IPC: A61K6/08 ,  A61L27/14 ,  C08K3/04 ,  C08K3/32 ,  C08K3/34 ,  C08K3/40

CPC classification number: A61L27/54 ,  A61L27/44 ,  A61L2300/112 ,  A61L2300/624 ,  A61L2400/12

Abstract: Combining nanosized particles of a source of desired dental restorative, repair or therapeutic materials with strengthening agents in various generally nanosized form such as whiskers, fibers, particles and the like in a resin matrix provides a highly strain resistant composite which more effectively releases the therapeutic agents. The utilization of nano sized particles of the therapeutic agent in the combination enables observation of significantly improved therapeutic results.

Abstract translation: 将所需牙科修复剂，修复或治疗材料源的纳米尺寸颗粒与各种通常纳米尺寸形式的增强剂（例如晶须，纤维，颗粒等）在树脂基质中组合提供了高度耐应变的复合材料，其更有效地释放治疗剂 。 联合使用治疗剂的纳米尺寸颗粒可以观察到明显改善的治疗结果。

公开(公告)号：WO2006076416A3

公开(公告)日：2009-04-16

申请号：PCT/US2006000955

申请日：2006-01-12

Applicant: ADA FOUNDATION ,  XU HUAKUN ,  WEIR MICHAEL D

Inventor： XU HUAKUN ,  WEIR MICHAEL D

IPC: C12N5/00 ,  A61K9/00

CPC classification number: A61K38/1841 ,  A61K38/1825 ,  A61K38/1858 ,  A61K38/1875 ,  A61L27/20 ,  A61L27/38 ,  A61L27/425 ,  A61L27/46 ,  A61L27/58 ,  A61L2400/06 ,  A61L2430/02 ,  C08L67/04 ,  C08L89/06 ,  C08L5/04 ,  C08L5/08

Abstract: Living cellular material is encapsulated or placed in a protective material (cell protector) which is biocompatible, biodegradable and has a three-dimensional form. The three dimensional form is incorporated into a matrix that maybe implanted in vivo, ultimately degrade and thereby by replaced by living cell generated material.

Abstract translation: 活细胞材料被包封或放置在生物相容性，可生物降解和具有三维形式的保护材料（细胞保护剂）中。 三维形式被结合到可以植入体内的基质中，最终降解，从而被活细胞产生的材料代替。