公开(公告)号：WO2008031780A3

公开(公告)日：2008-06-26

申请号：PCT/EP2007059436

申请日：2007-09-10

Applicant: BASF SE ,  KOLTZENBURG SEBASTIAN ,  BECHTLOFF BERND ,  VAN GELDER RICHARD ,  FRANKE DIRK

Inventor： KOLTZENBURG SEBASTIAN ,  BECHTLOFF BERND ,  VAN GELDER RICHARD ,  FRANKE DIRK

IPC: A61K9/16 ,  B01F3/08 ,  B65G53/30

CPC classification number: A61K9/1682

Abstract: The invention relates to a method for producing fine-particle dispersions of a chemical compound which is poorly soluble in a dispersant, by the turbulent intermixing of at least two liquid flows described as medium A and medium B, of which at least the liquid flow described as medium A contains the chemical compound to be dispersed or a precursor thereof, in a mixing device provided with at least two inlets and an outlet. The liquid flows are supplied in such a way that the angle between the longitudinal axes of a volume flow of medium A and a volume flow of medium B is between 10° and 170°, and the volume flows have different surface cross-sections.

Abstract translation: 一种用于通过至少两个，称为培养基A和培养基B液体流，其中的一个的湍流混合产生微溶的细碎分散体中的分散剂的化学化合物的方法的至少一个中，被称为介质含有待分散的化学化合物或其前体的液体流，在与 至少两个入口开口和排出混合装置被提供，其中液体流被供给，使得介质的体积流量和介质B的体积流量的纵向轴线之间的角度为10°至170°，并且该体积流具有不同的表面的横截面。

公开(公告)号：ES2291541T3

公开(公告)日：2008-03-01

申请号：ES02804219

申请日：2002-12-03

Applicant: BASF SE

Inventor： KLOPP INGO ,  BOGENSTATTER THOMAS ,  FRANKE DIRK

IPC: C07C51/41 ,  C07C20060101 ,  C07C63/00 ,  C07C63/04 ,  C07C63/08

Abstract: Procedimiento para la obtención de sales amónicas de ácidos carboxílicos aromáticos mediante reacción de un ácido carboxílico aromático con amoniaco en un disolvente aprótico, caracterizado porque la reacción se lleva a cabo en un recipiente cerrado, introduciéndose en el recipiente continuamente una disolución de ácido carboxílico aromático en el disolvente aprótico, alimentándose amoniaco gaseoso de tal manera que, en el espacio gasométrico del recipiente, se mantiene una presión parcial de amoniaco en el intervalo de 0, 1 a 3 bar, y se descarga una suspensión de sal amónica en el disolvente aprótico.

公开(公告)号：AU2001295475B2

公开(公告)日：2006-05-25

申请号：AU2001295475

申请日：2001-08-16

Applicant: BASF SE

Inventor： FRANKE DIRK ,  THERRE JORG ,  BURKART KIRSTEN ,  SENDHOFF NORBERT ,  MUNZINGER MANFRED ,  DROGEMULLER MICHAEL ,  SCHUTZ FRANZ ,  WECK ALEXANDER ,  ISAK HEINZ

IPC: C07D285/34 ,  A01N25/12 ,  A01N43/88

Abstract: Described is a process for the preparation of a particulate tetrahydro-3,5-dimethyl-1,3,5-thiadiazine-2-thione product by combining a first aqueous solution comprising methylammonium N-methyldithiocarbamate with a second aqueous solution comprising formaldehyde, followed by separation and drying of the resulting solid, which comprises combining the first and the second aqueous solutions in such a way that the ratio between the concentrations of dithiocarbamate functions and of formaldehyde is essentially constant in the reaction mixture over time during the duration of the reaction.