Production of secondary amines from nitriles

    公开(公告)号:DE19756947A1

    公开(公告)日:1999-06-24

    申请号:DE19756947

    申请日:1997-12-22

    Applicant: BASF AG

    Abstract: Process for preparing amines of formula X(CH2NHR)n (I) comprises reacting a nitrile of formula X(CN)n (II) with a primary amine of formula RNH2 and hydrogen at 50-250 deg C and 5-350 bar in the presence of a catalyst comprising 0.1-10 wt.% Pd on a support. R = 1-200C alkyl, 3-8C cycloalkyl, 4-20C alkylcycloalkyl, 4-20C cycloalkylalkyl, 2-20C alkoxyalkyl, aryl, 7-20C alkylaryl, 7-20C aralkyl, 2-8C hydroxyalkyl, 2-8C mercaptoalkyl or 8-20C aryloxyalkyl, or R+R = saturated or unsaturated 2-6C alkylene, optionally interrupted by O or N and optionally mono-, di- or trisubstituted by 1-4C alkyl; X = an n-valent 1-20C alkane, 2-20C alkene or 3-8C cycloalkane residue optionally substituted by 1-20C alkyl, 3-8C cycloalkyl, 4-20C alkylcycloalkyl, 4-20C cycloalkylalkyl, 2-20C alkoxyalkyl, aryl, 7-20C alkylaryl, 7-20C aralkyl, 1-20C alkoxy, OH, 1-20C hydroxyalkyl, NH2, 1-20C alkylamino, 2-20C dialkylamino, 2-12C alkenylamino, 3-8C cycloalkylamino, arylamino, diarylamino, aryl-(1-8C alkyl)amino, halogen, SH, 2-20C alkenyloxy, 3-8C cycloalkoxy, aryloxy or 2-8C alkoxycarbonyl; and n = 1-4.

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