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1.发明申请A STORAGE-STABLE DUST-FREE HOMOGENEOUS PARTICULATE FORMULATION COMPRISING AT LEAST ONE WATER-SOLUBLE VITAMIN E-DERIVATIVE AND AT LEAST ONE HYDROPHILIC POLYMER 审中-公开一种具有至少一种水溶性维生素E衍生物和至少一种水解聚合物的储存稳定的无机均质颗粒配方
公开(公告)号：WO2014048783A1
公开(公告)日：2014-04-03
申请号：PCT/EP2013/069111
申请日：2013-09-16
Applicant: BASF SE
Inventor： GUTH, Felicitas , KOLTER, Karl , SCHÖNHERR, Michael , MÜLLER, Michael Klemens
IPC: A61K9/14 , A61K9/16 , A61K31/355
CPC classification number: A61K9/1682 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K31/355
Abstract: A storage-stable dust-free homogeneous particle formulation, consisting of: (a) at least one water-soluble Vitamin E-derivative, (b) at least one hydrophilic polymer, (c) optionally additional surface-active substances, and (d) optionally additional pharmaceutical additives, with the proviso, that the sum of (a), (b), (c) and (d) equals 100 % by weight of the formulation, and wherein the fines fraction with particle diameters of less than 100μηη is less than 10 % by weight.
Abstract translation: 一种储存稳定的无尘均质颗粒制剂，由以下组成：（a）至少一种水溶性维生素E衍生物，（b）至少一种亲水性聚合物，（c）任选地附加的表面活性物质和（d ）任选的另外的药物添加剂，条件是（a），（b），（c）和（d）的总和等于配方的100重量％，并且其中粒径小于100μe ;＆EEGR; 小于10重量％。
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公开(公告)号：WO2015124521A1
公开(公告)日：2015-08-27
申请号：PCT/EP2015/053195
申请日：2015-02-16
Applicant: BASF SE
Inventor： ERBES, Jörg , LANGE, Gerhard , KORTEKAMP, Tobias , LINNER, Bernhard , SCHNEIDER, Cecile , ULZHÖFER, Angela , HEINZ, Robert , MÜLLER, Michael Klemens
CPC classification number: C08J3/14 , B29B13/065 , C08J3/12 , C08J2381/06 , F26B3/08 , F26B5/14 , F26B2200/08
Abstract: Die vorliegende Erfindung bezieht sich auf ein Verfahren zur Trocknung von partikulären Polymeren, umfassend die Schritte: a) Vorlegen eines partikulären Polymers, das 60 Gew.-% bis 90 Gew.-% zumindest eines Lösungsmittels, bezogen auf das Gesamtgewicht von partikulärem Polymer und Lösungsmittel, enthält, b) mechanische Vortrocknung des partikulären Polymers auf 20 Gew.-% bis 50 Gew.-% des zumindest einen Lösungsmittels, bezogen auf das Gesamtgewicht von partikulärem Polymer und Lösungsmittel, wobei die mechanische Vortrocknung in Schritt b) mit einer Walzenpresse durchgeführt wird, wobei die mechanische Vortrocknung in Schritt b) mit einer Walzenpresse durchgeführt wird, und c) Endtrocknung des partikulären Polymers auf 0 Gew.-% bis 15 Gew.-% des zumindest einen Lösungsmittels, bezogen auf das Gesamtgewicht von partikulärem Polymer und Lösungsmittel, wobei das partikuläre Polymer ein Polymer ist, das Wiederholungseinheiten der Formeln (I), (II) und/oder (III) enthält. Die vorliegende Erfindung bezieht sich ferner auf ein Verfahren zur Aufarbeitung von partikulären Polymeren.
