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公开(公告)号:MX378055B
公开(公告)日:2025-03-10
申请号:MX2016013573
申请日:2016-10-14
Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC , BASF SE
Inventor: UMALI ANNA MALVEDA , DOYOG CECILLE EBUENGA , MENG CHARLES , PALMER CHIRSTOPHER , MICULKA CHRISTIAN , BASTIAANNS HENRICUS MARIA MARTINUS , SOLL MARK , POHLMAN MATTHIAS , PAULINI RALPH , COSARE RHOEL SUIZA , THOMPSON SARAH , SORGEL SEBASTIAN , HOKAMA TAKEO
Abstract: La presente invención proporciona usos de compuestos de aril alquil malononitrilo de la fórmula (I), o sales veterinariamente aceptables de los mismos, para controlar y prevenir infestaciones de parásitos en animales. La invención también proporciona métodos para controlar y prevenir la infestación de parásitos en animales que comprenden administrar una cantidad efectiva de por lo menos un compuesto de aril alquil malononitrilo de la fórmula (I), o una sal veterinariamente aceptable del mismo, al animal.
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公开(公告)号:CA2945766A1
公开(公告)日:2015-10-22
申请号:CA2945766
申请日:2015-04-17
Applicant: MERIAL INC , BASF SE
Inventor: MENG CHARLES , MICULKA CHRISTIAN , SOLL MARK , PAULINI RALPH , POHLMAN MATTHIAS , SORGEL SEBASTIAN , BASTIAANNS HENRICUS MARIA MARTINUS , THOMPSON SARAH , EBUENGA DOYOG CECILLE , MALVEDA UMALI ANNA , SUIZA COSARE RHOEL , PALMER CHRISTOPHER , HOKAMA TAKEO
IPC: A61K31/277 , A61P33/14
Abstract: The present invention provides uses of aryl alkyl malononitrile compounds of formula (I), or veterinarily acceptable salts thereof, for controlling and preventing parasite infestations in animals. The invention also provides methods for controlling and preventing parasite infestation in animals comprising administering an effective amount of at least one aryl alkyl malononitrile compound of formula (I), or a veterinarily acceptable salt thereof, to the animal.
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公开(公告)号:CA2888390A1
公开(公告)日:2014-05-01
申请号:CA2888390
申请日:2013-10-22
Applicant: BASF SE
Inventor: PAULINI RALPH , POHLMAN MATTHIAS , SORGEL SEBASTIAN , BASTIAANS HENRICUS MARIA MARTINUS , THOMPSON SARAH , EBUENGA DOYOG CECILLE , MALVEDA UMALI ANNA , SUIZA COSARE RHOEL , PALMER CHRISTOPHER , HOKAMA TAKEO
Abstract: The invention relates to the use of a compound of formula (I) or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification.
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公开(公告)号:BRPI0713040A2
公开(公告)日:2012-04-17
申请号:BRPI0713040
申请日:2007-06-22
Applicant: BASF SE
Inventor: POHLMAN MATTHIAS , HOFMANN MICHAEL , BASTIAANS HENRICUS MARIA MARTINUS , RACK MICHAEL , CULBERTSON DEBORAH L , OLOUMI-SADEGHI HASSAN , HOKAMA TAKEO , PALMER CHRISTOPHER
IPC: C07C255/10 , A01N37/34
Abstract: Compounds of formula (I) wherein the symbols have the meaning given in the specification, as well as processes for preparing the compounds (I), pesticidal compositions and synergistic mixtures comprising compounds (I), methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula (I), and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula (I).
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公开(公告)号:NZ707308A
公开(公告)日:2018-09-28
申请号:NZ70730813
申请日:2013-10-22
Applicant: BASF SE
Inventor: PAULINI RALPH , POHLMAN MATTHIAS , SÖRGEL SEBASTIAN , BASTIAANS HENRICUS MARIA MARTINUS , THOMPSON SARAH , EBUENGA DOYOG CECILLE , MALVEDA UMALI ANNA , SUIZA COSARE RHOEL , PALMER CHRISTOPHER , HOKAMA TAKEO
Abstract: The invention relates to the use of a compound of formula (I) or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification.
