公开(公告)号：WO2016180664A1

公开(公告)日：2016-11-17

申请号：PCT/EP2016/059821

申请日：2016-05-03

Applicant: BASF SE

Inventor： STAMM, Armin ,  SCHMIDT, Thomas ,  ORR, Christopher ,  MANNING, Jeremy

IPC: C07C227/18 ,  C07C229/24 ,  C09K8/035 ,  C11D3/33

CPC classification number: C07C227/18 ,  C01D1/04 ,  C07C229/16 ,  C09K8/035 ,  C11D3/33 ,  C11D11/0023

Abstract: Process for making a chelating agent according to the general formula (I), R 1 -CH(COOX 1 )-N(CH2COOX 1 ) 2 wherein R 1 is selected from hydrogen, C 1 -C 4 -alkyl, phenyl, benzyl, CH 2 OH, and CH 2 CH 2 COOX 1 , X 1 is (Μ χ Η 1-χ ), M being selected from alkali metal, x is in the range of from 0.6 to 1, said process comprising the following steps: (a) providing a solid, a slurry or a solution of a compound according to general formula (II a) R 1 -CH(COOX 2 )-N(CH 2 CN) 2 wherein X 2 is (M y H 1-y ), M being selected from alkali metal, y is in the range of from zero to 1, (b) contacting said solid or slurry or solution with an aqueous solution of alkali metal hydroxide, wherein the molar ratio of alkali metal ions to nitrile groups is in the range of from 0.6:1 to 0.95:1, (c) reacting said compound according to general formula (II a) with said alkali metal hydroxide.

Abstract translation: 制备根据通式（I）的螯合剂的方法，R1-CH（COOX1）-N（CH2COOX1）2，其中R1选自氢，C1-C4-烷基，苯基，苄基，CH2OH和CH2CH2COOX1，X1 是（ΜχH1-χ），M选自碱金属，x在0.6至1的范围内，所述方法包括以下步骤：（a）提供一般化合物的固体，浆液或溶液 式（IIa）R1-CH（COOX2）-N（CH2CN）2，其中X2是（MyH1-y），M选自碱金属，y在0至1的范围内，（b）使所述固体 或碱性金属氢氧化物水溶液的浆液或溶液，其中碱金属离子与腈基的摩尔比在0.6:1至0.95:1的范围内，（c）使通式（II）的所述化合物 a）与所述碱金属氢氧化物反应。

公开(公告)号：EP3294702B1

公开(公告)日：2020-12-02

申请号：EP16720815.6

申请日：2016-05-03

Applicant: BASF SE

Inventor： STAMM, Armin ,  SCHMIDT, Thomas ,  ORR, Christopher ,  MANNING, Jeremy

IPC: C07C227/18 ,  C07C229/24 ,  C09K8/035 ,  C11D3/33