公开(公告)号：AU2494199A

公开(公告)日：1999-08-23

申请号：AU2494199

申请日：1999-02-03

Applicant: ANGIOSONICS INC

Inventor： ROSENSCHEIN URI ,  ROZESZJAN ARIE

IPC: A61B18/00 ,  A61B17/22 ,  A61K31/16 ,  A61K31/407 ,  A61K41/00 ,  A61K45/00 ,  A61M37/00 ,  A61P9/00 ,  A61P43/00

公开(公告)号：CA2320300A1

公开(公告)日：1999-08-12

申请号：CA2320300

申请日：1999-02-03

Applicant: ANGIOSONICS INC

Inventor： ROZESZJAN ARIE ,  ROSENSCHEIN URI

IPC: A61B18/00 ,  A61B17/22 ,  A61K31/16 ,  A61K31/407 ,  A61K41/00 ,  A61K45/00 ,  A61M37/00 ,  A61P9/00 ,  A61P43/00

Abstract: A system and method for inhibiting restenosis by compromising the migration, viability and adhesion of mammalian smooth muscle cells (SMC). The system includes an ultrasonic energy source; a transmitter for transmitting the ultrasonic energy to the SMC and a drug delivery spectrum for delivering drugs to the smooth mucles cells. This system and method is especially useful in the prevention of restenosis in a blood vessel of a mammal associated with the migration of SMC in the blood vessel following vascular intervention, such as angioplasty.