公开(公告)号：US20240376424A1

公开(公告)日：2024-11-14

申请号：US18682052

申请日：2022-09-09

Applicant: BASF SE

Inventor： Tobias MAY ,  Andrea HEROLD ,  Ingeborg HEUSCHKEL ,  Daniel Christoph HEINRICH ,  Heiko SENDROWSKI

IPC: C12N1/20 ,  A01N63/22 ,  C07K14/195 ,  C12N15/74 ,  C12P19/04 ,  C12R1/12

Abstract: Described herein are genes involved in Firmicutes exopolysaccharide production. Also described are mutations to those genes and corresponding mutated proteins to increase or stabilise exopolysaccharide production or prevent exopolysaccharide autodegradation, in particular over the course of a fermentation. Further described herein are fermentation methods and uses of the mutated genes and proteins, and of the microorganisms and the exopolysaccharides.

公开(公告)号：US20240368231A1

公开(公告)日：2024-11-07

申请号：US18682019

申请日：2022-09-09

Applicant: BASF SE

Inventor： Tobias MAY ,  Andrea HEROLD ,  Daniel Christoph HEINRICH ,  Heiko SENDROWSKI

IPC: C07K14/195 ,  C12N15/74

Abstract: Described herein are microorganisms, genes, materials and methods for improving genetic competence. In particular, described herein are individual genes/proteins and combinations thereof to improve conjugation competence in Firmicutes, and methods and uses involving such genes, proteins and respective combinations.