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1.Inhibitors of diacylglycerol o-acyltransferase type 1 enzyme 审中-公开
Title translation: 抑制二酰基甘油-O-酰基转移酶 - 酶呕类型1公开(公告)号:EP2452937A1
公开(公告)日:2012-05-16
申请号:EP12154263.3
申请日:2008-04-30
Applicant: Abbott Laboratories
Inventor: Judd, Andrew S , Mulhern, Mathew M , Iyengar, Rajesh R , Kym, Philip R , Souers, Andrew J
IPC: C07D277/20 , C07D401/04 , C07D401/12 , C07D401/14 , C07D417/04 , C07D417/12 , C07D417/14 , C07D493/08 , A61K31/427 , A61K31/44 , A61P3/04 , A61P3/10
CPC classification number: C07D417/04 , C07D213/40 , C07D213/75 , C07D277/28 , C07D277/82 , C07D405/04 , C07D417/12 , C07D417/14 , C07D498/08
Abstract: The present invention relates to compounds of formula (I): wherein Q, G 1 , G 2 , and G 3 , are defined herein. Pharmaceutical compositions and methods for treating DGAT-1 related diseases or conditions are also disclosed.
Abstract translation: 本发明涉及式(I)化合物:其中Q,G 1,G 2和G 3在本文中定义。 还公开了治疗DGAT-1相关疾病或病症的药物组合物和方法。