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公开(公告)号：WO2002072047A2
公开(公告)日：2002-09-19
申请号：PCT/EP2002/001802
申请日：2002-02-20
Applicant: BASF AKTIENGESELLSCHAFT , MEFFERT, Helmut , SANNER, Axel , TIEFENSEE, Kristin , KOTHRADE, Stephan
Inventor： MEFFERT, Helmut , SANNER, Axel , TIEFENSEE, Kristin , KOTHRADE, Stephan
IPC: A61K7/06
CPC classification number: A61Q19/00 , A61K8/90 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/10
Abstract: Die vorliegende Erfindung betrifft kosmetische oder pharmazeutische Mittel mit flüssiger bis gelförmiger Konsistenz, die wenigstens ein Copolymer enthalten, das mindestens ein N-Vinyllactam sowie wenigstens ein ethylenisch ungesättigtes Monomer mit einem längerkettigen Alkyl- oder Alkenylrest einpolymerisiert enthält. Die Erfindung betrifft weiterhin die Verwendung solcher Copolymere in kosmetischen oder pharmazeutischen Zusammensetzungen.
Abstract translation: 本发明涉及的液体的凝胶状稠度的化妆品或药物组合物，其包含含有至少一种N-乙烯基内酰胺和具有长链烷基或链烯基共聚的至少一种烯属不饱和单体的至少一种共聚物。 本发明还涉及使用在化妆品或药物组合物例如共聚物。
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2.发明授权
公开(公告)号：EP1135109B1
公开(公告)日：2003-04-02
申请号：EP99966909.6
申请日：1999-11-30
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： BERNDL, Gunther , KOTHRADE, Stephan , KESSLER, Thomas , LANGE, Armin , HOFMANN, Jürgen , REINHOLD, Ulrich
IPC: A61K9/16
CPC classification number: B29C47/42 , A61J3/10 , A61J2200/20 , A61K9/1694 , A61K9/2095 , B29B7/485 , B29C47/0021
Abstract: The invention relates to a method for producing solid forms of administration by means of melt extrusion. A polymer binder, at least one pharmaceutical active agent and optionally, other additives are mixed and the mixture is melted in an extruder and then extruded in the form of a continuous plastic product strand. The inventive method is characterised in that the extruder used is a planetary roller extruder (10) which preferably has one central spindle (13) and six planetary spindles (14).
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3.发明公开VERWENDUNG WASSERLÖSLICHER COPOLYMERE ALS WIRKSTOFFE IN KOSMETISCHEN FORMULIERUNGEN 失效使用水基共聚物在化妆品配方中有效成分
公开(公告)号：EP0929285A2
公开(公告)日：1999-07-21
申请号：EP97909334.0
申请日：1997-09-29
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： NIESSNER, Manfred , NILZ, Claudia , HÖSSEL, Peter , KOTHRADE, Stephan , SANNER, Axel
CPC classification number: A61Q5/00 , A61K8/817 , A61Q5/06 , A61Q5/12 , A61Q11/00 , A61Q19/00 , Y10S514/944 , Y10S514/945
Abstract: The present invention relates to the use of water-soluble copolymers consisting of such characteristic structural elements as a) acrylic acid amide of the general formula (I), where R1 et R2 stand, independently of each other, for H, alkyl, cycloalkyl, aryl or aralkyl, and b) units of the general formula (II), where A represents a chemical bond or an alkyl group, the R3 residues stand, independently of each other, for H, alkyl, cycloalkyl, aryl or arakyl or, together with the nitrogen atom to which they are linked, an aromatic or non aromatic five to seven member heterocyclic ring, possibly mono- or polysubstituted, possibly containing one or two more heteroatoms chosen from among O, N or S, and capable of being annelated with another aromatic or non aromatic five to seven member ring, and R4 represents H, alkyl or aralkyl. The invention also pertains to cosmetics containing said polymers.
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4.发明授权
公开(公告)号：EP0930875B1
公开(公告)日：2003-05-07
申请号：EP97942022.1
申请日：1997-09-11
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： BREITENBACH, Jörg , KLEINKE, Andreas , KOTHRADE, Stephan , ROSENBERG, Joerg
CPC classification number: A61K9/2095 , A61K9/2027 , A61K9/2086
Abstract: The present invention relates to a process for producing solid dosage forms by mixing at least one polymer binder, possibly at least one active substance and possibly the usual additives, as well as products derived from this mixture, of which at least one component is added in liquid state.
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5.发明公开
公开(公告)号：EP0930875A2
公开(公告)日：1999-07-28
申请号：EP97942022.0
申请日：1997-09-11
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： BREITENBACH, Jörg , KLEINKE, Andreas , KOTHRADE, Stephan , ROSENBERG, Joerg
CPC classification number: A61K9/2095 , A61K9/2027 , A61K9/2086
Abstract: The present invention relates to a process for producing solid dosage forms by mixing at least one polymer binder, possibly at least one active substance and possibly the usual additives, as well as products derived from this mixture, of which at least one component is added in liquid state.
