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公开(公告)号:WO2004037386A3
公开(公告)日:2004-07-01
申请号:PCT/EP0306359
申请日:2003-06-17
Applicant: BASF CORP , LISA RUDOLPH ERNEST , ABRAHAM GEORGE
Inventor: LISA RUDOLPH ERNEST , ABRAHAM GEORGE
CPC classification number: B01D39/18 , B01D29/096 , B01D39/1623 , B01D39/2003
Abstract: An index filtration method is disclosed for filtering graft polyol dispersions. The method allows for the rapid filtration of large volumes of graft polyol dispersion in an economical manner. The process can be highly automated. The resulting filtered graft polyol dispersion mainly has particles of 25 microns or smaller and is stable under a variety of conditions for at least 9 weeks.
Abstract translation: 公开了一种用于过滤接枝多元醇分散体的索引过滤方法。 该方法允许以经济的方式快速过滤大体积的接枝多元醇分散体。 该过程可以高度自动化。 所得过滤接枝多元醇分散体主要具有25微米或更小的颗粒,并且在各种条件下稳定至少9周。
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公开(公告)号:WO0232845A3
公开(公告)日:2002-07-25
申请号:PCT/EP0111997
申请日:2001-10-17
Applicant: BASF CORP , PETERSON RODGER E , CANNAN TERRANCE M , LISA RUDOLPH ERNEST
Inventor: PETERSON RODGER E , CANNAN TERRANCE M , LISA RUDOLPH ERNEST
IPC: C07D215/48 , C07C51/41 , C07C59/135 , C07C65/21 , C07D213/64 , C07D213/73 , C07D213/79 , C07C59/68 , C07C63/10 , C07C227/18
CPC classification number: C07C51/412 , C07C59/68 , C07C65/21 , C07C63/10
Abstract: The present invention is a method of producing dry, alkali metal or ammonium carboxylic acid salt particles. In accordance with the invention, a molten carboxylic acid is mixed with a solution of an alkali metal-containing or ammonium-containing alkaline compound and the carboxylic acid and alkaline compound are reacted to form the carboxylic acid salt. Water is then removed from the carboxylic acid salt to produce dry, carboxylic acid salt particles. The feed ratio of the molten carboxylic acid and the alkyline compound is controlled to neutralize the carboxylic acid in the process.
Abstract translation: 本发明是生产干燥的碱金属或铵盐羧酸盐颗粒的方法。 根据本发明,将熔融的羧酸与含碱金属或含铵的碱性化合物的溶液混合,使羧酸和碱性化合物反应形成羧酸盐。 然后从羧酸盐中除去水分以产生干燥的羧酸盐颗粒。 控制熔融羧酸和烷基化合物的进料比以中和过程中的羧酸。
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公开(公告)号:JP2006151980A
公开(公告)日:2006-06-15
申请号:JP2005342508
申请日:2005-11-28
Applicant: Basf Ag , Basf Corp , ビー・エイ・エス・エフ、コーポレーションBASF Corporation , ビーエーエスエフ アクチェンゲゼルシャフトBASF Aktiengesellschaft
Inventor: LISA RUDOLPH ERNEST , QUADIR ANISUL , SCHEPER REBECCA H , GRZESIOWSKI PETER
CPC classification number: A61K9/2031 , A61K9/146 , A61K9/5089 , A61K31/55 , A61K47/34 , B01J2/04
Abstract: PROBLEM TO BE SOLVED: To provide a method for forming a micro-prilled poloxamer used specially in the pharmaceutical manufacturing industry as a dispersant or solubilizer and a vehicle presenting sustained release properties. SOLUTION: The method for forming a micro-prilled poloxamer comprises using spraying gas at a pressure higher than ordinary pressure, a spraying nozzle at high spraying gas temperature and a high feed temperature for reducing poloxamer viscosity, and optionally, sieving after forming prills in a prilling column. The poloxamer prills are specially used in pharmaceutical preparations, being spherical with a nominal average size of preferably 106 μm or less. This method is highly cost-effective, being rapid in preparation. COPYRIGHT: (C)2006,JPO&NCIPI
Abstract translation: 要解决的问题:提供一种用于形成药物制造工业中特别用作分散剂或增溶剂的微粒化泊洛沙姆的方法和具有持续释放性质的载体。 解决方案:形成微孔泊洛沙姆的方法包括使用高于普通压力的喷雾气体,高喷雾气体温度下的喷雾喷嘴和降低泊洛沙姆粘度的高进料温度,以及任选地在成型后进行筛分 饲养在一个造血柱。 泊洛沙姆颗粒剂特别用于药物制剂中,为平均粒径优选为10μm以下的球形。 这种方法是非常具有成本效益的,正在迅速准备。 版权所有(C)2006,JPO&NCIPI
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公开(公告)号:CA2425567C
公开(公告)日:2010-12-21
申请号:CA2425567
申请日:2001-10-17
Applicant: BASF CORP
Inventor: PETERSON RODGER E , CANNAN TERRANCE M , LISA RUDOLPH ERNEST
IPC: C07C51/41 , C07D215/48 , C07C59/135 , C07C59/68 , C07C63/10 , C07C65/21 , C07C227/18 , C07D213/64 , C07D213/73 , C07D213/79
Abstract: The present invention is a method of producing dry, alkali metal or ammonium carboxylic acid salt particles. In accordance with the invention, a molten carboxylic acid is mixed with a solution of an alkali metal-containing or ammonium-containing alkaline compound and the carboxylic acid and alkaline compound are reacted to form the carboxylic acid salt. Water is then removed from the carboxylic acid salt to produce dry, carboxylic acid salt particles. The feed ratio of the molten carboxylic acid and the alkyline compound is controlled to neutralize the carboxylic acid in the process.