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公开(公告)号:CA2634601C
公开(公告)日:2015-05-12
申请号:CA2634601
申请日:2006-12-13
Applicant: BASF SE
Inventor: POHLMAN MATTHIAS , HOFMANN MICHAEL , BASTIAANS HENRICUS MARIA MARTINUS , RACK MICHAEL , CULBERTSON DEBORAH L , OLOUMI-SADEGHI HASSAN , HOKAMA TAKEO , PALMER CHRISTOPHER , LANGEWALD JUERGEN
IPC: C07C323/60 , A01N37/34 , A01P5/00 , A01P7/00 , A61K31/277 , A61P33/00 , C07C255/37 , C07C317/44 , C07D235/16 , C07D261/10 , C07D271/02 , C07D277/32 , C07D317/30 , C07D333/28
Abstract: Compounds of formula I wherein X is O or S(=O)n; n is 0,1 or 2; R1 is optionally substituted alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, phenyl, hetaryl, phenylalkyl, hetaryl alkyl, optionally fused to phenyl, hetaryl or heterocyclyl; A is -NR b2, -C(=G)GR b, -C(=G)NR b2, -C(=NOR b)R b, C(=G)[N=SR b2], -C(=G)NR b-NR b2, C2-C6-alkandiyl, C2-C6-alkenediyl, C1-C3-alkyl-G-C1-C3-alkyl, wherein R b is as defined in the description, or optionally substituted phenyl, hetaryl, heterocyclyl, optionally fused to phenyl or heterocyclyl; B is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 3 carbon chain atoms; D is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 5 carbon chain atoms or C3-C6-cycloalkyl; G is oxygen or sulfur; or the enantiomers or diastereomers or salts or N-oxides thereof, processes for preparing the compounds I, pesticidal compositions and synergistic mixtures comprising compounds I, methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula I, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula I.
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公开(公告)号:ZA200806256B
公开(公告)日:2010-01-27
申请号:ZA200806256
申请日:2008-07-18
Applicant: BASF SE
Inventor: PALMER CHRISTOPHER , POHLMAN MATTHIAS , HOFMANN MICHAEL , BASTIAANS HENRICUS MARIA MARTINUS , RACK MICHAEL , CULBERTSON DEBORAH L , OLOUMI-SADEGHI HASSAN , LANGEWALD JUERGEN , HOKAMA TAKEO
IPC: A01N20100101 , C07C20100101 , C07D20100101
Abstract: Compounds of formula I wherein X is O or S(═O)n; n is 0, 1 or 2; R1 is optionally substituted alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, phenyl, hetaryl, phenylalkyl, hetaryl alkyl, optionally fused to phenyl, hetaryl or heterocyclyl; A is —NRb2, —C(=G)GRb, —C(=G)NRb2, —C(═NORb)Rb, C(=G)[N═SRb2], —C(=G)NRb—NRb2, C2-C6-alkandiyl, C2-C6-alkenediyl, C1-C3-alkyl-G-C1-C3-alkyl, wherein Rb is as defined in the description, or optionally substituted phenyl, hetaryl, heterocyclyl, optionally fused to phenyl or heterocyclyl; B is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 3 carbon chain atoms; D is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 5 carbon chain atoms or C3-C6-cycloalkyl; G is oxygen or sulfur; or the enantiomers or diastereomers or salts or N-oxides thereof, processes for preparing the compounds I, pesticidal compositions and synergistic mixtures comprising compounds I, methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula I, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula I.
