公开(公告)号：WO2007071581A3

公开(公告)日：2008-01-10

申请号：PCT/EP2006069515

申请日：2006-12-11

Applicant: BASF AG ,  KOLTER KARL ,  WICHTNER MARCUS ,  SCHOENHERR MICHAEL ,  MITTWOLLEN JAN-PETER

Inventor： KOLTER KARL ,  WICHTNER MARCUS ,  SCHOENHERR MICHAEL ,  MITTWOLLEN JAN-PETER

IPC: A61K9/00 ,  A61K9/20

CPC classification number: A61K9/0056 ,  A61K9/2018

Abstract: The invention relates to a pharmaceutical formulation in the form of agglomerates containing a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of cross-linked polyvinylpyrrolidone, c) 1 - 15 % by weight of water-insoluble, film-forming polymers, d) 0 - 15 % by weight of water-soluble polymers, and e) 0 - 15 % by weight of other pharmaceutically suitable adjuvants, the sum of components a) to e) adding up to 100 % by weight.

Abstract translation: 在含有糖或糖醇的）60-97重量％的聚集体形式的药物制剂，b）中1 - 25重量％的交联聚乙烯吡咯烷酮，C）1 - 15重量％的水不溶性，成膜聚合物d）0 - 15 重量的水溶性聚合物的.-％，和e）0 - 15重量％的其它药学上常用的赋形剂，其中组分的总和a）至e）为100重量％（重量）。

公开(公告)号：CA2634357A1

公开(公告)日：2007-06-28

申请号：CA2634357

申请日：2006-12-11

Applicant: BASF AG

Inventor： MITTWOLLEN JAN-PETER ,  SCHOENHERR MICHAEL ,  WICHTNER MARCUS ,  KOLTER KARL

IPC: A61K9/00 ,  A61K9/20

Abstract: A pharmaceutical formulation in the form of agglomerates comprising a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of crosslinked polyvinylpyrrolidone, c) 1-15% by weight of water-insoluble, film-forming polymers, d) 0-15% by weight of water-soluble polymers and e) 0-15% by weight of further pharmaceutically customary excipients, the sum of the components a) to e) being 100% by weight.

公开(公告)号：AU2005211525A1

公开(公告)日：2006-03-30

申请号：AU2005211525

申请日：2005-09-14

Applicant: BASF AG

Inventor： KOLTER KARL ,  EINIG HEINZ ,  MEYER KATHRIN ,  WICHTNER MARCUS

IPC: A61K47/38 ,  A61K31/137 ,  A61K47/04 ,  A61K47/12 ,  A61K47/36 ,  A61P11/06 ,  A61P25/00 ,  A61P25/04

Abstract: A solid oral pharmaceutical dosage form of a sympathomimetic with impeded extractability of the sympathomimetic, comprising I) a sympathomimetic (component I) II) an excipient mixture (component II) composed of a) 5 to 50% by weight of hydroxyalkylcelluloses or alkylcelluloses or mixtures thereof b) 5 to 70% by weight of xant

公开(公告)号：CA2515626A1

公开(公告)日：2006-03-15

申请号：CA2515626

申请日：2005-08-10

Applicant: BASF AG

Inventor： WICHTNER MARCUS ,  KOLTER KARL ,  MEYER KATHRIN ,  EINIG HEINZ

IPC: A61K9/20 ,  A61K47/02 ,  A61K47/38

Abstract: A solid oral pharmaceutical dosage form of a sympathomimetic with impede d extractability of the sympathomimetic, comprising I) a sympathomimetic (component I) II) an excipient mixture (component II) composed of a) 5 to 50% by weight of hydroxyalkylcelluloses or alkylcelluloses or mixtur es thereof b) 5 to 70% by weight of xanthan c) 5 to 50% by weight of an alkaline earth metal salt of a C10-C30 fatty aci d d) 10 to 70% by weight of an alkali metal or alkaline earth metal salt of a mineral acid, of a sulfonic acid or of a C2-C6 carboxylic acid or mixtures thereof, where the total of components a) to d) is 100% by weight, where the ratio of active ingredient to excipient mixture II) is from 1:2 to 3:1 by weight.