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公开(公告)号：WO2008133753A2
公开(公告)日：2008-11-06
申请号：PCT/US2007/088027
申请日：2007-12-19
Applicant: ABBOTT LABORATORIES , BETEBENNER, David A. , MARING, Clarence J. , ROCKWAY, Todd W. , COOPER, Curt S. , ANDERSON, David D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami J. , MASSE, Sherie Vl. , CARRICK, Robert J. , HE, Wenping , LU, Liangjun
Inventor： BETEBENNER, David A. , MARING, Clarence J. , ROCKWAY, Todd W. , COOPER, Curt S. , ANDERSON, David D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami J. , MASSE, Sherie Vl. , CARRICK, Robert J. , HE, Wenping , LU, Liangjun
IPC: A61K31/675
CPC classification number: C07D471/04 , C07D239/94 , C07D487/04 , C07D487/14 , C07D519/00
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
Abstract translation: 公开了有效抑制丙型肝炎病毒（HCV）或其他病毒复制的化合物。 本发明还涉及包含这些化合物的组合物，这些化合物与其它抗病毒剂或治疗剂的共配制或共同给药，用于合成这些化合物的方法和中间体，以及使用这些化合物治疗HCV或 其他病毒感染。
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2.发明公开NON-A, NON-B, NON-C, NON-D, NON-E HEPATITIS REAGENTS AND METHODS FOR THEIR USE 失效FOR NON-A，非B非C NON-D NON-E肝炎试剂和方法您使用
公开(公告)号：EP0745129A1
公开(公告)日：1996-12-04
申请号：EP95911823.0
申请日：1995-02-14
Applicant: Abbott Laboratories
Inventor： SIMONS, John N. , PILOT-MATIAS, Tami J. , DAWSON, George J. , SCHLAUDER, George G. , DESAI, Suresh M. , LEARY, Thomas P. , MUERHOFF, Anthony Scott , ERKER, James Carl , BUIJK, Sheri L. , MUSHAHWAR, Isa K.
Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
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公开(公告)号：EP2094276A2
公开(公告)日：2009-09-02
申请号：EP07874373.9
申请日：2007-12-19
Applicant: Abbott Laboratories
Inventor： BETEBENNER, David A. , MARING, Clarence J. , ROCKWAY, Todd W. , COOPER, Curt S. , ANDERSON, David D. , WAGNER, Rolf , ZHANG, Rong , MOLLA, Akhteruzzaman , MO, Hongmei , PILOT-MATIAS, Tami J. , MASSE, Sherie Vl. , CARRICK, Robert J. , HE, Wenping , LU, Liangjun
IPC: A61K31/675
CPC classification number: C07D471/04 , C07D239/94 , C07D487/04 , C07D487/14 , C07D519/00
Abstract: Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
Abstract translation: 公开了有效抑制丙型肝炎病毒（HCV）或其他病毒复制的化合物。 本发明还涉及包含此类化合物的组合物，这类化合物与其它抗病毒剂或治疗剂的共配制或共同施用，用于合成这些化合物的方法和中间体，以及使用此类化合物治疗HCV或 其他病毒感染。
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4.发明授权NON-A, NON-B, NON-C, NON-D, NON-E HEPATITIS REAGENTS AND METHODS FOR THEIR USE 失效FOR NON-A，非B非C NON-D NON-E肝炎试剂和方法您使用
公开(公告)号：EP0745129B1
公开(公告)日：2004-11-24
申请号：EP95911823.3
申请日：1995-02-14
Applicant: Abbott Laboratories
Inventor： SIMONS, John N. , PILOT-MATIAS, Tami J. , DAWSON, George J. , SCHLAUDER, George G. , DESAI, Suresh M. , LEARY, Thomas P. , MUERHOFF, Anthony Scott , ERKER, James Carl , BUIJK, Sheri L. , MUSHAHWAR, Isa K.
Abstract: Hepatitis GB Virus (HGBV) nucleic acid and amino acid sequences useful for a variety of diagnostic and therapeutic applications, kits for using the HGBV nucleic acid or amino acid sequences, HGBV immunogenic particles, and antibodies which specifically bind to HGBV. Also provided are methods for producing antibodies, polyclonal or monoclonal, from the HGBV nucleic acid or amino acid sequences.
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