公开(公告)号：DE59802891D1

公开(公告)日：2002-03-14

申请号：DE59802891

申请日：1998-02-09

Applicant: BASF AG

Inventor： DINGLER CHRISTOPH ,  HOLMAN JOHN

IPC: C12N9/02 ,  C07D487/04 ,  C12P17/18 ,  E03D7/00 ,  E04H1/12

Abstract: A process for preparing enantiomerically pure alcohols of the formula I (Ia or Ib)where the substituents have the following meanings:R1hydrogen or substituted or unsubstituted C1-C6-alkyl, C1-C6-alkoxy or C1-C6-alkanoyl,R2 and R3independently of one another hydrogen or substituted or unsubstituted C1-C6-alkyl, C1-C6-alkoxy, C1-C6-alkanoyl, C1-C6-alkylthio, C1-C6-alkylsulfinyl or C1-C6-alkylsulfonyl,R4substituted or unsubstituted C1-C6-alkyl, C3-C8-cycloalkyl,which comprises reducing compounds of the formula II where the substituents R1 to R4 have the abovementioned meanings in aqueous solution in the presence of a carbon source and of a microorganism or of a reducing agent, of a cofactor and of an enzyme, to compounds of the formula I.