Abstract translation: 在本发明涉及一种用于干燥包括以下步骤粒状聚合物：a）提供包含.- 60重量％的粒状聚合物于90重量％的至少一种溶剂的％，基于粒状聚合物和溶剂的总重量 含有粒状聚合物，b）机械预干燥到20重量％至50重量％的至少一种溶剂的％，基于粒状聚合物和溶剂的总重量计，其中，在步骤b中的机械预干燥）是用辊压机进行 ，其中所述机械预干燥在步骤b）用辊压机进行，和c）颗粒聚合物的最终干燥至0重量％至15重量％的至少一种溶剂的％，基于粒状聚合物和溶剂的总重量计，其中 粒状聚合物是聚合物包括重复所述式（I）的单元，（II）和/或（III）含有 ， 本发明还涉及一种用于粒状聚合物的处理方法。
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3.发明申请POWDER AND GRANULE, PROCESS FOR MAKING SUCH POWDER AND GRANULE, AND USE THEREOF 审中-公开粉末和颗粒，制造这种粉末和颗粒的方法及其用途
公开(公告)号：WO2015121170A1
公开(公告)日：2015-08-20
申请号：PCT/EP2015/052533
申请日：2015-02-06
Applicant: BASF SE
Inventor： HARTMANN, Markus , REINOSO GARCIA, Marta , MÜLLER, Michael Klemens , BÖHN, Roland , BIEL, Markus Christian
CPC classification number: C11D3/3942 , C11D3/33 , C11D3/3761 , C11D11/02 , C11D17/06
Abstract: The present invention is directed towards a process for making a powder or granule containing (A) at least one chelating agent selected from methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS) and their respective alkali metal salts, (B) at least one homo- or copolymer of (meth)acrylic acid, partially or fully neutralized with alkali, said process comprising the steps of (a) mixing the at least one chelating agent (A) and the at least one homo- or copolymer (B) in the presence of water, (b) removing most of said water by spray-drying or spray granulation using a gas with an inlet temperature of at least 125°C.
Abstract translation: 本发明涉及制备含有（A）至少一种选自甲基甘氨酸二乙酸（MGDA）和谷氨酸二乙酸酯（GLDA）和亚氨基二琥珀酸（IDS）及其各自的碱金属的螯合剂的粉末或颗粒的方法 盐，（B）至少一种与碱部分或完全中和的（甲基）丙烯酸的均聚物或共聚物，所述方法包括以下步骤：（a）将至少一种螯合剂（A）和至少一种螯合剂 均聚物或共聚物（B），（b）使用入口温度至少为125℃的气体通过喷雾干燥或喷雾造粒除去大部分所述水。
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4.发明公开POWDER AND GRANULE, PROCESS FOR MAKING SUCH POWDER AND GRANULE, AND USE THEREOF 审中-公开粉末和颗粒，用于制备这种粉末及其用途GRANULATS AND
公开(公告)号：EP3105309A1
公开(公告)日：2016-12-21
申请号：EP15702810.1
申请日：2015-02-06
Applicant: BASF SE
Inventor： HARTMANN, Markus , REINOSO GARCIA, Marta , MÜLLER, Michael Klemens , BÖHN, Roland , BIEL, Markus Christian
CPC classification number: C11D3/3942 , C11D3/33 , C11D3/3761 , C11D11/02 , C11D17/06
Abstract: The present invention is directed towards a process for making a powder or granule containing (A) at least one chelating agent selected from methyl glycine diacetic acid (MGDA) and glutamic acid diacetate (GLDA) and iminodisuccinic acid (IDS) and their respective alkali metal salts, (B) at least one homo- or copolymer of (meth)acrylic acid, partially or fully neutralized with alkali, said process comprising the steps of (a) mixing the at least one chelating agent (A) and the at least one homo- or copolymer (B) in the presence of water, (b) removing most of said water by spray-drying or spray granulation using a gas with an inlet temperature of at least 125° C.
