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公开(公告)号：AU2006328585B2
公开(公告)日：2012-05-03
申请号：AU2006328585
申请日：2006-12-11
Applicant: BASF SE
Inventor： KOLTER KARL , WICHTNER MARCUS , SCHONHERR MICHAEL , MITTWOLLEN JAN-PETER
Abstract: The invention relates to a pharmaceutical formulation in the form of agglomerates containing a) 60 - 97 % by weight of sugar or sugar alcohols, b) 1 - 25 % by weight of cross-linked polyvinylpyrrolidone, c) 1 - 15 % by weight of water-insoluble, film-forming polymers, d) 0 - 15 % by weight of water-soluble polymers, and e) 0 - 15 % by weight of other pharmaceutically suitable adjuvants, the sum of components a) to e) adding up to 100 % by weight.
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公开(公告)号：ZA201109262B
公开(公告)日：2013-02-27
申请号：ZA201109262
申请日：2011-12-15
Applicant: BASF SE
Inventor： MRZENA FRANK , SCHONHERR MICHAEL , HEINZ ROBERT , HEIDEN-FELDER THOMAS
IPC: B01J20060101 , C07C20060101 , C11D20060101
Abstract: A process for the preparation of a spray-dried powder containing at least one glycine-N,N-diacetic acid compound of a formula MOOC—CHR—N(CH2COOM)2, where R is a C1-12-alkyl and M is an alkali metal, the process including: preparing an aqueous solution containing the glycine-N,N-diacetic acid compound; concurrently passing the aqueous solution and air into a spray-drying apparatus; atomizing the aqueous solution by feeding the aqueous solution onto a rotating disk or by compressing the aqueous solution with a pump to a pressure of ≧20 bar absolute, to obtain fine liquid droplets; and drying the droplets, to obtain the spray-dried powder, where a temperature gradient between the aqueous solution and the air is in a range from 70 to 350° C., and a content of the glycine-N,N-diacetic acid compound in the aqueous solution is ≧84% by weight, based on a total weight of the dry mass.
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Patent Agency Ranking
公开(公告)号：AU2008258627A1
公开(公告)日：2008-12-11
申请号：AU2008258627
申请日：2008-06-03
Applicant: BASF SE
Inventor： SCHONHERR MICHAEL , MEYER-BOHM KATHRIN , KOLTER KARL , MASCHKE ANGELIKA , GEBERT SILKE
Abstract: Pharmaceutical formulation in the form of agglomerates comprising A) an excipient content composed of a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of a disintegrant, c) 1-15% by weight of water-insoluble, film-forming polymers d) 0-15% by weight of water-soluble polymers and e) 0-15% by weight of further pharmaceutically customary excipients the total of the components a) to e) being 100% by weight, and B) at least one active ingredient.
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公开(公告)号：AU2010305833A1
公开(公告)日：2012-04-19
申请号：AU2010305833
申请日：2010-10-11
Applicant: BASF SE
Inventor： MRZENA FRANK , MENGE ULRICH , SCHONHERR MICHAEL , HEIDENFELDER THOMAS
IPC: B01J2/04 , C07C227/42 , C11D3/33 , C11D11/00
Abstract: The invention relates to a method for producing a powder containing one or more complexing agent salts of the general formula (I), starting from an aqueous solution, containing the one or more complexing agent salts at a concentration of 10 to 80% by weight, in relation to the total weight of the aqueous solution, in a spray drying process, comprising an atomizing step and a drying step, characterized in that the atomizing step is performed adding fine crystalline dust of the same complexing agent salt or salts that are found in the aqueous solution, or one or more complexing agent salts differing therefrom, having an upper limit for the average particle diameter of the fine crystalline dust that is less than the lower limit of the average particle diameter of the powder obtained according to the method by at least a factor of 2, at a proportion of 0.1 to 20% by weight, in relation to the weight of the powder obtained according to the method.
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5.发明专利
公开(公告)号：BR112013006404A2
公开(公告)日：2016-07-05
申请号：BR112013006404
申请日：2011-09-21
Applicant: BASF SE
Inventor： BECKER FRANCOIS , WEBER FRANZ , SCHONHERR MICHAEL , BLEI STEFAN
Abstract: processo para produzir grânulos, formulação, e, usos dos grânulos e dos aglomerados prensados. o que é proposto é um processo para produzir grânulos, compreendendo um ou mais sais de agentes de complexação da fórmula geral (i) formula de uma solução de partida aquosa que compreende o um ou mais sais de agente de complexação em uma concentração de 10 a 80% em peso, com base no peso total da solução de partida aquosa, em um aparelho de feixes.
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公开(公告)号：ZA201203359B
公开(公告)日：2013-07-31
申请号：ZA201203359
申请日：2012-05-09
Applicant: BASF SE
Inventor： MRZENA FRANK , MENGE ULRICH , SCHONHERR MICHAEL , HEIDENFELDER THOMAS
IPC: B01J20060101 , C07C20060101 , C11D20060101
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公开(公告)号：AU2006328585A1
公开(公告)日：2007-06-28
申请号：AU2006328585
申请日：2006-12-11
Applicant: BASF SE
Inventor： KOLTER KARL , WICHTNER MARCUS , SCHONHERR MICHAEL , MITTWOLLEN JAN-PETER
Abstract: A pharmaceutical formulation in the form of agglomerates comprising a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of crosslinked polyvinylpyrrolidone, c) 1-15% by weight of water-insoluble, film-forming polymers, d) 0-15% by weight of water-soluble polymers and e) 0-15% by weight of further pharmaceutically customary excipients, the sum of the components a) to e) being 100% by weight.
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