公开(公告)号：CA2602380C

公开(公告)日：2011-02-08

申请号：CA2602380

申请日：1998-08-18

Applicant: BASF AG

Inventor： CURTZE JUERGEN ,  MORSCHHAEUSER GERD ,  STUMM KARL-OTTO ,  ALBERT GUIDO ,  REICHERT GUNTHER ,  SIMON WERNER ,  WALDECK ANDREAS ,  COTTER HENRY VAN TUYL ,  REHNIG ANNEROSE EDITH ELISE

IPC: C07C65/21 ,  C07C51/363

Abstract: Disclosed is a process for the preparation of a compound of the general formula (III): (see formula III) wherein: R1 represents a halogen atom or a C1-10-alkyl group; R2 represents a halogen atom; Y represents a leaving group or a hydroxy group; and n is an integer from 0 to 3, comprising reacting a compound of the general formula (VI): (see formula VI) wherein: R1 and n are as defined above; and R" represents H, with a halogenating agent. Also disclosed is a compound of formula (IIIA): (see formula IIIA) wherein R1 represents an alkyl group.

公开(公告)号：DE69628712T2

公开(公告)日：2004-04-29

申请号：DE69628712

申请日：1996-10-16

Applicant: BASF AG ,  AMERICAN CYANAMID CO

Inventor： KRUMMEL GUENTHER ,  STUMM KARL-OTTO ,  PEES KLAUS-JUERGEN ,  LIERS PETER HEINZ RUDI

IPC: C07D487/04

Abstract: An effective and efficient process for the preparation of a dihaloazolopyrimidine having the structural formula In this process, a malonic acid ester is reacted with a heterocyclylamine to form an intermediate salt, which optionally may be acidified to form a dihydroxyazolopyrimidine; the salt or the dihydroxyazolopyrimidine is then halogenated.

公开(公告)号：SI0897904T1

公开(公告)日：2002-06-30

申请号：SI9830091

申请日：1998-08-18

Applicant: BASF AG

Inventor： CURTZE JUERGEN ,  MORSCHHAEUSER GERD ,  STUMM KARL-OTTO ,  ALBERT GUIDO ,  REICHERT GUNTHER ,  SIMON WERNER ,  WALDECK ANDREAS ,  COTTER HENRY VAN TUYL ,  REHNIG ANNEROSE EDITH ELISE

IPC: A01N35/04 ,  C07C45/46 ,  C07C45/68 ,  C07C45/70 ,  C07C49/84 ,  C07C51/347 ,  C07C51/363 ,  C07C51/60 ,  C07C65/21 ,  C07C67/307 ,  C07C67/343 ,  C07C69/92 ,  C07C205/45

公开(公告)号：DE69803907T2

公开(公告)日：2002-06-27

申请号：DE69803907

申请日：1998-08-18

Applicant: BASF AG

Inventor： CURTZE JUERGEN ,  MORSCHHAEUSER GERD ,  STUMM KARL-OTTO ,  ALBERT GUIDO ,  REICHERT GUNTHER ,  SIMON WERNER ,  WALDECK ANDREAS ,  COTTER HENRY VAN TUYL ,  REHNIG ANNEROSE EDITH ELISE

IPC: A01N35/04 ,  C07C45/46 ,  C07C45/67 ,  C07C45/68 ,  C07C45/70 ,  C07C45/71 ,  C07C49/84 ,  C07C65/21 ,  C07C65/24 ,  C07C205/45 ,  C07C51/347 ,  C07C51/363 ,  C07C51/60 ,  C07C67/307 ,  C07C67/343

公开(公告)号：SI0770615T1

公开(公告)日：2003-12-31

申请号：SI9630630

申请日：1996-10-16

Applicant: BASF AG

Inventor： KRUMMEL GUENTHER ,  STUMM KARL-OTTO ,  PEES KLAUS-JUERGEN ,  LIERS PETER HEINZ RUDI

IPC: C07D487/04

Abstract: An effective and efficient process for the preparation of a dihaloazolopyrimidine having the structural formula In this process, a malonic acid ester is reacted with a heterocyclylamine to form an intermediate salt, which optionally may be acidified to form a dihydroxyazolopyrimidine; the salt or the dihydroxyazolopyrimidine is then halogenated.

