公开(公告)号：RU2190468C2

公开(公告)日：2002-10-10

申请号：RU99101934

申请日：1997-06-17

Applicant: BASF AG

Inventor： KHAJNEKE DANIEL ,  MAJSNER RUPREKHT ,  KHESSE MIKHAEL ,  MEHRKL ROBERT

IPC: B01J21/04 ,  B01J23/72 ,  B01J23/89 ,  B01J32/00 ,  B01J35/10 ,  B01J37/04 ,  C07C45/00

公开(公告)号：RU2214393C2

公开(公告)日：2003-10-20

申请号：RU99120672

申请日：1998-02-20

Applicant: BASF AG

Inventor： BEKKER RAJNER ,  EHLLER KARSTEN ,  LANGENZIPEN KHANS-VERNER ,  KHESSE MIKHAEL

IPC: C07C211/51 ,  A61K9/12 ,  B01J21/16 ,  C07B61/00 ,  C07C209/54 ,  C07C209/68 ,  C07C209/78 ,  C07C211/50 ,  C07C211/54

Abstract: FIELD: industrial organic synthesis. SUBSTANCE: mixtures of 4,4'- and 2,4'-isomers of aromatic polyamines of general formula: , where A and B denote phenylene radicals having 1,4-substituents independent from each other and selected from (C1- C20)-alkyl radicals and halogen atoms, with elevated content of 4,4'-isomers are obtained by reaction of o- toluidine with formaldehyde or its precursor at 130-170 C in presence of heterogeneous interaction catalyst selected from group comprising (i) one or several oxides of group 3-10 elements excepting vanadium oxides, which can be acid activated; (ii) if necessary, acid-activated clay doped by impregnation or ion-exchange with at least one group 2-13 elements; and (iii) one or several optionally acid activated stratified silicates with acidity below pKa = 1.5. EFFECT: increased selectivity of reaction. 6 cl, 6 tbl, 14 ex