Abstract:
Title compd. (I; R1,R2,R3 = H, unsubstituted aliphatic group, cycloaromatic group, halogen, alkyl, alkoxy, haloalkoxy, alkylsulfonyl, dialkylamidosulfonyl substituted aliphatic group, cyclo aliphatic group; R1 = dialkylamino; R3 = halogen, trifluoromethyl; R4 = H, alkyl; Y = -CH=, -N= ), useful for protecting corps, were prepd. by cyclization of sulfamates(III) with acid halide or acid anhydride. The sulfamates was prepd. by reacting aminopyridine carboxyamide derives. (II) with SO3, sulfonic chloride or additive of SO3 and organic base in the presence of organic base.
Abstract:
Method for making an aqueous solution of substantially pure salts of 3-isopropyl-2,1,3-benzothiadiazin-(4)-one-2,2-dioxide from a solution of this compound in an organic solvent.
Abstract:
A process for preparing 3-isopropyl-1H-2,1,3-benzothiadiazin-4 (3H)-one 2,2-dioxide (I) or a salt of Iwhich comprises reacting anthranilic isopropylamide IIsimultaneously with sulfur trioxide or chlorosulfonic acid in the presence of an organic base or with adducts of sulfur trioxide and organic basesandphosphorus oxychloride at from 50° C. to the reflux temperature, followed, if appropriate, by conversion into its salts, is described.
Abstract:
The invention relates to a method for the preparation of the compound given above in the title or its salt with the formula By the method isopropylamide of the anthranylic acid with the formula reacts simultaneously with sulpur trioxide or chlorsulphonic acid in the presence of an organic base, or with adducts of sulphur trioxide and organic bases and with phosphorus oxychloride at temperatures ranging from 50 deg.C to the boiling temperature under influx. Then optionally the product can be converted into its salt. 10 claims