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公开(公告)号:TR200102337T2
公开(公告)日:2001-12-21
申请号:TR200102337
申请日:1999-05-10
Applicant: BASF AG
Inventor: RIECHERS HARTMUT , SIMON JOACHIM , HOENN ARTHUR , KRAMER ANDREAS , FUNKE FRANK , SIEGEL WOLFGANG , NUEBLING CHRISTOPH
IPC: B01J23/755 , C07B55/00 , C07B57/00 , C07B61/00 , C07C209/68 , C07C209/88 , C07C211/03 , C07C213/02 , C07C213/08 , C07C217/08 , C07C9/68
Abstract: A process for the preparation of racemic amines of the formula I where R1 and R2 are different and R1, R2, R3 are alkyl, cycloalkyl, arylalkyl, aryl, heteroaryl and heterocyclic radicals and R3 can also be hydrogen, where the radicals can bear substituents selected from the group consisting of alkyl, cycloalkyl, alkoxy, aryloxy, amino, alkylamino and dialkylamino, which comprises simultaneously reacting in situ the corresponding optically active amine I and the secondary alcohol of the formula II and/or the unsymmetrical ketone of the formula III and the amine of the formula R3NH2 in the presence of hydrogen and a hydrogenation catalyst or dehydrogenation catalyst at elevated temperature.