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公开(公告)号:BR0315379A
公开(公告)日:2005-08-23
申请号:BR0315379
申请日:2003-06-17
Applicant: BASF CORP
Inventor: LISA RUDOLPH ERNEST , ABRAHAM GEORGE
Abstract: An index filtration method is disclosed for filtering graft polyol dispersions. The method allows for the rapid filtration of large volumes of graft polyol dispersion in an economical manner. The process can be highly automated. The resulting filtered graft polyol dispersion mainly has particles of 25 microns or smaller and is stable under a variety of conditions for at least 9 weeks.
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公开(公告)号:BR0114684A
公开(公告)日:2004-01-13
申请号:BR0114684
申请日:2001-10-17
Applicant: BASF CORP
Inventor: PETERSON RODGER E , CANNAN TERRANCE M , LISA RUDOLPH ERNEST
IPC: C07D215/48 , C07C51/41 , C07C59/135 , C07C65/21 , C07D213/64 , C07D213/73 , C07D213/79 , C07C63/10 , C07C59/68 , C07C227/18
Abstract: The present invention is a method of producing dry, alkali metal or ammonium carboxylic acid salt particles. In accordance with the invention, a molten carboxylic acid is mixed with a solution of an alkali metal-containing or ammonium-containing alkaline compound and the carboxylic acid and alkaline compound are reacted to form the carboxylic acid salt. Water is then removed from the carboxylic acid salt to produce dry, carboxylic acid salt particles. The feed ratio of the molten carboxylic acid and the alkaline compound is controlled to neutralize the carboxylic acid in the process.
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公开(公告)号:SK281625B6
公开(公告)日:2001-05-10
申请号:SK8596
申请日:1994-07-09
Applicant: BASF CORP
Inventor: JAGER KARL-FRIEDRICH , KILBRIDE TERENCE , LISA RUDOLPH ERNEST
Abstract: The present invention provides hygroscopic plant growth regulator formulations in solid forms and associated methods of making the powders and tablets. The most preferred formulation uses an effective amount of an N,N-dimethyl-piperidinium salt.
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公开(公告)号:IN178906B
公开(公告)日:1997-07-19
申请号:IN574MA1994
申请日:1994-06-29
Applicant: BASF CORP
Inventor: JAGER KARL-FRIEDIRCH , KILBRIDE TERENCE , LISA RUDOLPH ERNEST
IPC: A01N43/00
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公开(公告)号:AU679773B2
公开(公告)日:1997-07-10
申请号:AU7385294
申请日:1994-07-09
Applicant: BASF CORP
Inventor: JAGER KARL-FRIEDRICH , KILBRIDE TERENCE JR , LISA RUDOLPH ERNEST
Abstract: The present invention provides hygroscopic plant growth regulator formulations in solid forms and associated methods of making the powders and tablets. The most preferred formulation uses an effective amount of an N,N-dimethyl-piperidinium salt.
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公开(公告)号:FI960269A0
公开(公告)日:1996-01-19
申请号:FI960269
申请日:1996-01-19
Applicant: BASF CORP
Inventor: JAEGER KARL-FRIEDRICH , KILBRIDE JR TERENCE , LISA RUDOLPH ERNEST
Abstract: The present invention provides hygroscopic plant growth regulator formulations in solid forms and associated methods of making the powders and tablets. The most preferred formulation uses an effective amount of an N,N-dimethyl-piperidinium salt.
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