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公开(公告)号：WO2020079114A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/078147
申请日：2019-10-17
Applicant: BASF SE
Inventor： PUHL, Michael , WLOCH, Sebastian , OEDMAN, Peter , LETZEL, Anne-Catrin , SCHROEDER, Hartwig , MALISZ, Jacek , SEIBERT-LUDWIG, Daniel , KAPPERT, Emiel Jan , WONG, Chung Huan , BARROS GROSS, Michael , VIERTELHAUS, Martin
Abstract: The present invention relates to a method for obtaining crystalline 2'-fucosyllactose from a 2'-FL raw material, which contains 2'-FL as a main constituent and at least 0.5% by weight, frequently at least 1% by weight, in particular at least 2% by weight, more particularly at least 5% by weight, and especially at least 8% by weight,based on the total amount of mono-and oligosaccharides in the raw material, of one or more mono- or oligosaccharides different from 2'-FL, where the method comprises a)providing a solution of the 2'-FL raw material in water, which does not contain more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents, based on the total amount of water; b) effecting the crystallization of 2'-FL from the solution provided in step a) by inducing conditions of a controlled super saturation in the solution; and c) separating crystalline 2'-FL from the mother liquor, and where during controlled supersaturation in step b) not more than 10% by weight, preferably not more than 7% by weight, more preferably not more than 5% by weight of organic solvents are present, based on the total amount of water present during step b).
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公开(公告)号：WO2020079146A1
公开(公告)日：2020-04-23
申请号：PCT/EP2019/078209
申请日：2019-10-17
Applicant: BASF SE
Inventor： VIERTELHAUS, Martin , PUHL, Michael , WLOCH, Sebastian , OEDMAN, Peter , LETZEL, Anne-Catrin , SCHROEDER, Hartwig , MALISZ, Jacek , SEIBERT-LUDWIG, Daniel , KAPPERT, Emiel Jan , WONG, Chung Huan , BARROS GROSS, Michael
Abstract: Crystalline form II of 2'-O-fucosyl lactose having an X-ray powder diffraction pattern comprising three reflections at 2θ angles (13.65 ± 0.20)°, (16.98 ± 0.20)° and (18.32 ± 0.20)°, determined at a temperature of 25 °C with Cu-Kα 1,2 radiation having a wavelength of 0.15419 nm, said crystalline form exhibiting an α:β anomeric ratio in the range of from 4:60 to 60:40, determined by 13 C-NMR.
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公开(公告)号：EP3867258A1
公开(公告)日：2021-08-25
申请号：EP19786589.2
申请日：2019-10-17
Applicant: BASF SE
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