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公开(公告)号：WO9910480A3
公开(公告)日：1999-05-27
申请号：PCT/EP9805275
申请日：1998-08-19
Applicant: BASF AG , BOEHM THOMAS , DEAR NEIL T
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K31/7105 , A61K38/00 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , C07K14/81 , C12N9/64 , C12Q1/37 , C12N15/57 , A61K31/00 , C07K16/40 , C12N5/10 , C12Q1/68 , G01N33/68
CPC classification number: C12N9/6472 , A61K38/00 , A61K48/00 , C07K14/8139 , G01N2333/96466
Abstract: The invention relates to new tissue-specific calpaines and their production. The invention also relates to a method for screening for new calpaine inhibitors and their use.
Abstract translation: 本发明涉及新的组织特异性钙蛋白酶及其制备。 此外，本发明涉及用于筛选新型钙蛋白酶抑制剂及其用途的方法。
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公开(公告)号：WO0202775A2
公开(公告)日：2002-01-10
申请号：PCT/EP0107457
申请日：2001-06-29
Applicant: BASF AG , BOEHM THOMAS , DEAR NEIL T
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K38/00 , A61K38/46 , A61K39/395 , A61K48/00 , A61P9/10 , A61P25/28 , A61P27/12 , A61P29/00 , A61P43/00 , C07K16/40 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12N9/64 , C12Q1/37 , C12Q1/68 , C12N15/52 , A61K38/43 , G01N33/577 , G01N33/68
CPC classification number: C12N9/6472 , A61K38/00 , A61K48/00
Abstract: The invention relates to calpain protease 12 (Capn12), which is characterized in that it has an amino acid sequence comprising amino acids 1 - 342 of SEQ ID NO: 1 or an amino acid sequence selected amongst SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3 or SEQ ID NO: 4. The invention also relates to the functional analogs of said calpain protease 12, to the nucleic acids coding therefor, to recombinant vectors containing said coding sequences and to microorganisms transfected therewith. The invention further relates to a method for recombinant production of Capn12 and to different applications of Capn12 and the nucleic acids coding therefor.
Abstract translation: 钙蛋白酶蛋白酶12（Capn12），其特征在于，一个氨基酸序列，其包含氨基酸SEQ ID NO 1-342：1或SEQ ID NO的氨基酸序列：1，SEQ ID NO：2，SEQ ID NO：3 或SEQ ID NO：4; 以及它们的功能类似物; 对于这种编码核酸; 含有这些编码序列的重组载体; 转染的微生物; 重组生产Capn12的方法; 以及Capn12和编码它的核酸的各种应用。
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公开(公告)号：WO0078933A2
公开(公告)日：2000-12-28
申请号：PCT/EP0005261
申请日：2000-06-07
Applicant: BASF AG , DEAR NEIL T , BOEHM THOMAS , MOELLER ACHIM
Inventor： DEAR NEIL T , BOEHM THOMAS , MOELLER ACHIM
IPC: G01N33/50 , A61K38/57 , A61K45/00 , A61P15/00 , A61P15/08 , C12N9/64 , C12N15/09 , C12Q1/37 , G01N33/15 , C12N9/00
CPC classification number: C12N9/6472 , A61K38/57
Abstract: The invention relates to a novel mammalian calpain CAPN11, to the synthesis and to the use thereof.
Abstract translation: 新的蛋白酶和它们的用途。
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公开(公告)号：AU737504B2
公开(公告)日：2001-08-23
申请号：AU5557698
申请日：1997-11-28
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K38/00 , A61K38/55 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/00 , C07K14/81 , C12N9/64 , C12N15/12 , C12N15/57 , C12Q1/37 , C12Q1/68 , C12N5/10 , C07K16/40 , A61K31/70
Abstract: Novel calpains and their preparation, and methods for screening for novel calpain inhibitors and their use are described.
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公开(公告)号：BR9811365A
公开(公告)日：2000-08-22
申请号：BR9811365
申请日：1998-08-19
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K31/7105 , A61K38/00 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , C07K14/81 , C12N9/64 , C12Q1/37 , C12N9/00
Abstract: The invention relates to new tissue-specific calpaines and their production. The invention also relates to a method for screening for new calpaine inhibitors and their use.
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Patent Agency Ranking
公开(公告)号：CZ2000680A3
公开(公告)日：2000-06-14
申请号：CZ2000680
申请日：1998-08-19
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N9/00
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公开(公告)号：ZA987660B
公开(公告)日：2000-02-25
申请号：ZA987660
申请日：1998-08-25
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K31/7105 , A61K38/00 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , C07K14/81 , C12N9/64 , C12Q1/37 , C12N , C12Q , C07K
Abstract: The invention relates to new tissue-specific calpaines and their production. The invention also relates to a method for screening for new calpaine inhibitors and their use.
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公开(公告)号：CA2274304A1
公开(公告)日：1998-06-11
申请号：CA2274304
申请日：1997-11-28
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K38/00 , A61K38/55 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P29/00 , A61P35/00 , A61P37/00 , C07K14/81 , C12N9/64 , C12N15/12 , C12N15/57 , C12Q1/37 , C12Q1/68 , C12N5/10 , C07K16/40 , A61K31/70
Abstract: The invention relates to novel calpaines and their production. The invention further relates to a screening method for new calpaine inhibitors and the use thereof.
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公开(公告)号：BR0011721A
公开(公告)日：2002-03-05
申请号：BR0011721
申请日：2000-06-07
Applicant: BASF AG
Inventor： DEAR NEIL T , BOHM THOMAS , MOLLER ACHIM
IPC: G01N33/50 , A61K38/57 , A61K45/00 , A61P15/00 , A61P15/08 , C12N9/64 , C12N15/09 , C12Q1/37 , G01N33/15 , C12N9/00
Abstract: The invention relates to a novel mammalian calpain CAPN11, to the synthesis and to the use thereof.
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公开(公告)号：HU0004027A2
公开(公告)日：2001-03-28
申请号：HU0004027
申请日：1998-08-19
Applicant: BASF AG
Inventor： BOEHM THOMAS , DEAR NEIL T
IPC: C12N15/09 , A61K31/7105 , A61K38/00 , A61K45/00 , A61K48/00 , A61P9/00 , A61P25/00 , A61P25/28 , A61P29/00 , A61P35/00 , A61P37/00 , A61P37/08 , C07K14/81 , C12N9/64 , C12Q1/37 , C12N9/00
Abstract: The invention relates to new tissue-specific calpaines and their production. The invention also relates to a method for screening for new calpaine inhibitors and their use.
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