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Patent Agency Ranking
公开(公告)号：EP1363585A2
公开(公告)日：2003-11-26
申请号：EP02718151.0
申请日：2002-02-20
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： MEFFERT, Helmut , SANNER, Axel , TIEFENSEE, Kristin , KOTHRADE, Stephan
CPC classification number: A61Q19/00 , A61K8/90 , A61Q5/02 , A61Q5/06 , A61Q5/12 , A61Q17/04 , A61Q19/10
Abstract: The invention relates to cosmetic or pharmaceutical agents having a liquid or gel consistency and containing at least one copolymer that, in turn, contains at least one N-vinyl lactam and at least one ethylenically unsaturated monomer with a longer-chain alkyl radical or alkenyl radical, said N-vinyl lactam and monomer being incorporated by polymerization in the copolymer. The invention also relates to the use of copolymers of the aforementioned type in cosmetic or pharmaceutical compositions.
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7.发明授权VERWENDUNG WASSERLÖSLICHER COPOLYMERE ALS WIRKSTOFFE IN KOSMETISCHEN FORMULIERUNGEN 失效使用水基共聚物在化妆品配方中有效成分
公开(公告)号：EP0929285B1
公开(公告)日：2001-11-21
申请号：EP97909334.1
申请日：1997-09-29
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： NIESSNER, Manfred , NILZ, Claudia , HÖSSEL, Peter , KOTHRADE, Stephan , SANNER, Axel
CPC classification number: A61Q5/00 , A61K8/817 , A61Q5/06 , A61Q5/12 , A61Q11/00 , A61Q19/00 , Y10S514/944 , Y10S514/945
Abstract: The present invention relates to the use of water-soluble copolymers consisting of such characteristic structural elements as a) acrylic acid amide of the general formula (I), where R et R stand, independently of each other, for H, alkyl, cycloalkyl, aryl or aralkyl, and b) units of the general formula (II), where A represents a chemical bond or an alkyl group, the R residues stand, independently of each other, for H, alkyl, cycloalkyl, aryl or arakyl or, together with the nitrogen atom to which they are linked, an aromatic or non aromatic five to seven member heterocyclic ring, possibly mono- or polysubstituted, possibly containing one or two more heteroatoms chosen from among O, N or S, and capable of being annelated with another aromatic or non aromatic five to seven member ring, and R represents H, alkyl or aralkyl. The invention also pertains to cosmetics containing said polymers.
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公开(公告)号：EP1035841B1
公开(公告)日：2002-07-24
申请号：EP98965716.8
申请日：1998-11-30
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： KOTHRADE, Stephan , MEFFERT, Helmut , BERNDL, Gunther , ERNST, Andreas , SANNER, Axel
IPC: A61K9/22
CPC classification number: A61K31/421 , A23K20/10 , A23K40/10 , A23K40/20 , A23K40/25 , A23L27/74 , A23L33/10 , A23V2002/00 , A61K9/2027 , A61K9/2095 , A61K31/277 , A23V2200/21 , A23V2250/30 , A23V2250/51088 , A23V2250/5118
Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture and during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is used as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.
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9.发明公开
公开(公告)号：EP1135109A2
公开(公告)日：2001-09-26
申请号：EP99966909.6
申请日：1999-11-30
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： BERNDL, Gunther , KOTHRADE, Stephan , KESSLER, Thomas , LANGE, Armin , HOFMANN, Jürgen , REINHOLD, Ulrich
IPC: A61K9/16
CPC classification number: B29C47/42 , A61J3/10 , A61J2200/20 , A61K9/1694 , A61K9/2095 , B29B7/485 , B29C47/0021
Abstract: The invention relates to a method for producing solid forms of administration by means of melt extrusion. A polymer binder, at least one pharmaceutical active agent and optionally, other additives are mixed and the mixture is melted in an extruder and then extruded in the form of a continuous plastic product strand. The inventive method is characterised in that the extruder used is a planetary roller extruder (10) which preferably has one central spindle (13) and six planetary spindles (14).
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公开(公告)号：EP1035841A1
公开(公告)日：2000-09-20
申请号：EP98965716.8
申请日：1998-11-30
Applicant: BASF AKTIENGESELLSCHAFT
Inventor： KOTHRADE, Stephan , MEFFERT, Helmut , BERNDL, Gunther , ERNST, Andreas , SANNER, Axel
IPC: A61K9/22
CPC classification number: A61K31/421 , A23K20/10 , A23K40/10 , A23K40/20 , A23K40/25 , A23L27/74 , A23L33/10 , A23V2002/00 , A61K9/2027 , A61K9/2095 , A61K31/277 , A23V2200/21 , A23V2250/30 , A23V2250/51088 , A23V2250/5118
Abstract: The invention relates to a method for producing solid dosing forms by mixing at least one polymeric binding agent, at least one active substance, and optional common additives while producing a plastic mixture and during shaping, whereby a copolymer from a N-vinyl lactam and from an copolymerizable monomer with a hydrophobic radical is used as a polymeric binding agent. Dosing forms which slowly release the active substance are obtained in a simple and economical manner.
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