公开(公告)号：AT243211T

公开(公告)日：2003-07-15

申请号：AT96307528

申请日：1996-10-16

Applicant: BASF AG

Inventor： KRUMMEL GUENTHER ,  STUMM KARL-OTTO ,  PEES KLAUS-JUERGEN ,  LIERS PETER HEINZ RUDI

IPC: C07D487/04 ,  C07D249/00 ,  C07D239/00

Abstract: An effective and efficient process for the preparation of a dihaloazolopyrimidine having the structural formula In this process, a malonic acid ester is reacted with a heterocyclylamine to form an intermediate salt, which optionally may be acidified to form a dihydroxyazolopyrimidine; the salt or the dihydroxyazolopyrimidine is then halogenated.

公开(公告)号：DK0770615T3

公开(公告)日：2003-07-14

申请号：DK96307528

申请日：1996-10-16

Applicant: BASF AG

Inventor： KRUMMEL GUENTHER ,  STUMM KARL-OTTO ,  PEES KLAUS-JUERGEN ,  LIERS PETER HEINZ RUDI

IPC: C07D487/04

Abstract: An effective and efficient process for the preparation of a dihaloazolopyrimidine having the structural formula In this process, a malonic acid ester is reacted with a heterocyclylamine to form an intermediate salt, which optionally may be acidified to form a dihydroxyazolopyrimidine; the salt or the dihydroxyazolopyrimidine is then halogenated.

公开(公告)号：PT897904E

公开(公告)日：2002-08-30

申请号：PT98306583

申请日：1998-08-18

Applicant: BASF AG

Inventor： CURTZE JURGEN ,  ALBERT GUIDO ,  COTTER HENRY VAN TUYL ,  MORSCHHAEUSER GERD ,  STUMM KARL-OTTO ,  REICHERT GUNTHER ,  SIMON WERNER ,  WALDECK ANDREAS ,  REHNIG ANNEROSE EDITH ELISE

IPC: A01N35/04 ,  C07C45/46 ,  C07C45/67 ,  C07C45/68 ,  C07C45/70 ,  C07C45/71 ,  C07C49/84 ,  C07C65/21 ,  C07C65/24 ,  C07C205/45 ,  C07C51/347 ,  C07C51/363 ,  C07C51/60 ,  C07C67/307 ,  C07C67/343 ,  C07C69/92

公开(公告)号：DE69628712D1

公开(公告)日：2003-07-24

申请号：DE69628712

申请日：1996-10-16

Applicant: BASF AG ,  AMERICAN CYANAMID CO

Inventor： KRUMMEL GUENTHER ,  STUMM KARL-OTTO ,  PEES KLAUS-JUERGEN ,  LIERS PETER HEINZ RUDI

IPC: C07D487/04

Abstract: An effective and efficient process for the preparation of a dihaloazolopyrimidine having the structural formula In this process, a malonic acid ester is reacted with a heterocyclylamine to form an intermediate salt, which optionally may be acidified to form a dihydroxyazolopyrimidine; the salt or the dihydroxyazolopyrimidine is then halogenated.

公开(公告)号：ES2172864T3

公开(公告)日：2002-10-01

申请号：ES98306583

申请日：1998-08-18

Applicant: BASF AG

Inventor： CURTZE JUERGEN ,  MORSCHHAEUSER GERD ,  STUMM KARL-OTTO ,  ALBERT GUIDO ,  REICHERT GUNTHER ,  SIMON WERNER

IPC: A01N35/04 ,  C07C45/46 ,  C07C45/67 ,  C07C45/68 ,  C07C45/70 ,  C07C45/71 ,  C07C49/84 ,  C07C65/21 ,  C07C65/24 ,  C07C205/45 ,  C07C51/347 ,  C07C51/363 ,  C07C51/60 ,  C07C67/307 ,  C07C67/343 ,  C07C69/92