公开(公告)号：DE4231297A1

公开(公告)日：1994-03-24

申请号：DE4231297

申请日：1992-09-18

Applicant: BASF AG

Inventor： KUEKENHOEHNER THOMAS DR ,  GOETZ NORBERT DR ,  FISCHER ROLF DR ,  SCHNURR WERNER DR ,  BORCHERS DIRK DR

IPC: C07D307/32 ,  C07D307/33

Abstract: 3-(2'-Oxyethyl)dihydro-2(3H)furanones of the general formula I in which R denotes hydrogen or acetyl, are prepared by reaction of ethylene oxide with acetoacetic acid esters of the general formula II in which R denotes C1- to C4-alkyl, by carrying out the reaction in alcoholic solutions in the presence of alkali metal alkoxides at temperatures from 20 to 100 DEG C and pressures from 1 to 20 bar.

公开(公告)号：HU0100289A2

公开(公告)日：2001-05-28

申请号：HU0100289

申请日：1998-12-02

Applicant: BASF AG

Inventor： BORCHERS DIRK DR ,  GOETZ NORBERT DR ,  HARTMANN HORST ,  KUEKENHOEHNER THOMAS DR ,  KOENIG HARTMANN DR ,  MAYWALD VOLKER DR ,  WAGNER RUPERT

IPC: C07D307/32 ,  C07D307/33 ,  C07D407/04

Abstract: A process for removing impurities from 3-(2'-acetoxyethyl)-dihydro-2(3H)-furanone (I), which comprises initially preparing the 3-(2'-acetoxyethyl)-dihydro-2(3H)-furanone containing the undesirable impurities in a manner known per se by acetylating 3-(2'-hydroxylethyl)-dihydro-2(3H)-furanone, subsequently treating it with strong mineral acids and finally removing the decomposition products of the undesirable impurities from I.

公开(公告)号：DE59304804D1

公开(公告)日：1997-01-30

申请号：DE59304804

申请日：1993-09-08

Applicant: BASF AG

Inventor： KUEKENHOEHNER THOMAS DR ,  GOETZ NORBERT DR ,  FISCHER ROLF DR ,  SCHNURR WERNER DR ,  BORCHERS DIRK DR

IPC: C07D307/32 ,  C07D307/33

Abstract: 3-(2'-Oxyethyl)dihydro-2(3H)furanones of the general formula I in which R denotes hydrogen or acetyl, are prepared by reaction of ethylene oxide with acetoacetic acid esters of the general formula II in which R denotes C1- to C4-alkyl, by carrying out the reaction in alcoholic solutions in the presence of alkali metal alkoxides at temperatures from 20 to 100 DEG C and pressures from 1 to 20 bar.

公开(公告)号：DE4228669A1

公开(公告)日：1994-03-03

申请号：DE4228669

申请日：1992-08-28

Applicant: BASF AG

Inventor： BORCHERS DIRK DR ,  FISCHER ROLF DR ,  GOETZ NORBERT DR ,  KUEKENHOEHNER THOMAS DR ,  SCHNURR WERNER DR

IPC: B01J21/04 ,  C07B61/00 ,  C07D309/08 ,  C07D307/32

Abstract: Tetrahydropyran-4-carboxylic acid and its esters of the general formula I in which R denotes hydrogen, C1- to C6-alkyl, C5- to C8-cycloalkyl or aryl, are prepared by reacting dihydro-2(3H)furanones of the general formula II in which R denotes hydrogen, C1- to C6-alkyl or -CO-R and R denotes hydrogen or C1- to C6-alkyl with water or alcohols of the general formula III R -OH (III> in which R has the abovementioned meaning, at temperatures from 200 to 350 DEG C in the presence of acidic heterogeneous catalysts, by employing fixed-bed acidic heterogeneous catalysts.

公开(公告)号：DE59308171D1

公开(公告)日：1998-04-02

申请号：DE59308171

申请日：1993-08-12

Applicant: BASF AG

Inventor： BORCHERS DIRK DR ,  FISCHER ROLF DR ,  GOETZ NORBERT DR ,  KUEKENHOEHNER THOMAS DR ,  SCHNURR WERNER DR

IPC: B01J21/04 ,  C07B61/00 ,  C07D309/08

Abstract: Tetrahydropyran-4-carboxylic acid and its esters of the general formula I in which R denotes hydrogen, C1- to C6-alkyl, C5- to C8-cycloalkyl or aryl, are prepared by reacting dihydro-2(3H)furanones of the general formula II in which R denotes hydrogen, C1- to C6-alkyl or -CO-R and R denotes hydrogen or C1- to C6-alkyl with water or alcohols of the general formula III R -OH (III> in which R has the abovementioned meaning, at temperatures from 200 to 350 DEG C in the presence of acidic heterogeneous catalysts, by employing fixed-bed acidic heterogeneous catalysts.

公开(公告)号：DE4415887A1

公开(公告)日：1995-06-01

申请号：DE4415887

申请日：1994-05-05

Applicant: BASF AG

Inventor： RANG HARALD DR ,  GOETZ NORBERT DR ,  HARREUS ALBRECHT DR ,  BORCHERS DIRK DR ,  MAYWALD VOLKER DR ,  HEIMANN FRANK DR ,  BUSCHULTE THOMAS DR ,  HARTMANN HORST

IPC: B01J23/02 ,  B01J31/02 ,  C07B61/00 ,  C07C239/20 ,  C07C249/12 ,  C07C251/54 ,  C07C309/66 ,  C07C309/04

Abstract: A process is disclosed for producing isomer mixtures from O-phenoxyalkylhydroxyl amines Ia: H2N-O-CH2-CH(R )-O-Ar and Ib: H2N-O-CH(R )-CH2-O-Ar (wherein R represents alkyl, Ar where appropriate a substituted phenyl) and the corresponding salt mixtures. This process involves the following steps: (a) an isomer mixture of O-(2-hydroxyethyl)-oximes (IIa) and (IIb) (in which R is an alkyl and R is an alkyl or alkoxy, or R and R together with the common C atom form a 5-7 member ring) is converted by reaction with a sulphonyl halogenide of formula (III): Hal-SO2-R (wherein R represents an organic group and Hal is a halogen) in the presence of a base to form the corresponding sulphonate mixture of (IVa) and (IVb); (b) this sulphonate mixture is reacted in the presence of a base with a phenol of formula (V): HO-Ar to produce a mixture of O-phenoxyalkyloximes of general formulae (VIa) and (VIb); (c) the mixture is hydrolysed in the presence of an acid and, if required, (d) the O-phenoxyalkylhydroxyl amines (Ia) and (Ib) are released from the resulting salts using a mineral base. The O-phenoxyalkylhydroxyl amines (Ia/Ib) and their precursors (VIa/VIb) are important intermediate products for plant protective agents and drugs.