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    METHOD FOR THE PRODUCTION OF A POLYMERIZED PRODUCT
    2.
    发明申请
    METHOD FOR THE PRODUCTION OF A POLYMERIZED PRODUCT 审中-公开
    生产聚合物的方法

    公开(公告)号：WO2012171983A3

    公开(公告)日：2013-05-10

    申请号：PCT/EP2012061253

    申请日：2012-06-14

    Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA ,  DELMOTTE YVES

    Inventor： DELMOTTE YVES

    IPC: C08L5/04 ,  A61K38/36 ,  B01F13/00 ,  C07K14/75 ,  C07K14/78 ,  C08L5/08 ,  C08L89/00 ,  C08L89/06

    CPC classification number: C12P21/00 ,  B01F13/0071 ,  C07K1/02 ,  C07K14/75 ,  C07K14/765 ,  C07K14/78 ,  C08L5/04 ,  C08L5/08 ,  C08L89/00 ,  C08L89/06 ,  C12N9/54

    Abstract: The invention discloses a method for the production of a polymerized product comprising the following steps: - providing a polymerization device to which a polymerization mixture and a separation medium can be applied and wherein flow of said mixture and medium can be conducted in appropriate ducts for said mixture and medium, - transporting said polymerization mixture in a duct of said polymerization device thereby allowing the polymerization reaction, - transporting said mixture in a duct of said polymerization device in a continuous flow, - interrupting said continuous flow of said mixture with said separation medium so as to obtain consecutive volumes of said mixture and volumes of said separation medium, - further transporting said consecutive volumes of said mixture and volumes of said separation medium in a duct of said polymerization device wherein said mixture further polymerizes to obtain a discontinuous polymerized product, and removing said discontinuous polymerized product from said polymerization device.

    Abstract translation: 本发明公开了一种生产聚合产物的方法，包括以下步骤： - 提供聚合装置，聚合混合物和分离介质可以被施加到聚合装置上，并且所述混合物和介质的流动可以在适当的管道中进行，用于所述 混合物和介质， - 将所述聚合混合物输送在所述聚合装置的管道中，从而允许聚合反应，以连续流动方式在所述聚合装置的管道中输送所述混合物， - 用所述分离介质中断所述混合物的所述连续流动 以便获得所述分离介质的所述混合物和体积的连续体积， - 在所述聚合装置的管道中进一步输送所述连续体积的所述分离介质的所述混合物和体积，其中所述混合物进一步聚合以获得不连续的聚合产物， 并除去所述不连续聚合产物 从所述聚合装置。

    FIBRIN POROUS STRUCTURE
    4.
    发明申请
    FIBRIN POROUS STRUCTURE 审中-公开
    纤维多孔结构

    公开(公告)号：WO0185225A2

    公开(公告)日：2001-11-15

    申请号：PCT/US0115073

    申请日：2001-05-09

    Applicant: BAXTER INT

    Inventor： DELMOTTE YVES

    IPC: A61B17/00 ,  A61F2/00 ,  A61L15/32 ,  A61L27/22 ,  A61L27/44 ,  A61L27/56 ,  A61L31/04 ,  B05B11/00 ,  B05B11/02

    CPC classification number: A61L27/56 ,  A61B17/00491 ,  A61B2017/00495 ,  A61F2310/00377 ,  A61L15/32 ,  A61L27/225 ,  A61L27/44 ,  A61L31/046 ,  B05B11/0078 ,  B05B11/02 ,  C08L89/00

    Abstract: The present invention provides a porous structure of fibrin or fibrinogen material. The structure in its substantially dry form, having a compression strain of less than 8 %, and a creep modulus higher than 1.5 x 10 Pa. The compression strain and creep modulus being measured for a sample having a diameter of 5 mm on which a compression of 2500 milli Newtons is exerted with a compression ramp of 500 milli Newtons per minute, after a compression release step following an initial compression of 2500 milli Newtons with a compression ramp of 500 milli Newtons per minute. After hydration, the structure has a porosity wherein at least 50 % by volume of the total porosity is formed by channels with an open cross section of more than 500 mu m .

    Abstract translation: 本发明提供纤维蛋白或纤维蛋白原材料的多孔结构。 其基本干燥形式的结构，压缩应变小于8％，蠕变模量高于1.5×10 6 Pa。对于直径为5mm的样品测量的压缩应变和蠕变模量 在500毫牛顿/分钟的压缩斜坡初始压缩2500毫牛顿之后的压​​缩释放步骤之后，以2500毫牛顿/分钟的压缩斜率施加2500毫牛顿的压缩。 在水合后，该结构具有孔隙率，其中总孔隙率的至少50体积％通过具有大于500μm2的开放横截面的通道形成。

    Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions
    9.
    发明专利
    Self-supporting sheet-like material of cross-linked fibrin for preventing post operative adhesions 未知

    公开(公告)号：AU697045B2

    公开(公告)日：1998-09-24

    申请号：AU4536296

    申请日：1996-01-16

    Applicant: BAXTER INT

    Inventor： DELMOTTE YVES ,  KRACK GENEVIEVE

    IPC: A61L15/64 ,  A61F2/00 ,  A61L15/32 ,  A61L27/00 ,  A61L27/22 ,  A61L31/00 ,  A61L31/04 ,  A61P43/00 ,  C08J5/18

    Abstract: This invention provides a medical device for delivering volumetric quantities of a first and a second biochemically reactive fluid comprising a first container having an opening, the first container being adapted to contain the first biochemically reactive fluid; a second container having a second fluid opening adjacent the first fluid opening, the second container being adapted to contain the second biochemically reactive fluid; a spray unit for separately atomizing the first and second biochemically reactive fluids into an aerosol with at least one energy source of a liquid energy, a mechanical energy, a vibration energy, and an electric energy; a fluid pressurizer for pressurizing the first and the second biochemically reactive fluids for delivery under pressure through the spray unit onto a surface; and wherein the first and second biochemically reactive fluids first mix on the surface.

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