Abstract translation: 本发明涉及一种用于制备粉末或颗粒含有（A）从甲基甘氨酸二乙酸（MGDA）和谷氨酸二乙酸（GLDA）和亚氨基二琥珀酸（IDS）中选出的至少一种螯合剂及其respectivement碱金属 盐，（B）至少一种均聚物或（甲基）丙烯酸的共聚物，部分或完全用碱中，所述方法包括（a）将所述至少一种螯合剂（A）和该至少一个的步骤 均聚物或在水的存在下的共聚物（b），（b）通过喷雾干燥除去大部分所述水的或在至少125℃的入口温度使用气体与喷雾造粒
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Patent Agency Ranking
公开(公告)号：EP3107953B1
公开(公告)日：2018-04-11
申请号：EP15706192.0
申请日：2015-02-16
Applicant: BASF SE
Inventor： ERBES, Jörg , LANGE, Gerhard , KORTEKAMP, Tobias , LINNER, Bernhard , SCHNEIDER, Cecile , ULZHÖFER, Angela , HEINZ, Robert , MÜLLER, Michael Klemens
CPC classification number: C08J3/14 , B29B13/065 , C08J3/12 , C08J2381/06 , F26B3/08 , F26B5/14 , F26B2200/08
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公开(公告)号：EP3107953A1
公开(公告)日：2016-12-28
申请号：EP15706192.0
申请日：2015-02-16
Applicant: BASF SE
Inventor： ERBES, Jörg , LANGE, Gerhard , KORTEKAMP, Tobias , LINNER, Bernhard , SCHNEIDER, Cecile , ULZHÖFER, Angela , HEINZ, Robert , MÜLLER, Michael Klemens
CPC classification number: C08J3/14 , B29B13/065 , C08J3/12 , C08J2381/06 , F26B3/08 , F26B5/14 , F26B2200/08
Abstract: The invention relates to a method for drying particulate polymers, having the following steps: a) providing a particulate polymer which contains 60 wt.% to 90 wt.% of at least one solvent, based on the total weight of the particulate polymer and the solvent, b) mechanically pre-drying the particulate polymer to 20 wt.% to 50 wt.% of the at least one solvent, based on the total weight of the particulate polymer and the solvent, wherein the mechanical pre-drying in step b) is carried out using a rolling press, and c) final drying the particulate polymer to 0 wt.% to 15 wt. of the at least one solvent, based on the total weight of the particulate polymer and the solvent. The particular polymer is a polymer which contains the repeating units of the formulas (I), (II) and/or (II). The invention further relates to a method for processing particulate polymers.
Abstract translation: 本发明还涉及一种用于后处理的粒状聚合物。
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公开(公告)号：EP3105309B1
公开(公告)日：2019-04-10
申请号：EP15702810.1
申请日：2015-02-06
Applicant: BASF SE
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8.发明授权A STORAGE-STABLE DUST-FREE HOMOGENEOUS PARTICULATE FORMULATION COMPRISING AT LEAST ONE WATER-SOLUBLE VITAMIN E-DERIVATIVE AND AT LEAST ONE HYDROPHILIC POLYMER 有权贮存稳定，无灰尘，均一的颗粒与至少一种水溶性维生素E衍生物和至少一种亲水性聚合物配方
公开(公告)号：EP2911651B1
公开(公告)日：2016-06-22
申请号：EP13762138.9
申请日：2013-09-16
Applicant: BASF SE
Inventor： GUTH, Felicitas , KOLTER, Karl , SCHÖNHERR, Michael , MÜLLER, Michael Klemens
IPC: A61K9/14 , A61K9/16 , A61K31/355
CPC classification number: A61K9/1682 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K31/355
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9.发明公开A STORAGE-STABLE DUST-FREE HOMOGENEOUS PARTICULATE FORMULATION COMPRISING AT LEAST ONE WATER-SOLUBLE VITAMIN E-DERIVATIVE AND AT LEAST ONE HYDROPHILIC POLYMER 有权贮存稳定，无灰尘，均一的颗粒与至少一种水溶性维生素E衍生物和至少一种亲水性聚合物配方
公开(公告)号：EP2911651A1
公开(公告)日：2015-09-02
申请号：EP13762138.9
申请日：2013-09-16
Applicant: BASF SE
Inventor： GUTH, Felicitas , KOLTER, Karl , SCHÖNHERR, Michael , MÜLLER, Michael Klemens
IPC: A61K9/14 , A61K9/16 , A61K31/355
CPC classification number: A61K9/1682 , A61K9/1635 , A61K9/1641 , A61K9/1652 , A61K31/355
Abstract: A storage-stable dust-free homogeneous particle formulation, consisting of: (a) at least one water-soluble Vitamin E-derivative, (b) at least one hydrophilic polymer, (c) optionally additional surface-active substances, and (d) optionally additional pharmaceutical additives, with the proviso, that the sum of (a), (b), (c) and (d) equals 100 % by weight of the formulation, and wherein the fines fraction with particle diameters of less than 100μηη is less than 10 % by weight.
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