公开(公告)号：DE19548317A1

公开(公告)日：1997-06-26

申请号：DE19548317

申请日：1995-12-22

Applicant: BASF AG

Inventor： STEUERLE ULRICH DR ,  PROLL THEO DR ,  HUELTENSCHMIDT WILFRIED

IPC: C07D203/02

Abstract: Preparation of aziridines involves reacting compounds of formula (I) X-C(R )(R )-C(R )(R )-NHR (I),where R - R = H, 1-8C alkyl or aryl ; R = R , benzyl, 1-8C hydroxyalkyl or 1-8C aminoalkyl ; X = -OSO3H, -OSO2-R, halogen or -O-CO-R ;R = alkyl or aryl; and R = H or 1-8C alkyl, with aqueous alkali(ne earth) metal bases at 80 - 280 deg C and up to 100 bar. The reaction is carried out in at least two reactors located one after the other in a cascade, so that the conversion rate of (I) in each reactor is 20 - 90 % and the aziridines are removed from the reaction mixture downstream of each reactor.