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公开(公告)号:AU2006328521A1
公开(公告)日:2007-06-28
申请号:AU2006328521
申请日:2006-12-13
Applicant: BASF SE
Inventor: RACK MICHAEL , HOKAMA TAKEO , CULBERTSON DEBORAH L , LANGEWALD JURGEN , HOFMANN MICHAEL , POHLMAN MATTHIAS , BASTIAANS HENRICUS MARIA MARTI , OLOUMI-SADEGHI HASSAN , PALMER CHRISTOPHER
IPC: A01N37/34 , A01N43/40 , A01N43/52 , A01N47/02 , C07C255/37 , C07C317/10 , C07C321/20 , C07D213/67 , C07D271/06 , C07D277/32 , C07D317/32 , C07D333/28
Abstract: Compounds of formula I wherein X is O or S(═O)n; n is 0, 1 or 2; R1 is optionally substituted alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl, cycloalkyl, halocycloalkyl, cycloalkenyl, halocycloalkenyl, phenyl, hetaryl, phenylalkyl, hetaryl alkyl, optionally fused to phenyl, hetaryl or heterocyclyl; A is —NRb2, —C(=G)GRb, —C(=G)NRb2, —C(═NORb)Rb, C(=G)[N═SRb2], —C(=G)NRb—NRb2, C2-C6-alkandiyl, C2-C6-alkenediyl, C1-C3-alkyl-G-C1-C3-alkyl, wherein Rb is as defined in the description, or optionally substituted phenyl, hetaryl, heterocyclyl, optionally fused to phenyl or heterocyclyl; B is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 3 carbon chain atoms; D is an optionally substituted saturated or partially unsaturated hydrocarbon chain with 1 to 5 carbon chain atoms or C3-C6-cycloalkyl; G is oxygen or sulfur; or the enantiomers or diastereomers or salts or N-oxides thereof, processes for preparing the compounds I, pesticidal compositions and synergistic mixtures comprising compounds I, methods for the control of insects, acarids or nematodes by contacting the pests or their food supply, habitat or breeding grounds with a pesticidally effective amount of compounds formula I, and a method for treating, controlling, preventing or protecting animals against infestation or infection by parasites which comprises orally, topically or parenterally administering or applying to the animals a parasiticidally effective amount of compounds of formula I.
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公开(公告)号:CA2888390C
公开(公告)日:2021-07-20
申请号:CA2888390
申请日:2013-10-22
Applicant: BASF SE
Inventor: PAULINI RALPH , POHLMAN MATTHIAS , SORGEL SEBASTIAN , BASTIAANS HENRICUS MARIA MARTINUS , THOMPSON SARAH , EBUENGA DOYOG CECILLE , MALVEDA UMALI ANNA , SUIZA COSARE RHOEL , PALMER CHRISTOPHER , HOKAMA TAKEO
IPC: C07C255/10 , A01N37/34 , A01P7/00 , A61K31/277 , A61P33/00 , C07C255/15
Abstract: The invention relates to the use of a compound of formula (I) or a salt thereof for combating animal pests, where the symbols and indices are defined in the specification.
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公开(公告)号:ES2765405T3
公开(公告)日:2020-06-09
申请号:ES15727088
申请日:2015-04-17
Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC , BASF SE
Inventor: MENG CHARLES , MICULKA CHRISTIAN , SOLL MARK , PAULINI RALPH , POHLMAN MATTHIAS , SORGEL SEBASTIAN , BASTIAANNS HENRICUS , THOMPSON SARAH , EBUENGA DOYOG CECILLE , MALVEDA UMALI ANNA , SUIZA COSARE RHOEL , PALMER CHRISTOPHER , HOKAMA TAKEO
