公开(公告)号：MY191536A

公开(公告)日：2022-06-29

申请号：MYPI2017000426

申请日：2015-09-30

Applicant: BASF SE

Inventor： DR FREYER STEPHAN ,  DR BRAUN MICHAEL ,  DAEUWEL JUERGEN ,  DR OEDMAN PETER ,  DR BALDENIUS KAI-UWE ,  DR KLEINER MATTHIAS ,  DR BUDDE MICHAEL

IPC: C12P13/02

Abstract: The present invention relates to means and methods for producing an amide compound from a nitrile compound with less acrylic acid as by- product using a Nitrile hydratase (NHase) and Amidase producing microorganism as biocatalyst. Also provided is an aqueous amide compound obtained by the methods of the invention as well as a composition comprising acrylamide or polyacrylamide as well as a dried microorganism exhibiting a NHase/Amidase activity ratio of at least 400 when being brought into contact with a nitrile compound to convert said nitrile compound into an amide compound.