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    6.
    发明专利
    未知

    公开(公告)号：AT155908T

    公开(公告)日：1997-08-15

    申请号：AT90905998

    申请日：1990-03-13

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： CHAMOUN NASSIB G

    IPC: A61B5/11 ,  A61B5/16 ,  A61B5/374 ,  G01R23/16 ,  G06F17/00 ,  G06K9/00 ,  G06F159/00 ,  A61B5/048

    Abstract: Disclosed is a real time cerebral diagnostic apparatus and method for quantitatively evaluating, in a noninvasive manner, cerebral phenomena such as the depth and adequacy of anesthesia pain responses during surgical stress, acute cerebral ischemia, level of consciousness, degree of intoxication and ongoing normal and abnormal cognitive processes. A suitable electrode and amplifier system is used to obtain high resolution biopotentials from the regions of interest. Surface electroencephalographic (EEG) signals are filtered to allow the acquisition of frequencies between 2 and 500 Hz, then digitized and transmitted over a high speed serial line to a host computer where a 32 second long signal is divided into 128 consecutive 0.25 second intervals. Digital EEG data from unipolar leads is normalized and the dynamic phase and density relations within the signal are then characterized by estimating the third-order autocorrelation function or autobispectrum using either a frequency domain, or parametric approach. Paired EEG data from corresponding left and right hemisphere leads is used to characterize the dynamic phase and density relations between hemispheres by estimating the third order crosscorrelation function or crossbispectrum using either frequency domain or parametric techniques. Under certain specific filtering circumstances the power spectrum and crosspower spectrum are also computed. A reference clinical database is used to identify frequency pairs most sensitive to particular interventions or diagnostic states of interest. The values at these frequency pairs are then extracted from the patient's autobicoherence, autobispectral density, autobiphase, crossbicoherence, crossbispectral density, and crossbiphase arrays. The ensemble of values for the particular diagnostic determination is used to compute an index which serves as the diagnostic criterion by which the patient's state is judged. Any diagnostic index can be continuously displayed on a graphics terminal for real-time diagnostic monitoring or can be sent to a hard copy device to generate reports for the medical record.

    CEREBRAL BIOPOTENTIAL ANALYSIS SYSTEM AND METHOD
    8.
    发明专利
    CEREBRAL BIOPOTENTIAL ANALYSIS SYSTEM AND METHOD 未知

    公开(公告)号：AU5410090A

    公开(公告)日：1990-11-05

    申请号：AU5410090

    申请日：1990-03-13

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： CHAMOUN NASSIB G

    IPC: A61B5/11 ,  A61B5/16 ,  A61B5/374 ,  G01R23/16 ,  G06F17/00 ,  G06K9/00 ,  A61B5/04

    Abstract: Disclosed is a real time cerebral diagnostic apparatus and method for quantitatively evaluating, in a noninvasive manner, cerebral phenomena such as the depth and adequacy of anesthesia pain responses during surgical stress, acute cerebral ischemia, level of consciousness, degree of intoxication and ongoing normal and abnormal cognitive processes. A suitable electrode and amplifier system is used to obtain high resolution biopotentials from the regions of interest. Surface electroencephalographic (EEG) signals are filtered to allow the acquisition of frequencies between 2 and 500 Hz, then digitized and transmitted over a high speed serial line to a host computer where a 32 second long signal is divided into 128 consecutive 0.25 second intervals. Digital EEG data from unipolar leads is normalized and the dynamic phase and density relations within the signal are then characterized by estimating the third-order autocorrelation function or autobispectrum using either a frequency domain, or parametric approach. Paired EEG data from corresponding left and right hemisphere leads is used to characterize the dynamic phase and density relations between hemispheres by estimating the third order crosscorrelation function or crossbispectrum using either frequency domain or parametric techniques. Under certain specific filtering circumstances the power spectrum and crosspower spectrum are also computed. A reference clinical database is used to identify frequency pairs most sensitive to particular interventions or diagnostic states of interest. The values at these frequency pairs are then extracted from the patient's autobicoherence, autobispectral density, autobiphase, crossbicoherence, crossbispectral density, and crossbiphase arrays. The ensemble of values for the particular diagnostic determination is used to compute an index which serves as the diagnostic criterion by which the patient's state is judged. Any diagnostic index can be continuously displayed on a graphics terminal for real-time diagnostic monitoring or can be sent to a hard copy device to generate reports for the medical record.

    9.
    发明专利
    未知

    公开(公告)号：BRPI0719527A2

    公开(公告)日：2014-10-07

    申请号：BRPI0719527

    申请日：2007-10-12

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： BRUMER REBECCA ,  CHAMOUN NASSIB G ,  CORDERO RAFAEL M ,  DAVIDSON MARC ,  KIELY JAMES P

    IPC: A61B5/308 ,  H01Q1/22

    Abstract: This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor.

    10.
    发明专利
    未知

    公开(公告)号：BRPI0719524A2

    公开(公告)日：2014-06-03

    申请号：BRPI0719524

    申请日：2007-10-12

    Applicant: ASPECT MEDICAL SYSTEMS INC

    Inventor： BRUMER REBECCA ,  CHAMOUN NASSIB G ,  CORDERO RAFAEL M ,  DAVIDSON MARC ,  KIELY JAMES P

    IPC: G06K7/00 ,  A61B5/308 ,  G06K19/077

    Abstract: This invention relates to a physiological sensor which acquires pre-programmed data from an electrode or an electrode array using Radio Frequency Identification (RFID) technology. The source of the sensor may be authenticated by means of a wireless interface between an RFID transponder affixed to the electrode array, and an RFID interrogator embedded in the patient interface cable. The criteria for use are then verified to ensure that they are met by the electrode array before beginning signal acquisition. If the criteria are not met, a message is provided to the user via the monitor.

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