公开(公告)号：WO2011078980A1

公开(公告)日：2011-06-30

申请号：PCT/US2010/059885

申请日：2010-12-10

Applicant: ABBOTT LABORATORIES ,  KENDALL, Richard ,  ROCHE, John, W.

Inventor： KENDALL, Richard ,  ROCHE, John, W.

IPC: G01N33/72 ,  G01N1/28 ,  G01N15/14

CPC classification number: G01N15/1434 ,  G01N1/2813 ,  G01N15/1475 ,  G01N21/27 ,  G01N21/49 ,  G01N21/59 ,  G01N33/721 ,  G01N2001/282 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1486 ,  G01N2333/805

Abstract: A method for counting blood cells in a sample of whole blood. The method comprises the steps of: (a) providing a sample of whole blood; (b) depositing the sample of whole blood onto a slide, e.g., a microscope slide; (c) employing a spreader to create a blood smear; (d) allowing the blood smear to dry on the slide; (e) measuring absorption or reflectance of light attributable to the hemoglobin in the red blood cells in the blood smear on the slide; (f) recording a magnified two-dimensional digital image of the area of analysis identified by the measurement in step (e) as being of suitable thickness for analysis; and (g) collecting, analyzing, and storing data from the magnified two-dimensional digital image. Optionally, steps of fixing and staining of blood cells on the slide can be employed in the method.

Abstract translation: 一种全血样品中血细胞计数的方法。 该方法包括以下步骤：（a）提供全血样品; （b）将全血样品沉积在载玻片上，例如显微镜载片上; （c）使用吊具产生血液涂片; （d）允许血液涂片在载玻片上干燥; （e）测量归因于载玻片上血液涂片中红细胞中血红蛋白的光的吸光度或反射率; （f）将通过步骤（e）中的测量识别的分析区域的放大二维数字图像记录为具有适于分析的厚度; 和（g）从放大的二维数字图像中收集，分析和存储数据。 任选地，可以在该方法中使用在载玻片上固定和染色血细胞的步骤。

公开(公告)号：WO2009064748A1

公开(公告)日：2009-05-22

申请号：PCT/US2008/083167

申请日：2008-11-12

Applicant: ABBOTT LABORATORIES ,  KOKAWA, Hidesuke ,  KENDALL, Richard

Inventor： KOKAWA, Hidesuke ,  KENDALL, Richard

IPC: B01L9/06 ,  G01N35/00

CPC classification number: B01L9/06 ,  B01L2200/143 ,  B01L2300/02 ,  B01L2300/022 ,  G01N35/00732

Abstract: A device for enabling the user of a clinical analyzer, such as, for example, an automated clinical analyzer, e.g., an automated hematology analyzer, to identify samples that require additional processing subsequent to an initial run through the clinical analyzer. The device can also indicate the location of sample containers to assist the user in finding a sample from a sample retention area. The device comprises a rack comprising a plurality of receptacles, each receptacle having a recessed area for holding a sample container, e.g., a sample tube. Each receptacle is associated with an indicator for signaling when a sample container in a given receptacle area requires additional processing.

Abstract translation: 用于使临床分析仪的用户（例如，自动化临床分析仪，例如自动血液分析仪）能够识别在通过临床分析仪的初始运行之后需要额外处理的样品的装置。 设备还可以指示样品容器的位置，以帮助用户从样品保留区域中找到样品。 该装置包括一个包括多个容器的架子，每个容器具有用于保持样品容器例如样品管的凹陷区域。 每个容器与用于在给定容器区域中的样品容器需要额外处理时用于信号的指示器相关联。

公开(公告)号：EP2517023B1

公开(公告)日：2014-07-23

申请号：EP10793400.2

申请日：2010-12-10

Applicant: Abbott Laboratories

Inventor： KENDALL, Richard ,  ROCHE, John, W.

IPC: G01N33/72 ,  G01N1/28 ,  G01N15/14

CPC classification number: G01N15/1434 ,  G01N1/2813 ,  G01N15/1475 ,  G01N21/27 ,  G01N21/49 ,  G01N21/59 ,  G01N33/721 ,  G01N2001/282 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1486 ,  G01N2333/805

Abstract: A method for counting blood cells in a sample of whole blood. The method comprises the steps of: (a) providing a sample of whole blood; (b) depositing the sample of whole blood onto a slide, e.g., a microscope slide; (c) employing a spreader to create a blood smear; (d) allowing the blood smear to dry on the slide; (e) measuring absorption or reflectance of light attributable to the hemoglobin in the red blood cells in the blood smear on the slide; (f) recording a magnified two-dimensional digital image of the area of analysis identified by the measurement in step (e) as being of suitable thickness for analysis; and (g) collecting, analyzing, and storing data from the magnified two-dimensional digital image. Optionally, steps of fixing and staining of blood cells on the slide can be employed in the method.

公开(公告)号：EP2222405A1

公开(公告)日：2010-09-01

申请号：EP08850227.3

申请日：2008-11-12

Applicant: Abbott Laboratories

Inventor： KOKAWA, Hidesuke ,  KENDALL, Richard

IPC: B01L9/06 ,  G01N35/00

CPC classification number: B01L9/06 ,  B01L2200/143 ,  B01L2300/02 ,  B01L2300/022 ,  G01N35/00732

Abstract: A device for enabling the user of a clinical analyzer, such as, for example, an automated clinical analyzer, e.g., an automated hematology analyzer, to identify samples that require additional processing subsequent to an initial run through the clinical analyzer. The device can also indicate the location of sample containers to assist the user in finding a sample from a sample retention area. The device comprises a rack comprising a plurality of receptacles, each receptacle having a recessed area for holding a sample container, e.g., a sample tube. Each receptacle is associated with an indicator for signaling when a sample container in a given receptacle area requires additional processing.

公开(公告)号：EP2517023A1

公开(公告)日：2012-10-31

申请号：EP10793400.2

申请日：2010-12-10

Applicant: Abbott Laboratories

Inventor： KENDALL, Richard ,  ROCHE, John, W.

IPC: G01N33/72 ,  G01N1/28 ,  G01N15/14

CPC classification number: G01N15/1434 ,  G01N1/2813 ,  G01N15/1475 ,  G01N21/27 ,  G01N21/49 ,  G01N21/59 ,  G01N33/721 ,  G01N2001/282 ,  G01N2015/0073 ,  G01N2015/008 ,  G01N2015/1486 ,  G01N2333/805

Abstract: A method for counting blood cells in a sample of whole blood. The method comprises the steps of: (a) providing a sample of whole blood; (b) depositing the sample of whole blood onto a slide, e.g., a microscope slide; (c) employing a spreader to create a blood smear; (d) allowing the blood smear to dry on the slide; (e) measuring absorption or reflectance of light attributable to the hemoglobin in the red blood cells in the blood smear on the slide; (f) recording a magnified two-dimensional digital image of the area of analysis identified by the measurement in step (e) as being of suitable thickness for analysis; and (g) collecting, analyzing, and storing data from the magnified two-dimensional digital image. Optionally, steps of fixing and staining of blood cells on the slide can be employed in the method.