Abstract: Compuesto de aril alquil malononitrilo de fórmula (I), o una sal del mismo: **(Ver fórmula)** para usar en el control o prevención de una infección parasitaria de un animal con un ectoparásito seleccionado de Haematobia irritans y Stomoxys calcitrans, en el que el compuesto de fórmula (I), o sal del mismo, se administra al animal por vía tópica, y en el que Y es fenilo no sustituido o sustituido con 1, 2, 3, 4 o 5 sustituyentes R5; Q es fenilo no sustituido o sustituido con uno o más sustituyentes R6; R1 es hidrógeno, halógeno, ciano, hidroxi, alquilo C1-C6, alquenilo C2-C6, alquinilo C2-C6, cicloalquilo C3-C8, cicloalquenilo C3-C8, alcoxi C1-C6, alqueniloxi C2-C6, alquiltio C1-C6, (alcoxi C1-C6) carbonilo, en los que los átomos de carbono de los radicales alifáticos o cicloalifáticos mencionados anteriormente están no sustituidos o están sustituidos con 1, 2 o 3 sustituyentes R7; R2 es hidrógeno o halógeno; o R1 y R2 forman junto con el átomo de carbono al que están unidos, un grupo metileno o un grupo ciclopropilo; R3 es hidrógeno, halógeno, ciano, hidroxi, alquilo C1-C6, alquenilo C2-C6, alquinilo C2-C6, cicloalquilo C3-C8, cicloalquenilo C3-C8, alcoxi C1-C6, alqueniloxi C2-C6, alquiltio C1-C6, (alcoxi C1-C6) carbonilo, en los que los átomos de carbono de los radicales alifáticos o cicloalifáticos mencionados anteriormente están no sustituidos o están sustituidos con 1, 2 o 3 sustituyentes R7; R4 es hidrógeno o halógeno; o R3 y R4 forman junto con el átomo de carbono al que están unidos, un grupo metileno o un grupo ciclopropilo; cada R5, R6 es de forma independiente halógeno, ciano, azido, nitro, -SCN, SF5, alquilo C1-C6, alquenilo C2-C6, alquinilo C2-C6, en los que los átomos de carbono de los radicales alifáticos mencionados anteriormente están no sustituidos o sustituidos con uno o más Ra; cicloalquilo C3-C8 o cicloalquenilo C3-C8, en los que los átomos de carbono de los radicales cicloalifáticos mencionados anteriormente están no sustituidos o sustituidos con uno o más Rb; fenilo no sustituido o sustituido con hasta 5 Rc; un anillo heterocíclico saturado, parcialmente insaturado o aromático de 3, 4, 5, 6 o 7 miembros que contiene 1, 2 o 3 heteroátomos o grupos de heteroátomos seleccionados de N, O, S, NO, SO, SO2, en el que el anillo mencionado anteriormente está no sustituido o sustituido con hasta 5 Rd; Si(Re)3, ORf, SRf, OS(O)xRh, S(O)xRh, N(Ri)2, N(Ri)C(=O)Rm, OC(=O)Rm, C(=O)Rm, C(=O)ORf, C(=NRi)Rm, C(=S)Rm; o dos R5 en dos átomos de carbono adyacentes presentes en un anillo de fenilo son juntos un puente seleccionado de CH2CH2CH2CH2, N=CH-CH=CH, CH=N-CH=CH, N=CH-N=CH, N=CH-CH=N, OCH2CH2CH2, OCH=CHCH2, CH2OCH2CH2, OCH2CH2O, OCH2OCH2, CH2CH2CH2, CH=CHCH2, CH2CH2O, CH=CHO, CH2OCH2, CH2C(=O)O, C(=O)OCH2, O(CH2)O, SCH2CH2CH2, SCH=CHCH2, CH2SCH2CH2, SCH2CH2S, SCH2SCH2, CH2CH2S, CH=CHS, CH2SCH2, CH2C(=S)S, C(=S)SCH2, S(CH2)S, CH2CH2NRK, CH2CH=N, CH=CH-NRK, OCH=N, SCH=N y forman junto con los átomos de carbono a los que dos R5 están unidos un anillo carbocíclico o heterocíclico parcialmente insaturado o aromático de 5 o 6 miembros, en el que el anillo está no sustituido o sustituido con 1 o 2 sustituyentes seleccionados de =O, OH, CH3, OCH3, halógeno, halometilo y halometoxi; cada R7 es de forma independiente halógeno, ciano, hidroxi, alquilo C1-C6, alquenilo C2-C6, alquinilo C2-C6, cicloalquilo C3-C8, cicloalquenilo C3-C8, alcoxi C1-C6, alqueniloxi C2-C6, alquiltio C1-C6, (alcoxi C1-C6) carbonilo, OSi(Re)3, en los que los átomos de carbono de los radicales alifáticos o cicloalifáticos menciondos anteriormente están no sustituidos, parcialmente o completamente halogenados y/u oxigenados; cada Ra es de forma independiente halógeno, ciano, azido, nitro, -SCN, SF5, alquilo C1-C6, haloalquilo C1-C6, alcoxi C1-C6, haloalcoxi C1-C6, alquiltio C1-C6, alquilsulfinilo C1-C6, alquilsulfonilo C1-C6, haloalquiltio C1-C6, cicloalquilo C3- C8, halocicloalquilo C3-C8, alquenilo C2-C6, haloalquenilo C2-C6, alquinilo C2 C6, haloalquinilo C2-C6, alquil C1- C6 cicloalquilo C3-C8, ...
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