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公开(公告)号:WO2007016611A3
公开(公告)日:2007-05-10
申请号:PCT/US2006030051
申请日:2006-08-02
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor: TROUILLY JEAN LUC , DESBROSSES FREDDY , BONNOT DENIS , MELIN CHRISTIAN
CPC classification number: A61J1/2093 , A23L33/10 , A23L33/115 , A23L33/16 , A23L33/17 , A23L33/40 , A61J1/10 , A61J1/1462 , A61J1/2024 , A61K9/0019 , A61K31/198 , A61K33/00 , A61K36/48 , A61K36/63 , A61K45/06 , B32B27/08 , G01N21/783 , G01N31/225 , A61K2300/00
Abstract: An oxygen indicator is provided for revealing the presence of oxygen in a container housing a medical formulation. The indicator can be formulated with components deemed safe for use with medical products. A preferred oxygen indicator can withstand heat sterilization and prolonged storage and can provide a distinct and marked color change to indicate oxygen is present. Preferably, the indicator can be manufactured in its oxidized form and reduced upon steam sterilization. Additionally, both the color of the reduced form and the color of the oxidized form should not fade or significantly change during storage. Moreover, once a color change has occurred indicating the presence of oxygen, the oxidized color preferably remains substantially unchanged visually to the observer even after prolonged storage. The oxygen indicator can be housed in a polymeric pouch or packet having a transparent portion for viewing the color of the indicator.
Abstract translation: 提供氧气指示器用于揭示在容纳医疗制剂的容器中存在氧气。 该指示剂可以配制成被认为安全用于医疗产品的部件。 优选的氧气指示器可以承受热灭菌和延长的储存,并且可以提供明显的和显着的颜色变化以指示存在氧气。 优选地,指示剂可以以其氧化形式制造并且在蒸汽灭菌时减少。 此外,还原形式的颜色和氧化形式的颜色都不应在储存期间褪色或显着变化。 此外,一旦出现指示存在氧气的颜色变化,即使在长时间储存之后,氧化的颜色也优选保持与观察者的视觉上基本上不变。 氧指示剂可以容纳在具有用于观察指示剂的颜色的透明部分的聚合物袋或包装中。
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公开(公告)号:CA2617627C
公开(公告)日:2015-02-24
申请号:CA2617627
申请日:2006-08-02
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor: TROUILLY JEAN LUC , DESBROSSES FREDDY , BONNOT DENIS , MELIN CHRISTIAN
Abstract: An oxygen indicator is provided for revealing the presence of oxygen in a container housing a medical formulation. The indicator can be formulated with components deemed safe for use with medical products. A preferred oxygen indicator can withstand heat sterilization and prolonged storage and can provide a distinct and marked color change to indicate oxygen is present. Preferably, the indicator can be manufactured in its oxidized form and reduced upon steam sterilization. Additionally, both the color of the reduced form and the color of the oxidized form should not fade or significantly change during storage. Moreover, once a color change has occurred indicating the presence of oxygen, the oxidized color preferably remains substantially unchanged visually to the observer even after prolonged storage. The oxygen indicator can be housed in a polymeric pouch or packet having a transparent portion for viewing the color of the indicator.
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公开(公告)号:ES2525930T3
公开(公告)日:2015-01-02
申请号:ES06789170
申请日:2006-08-02
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor: TROUILLY JEAN LUC , DESBROSSES FREDDY , BONNOT DENIS , MELIN CHRISTIAN
Abstract: Un indicador de oxígeno para detectar la presencia de oxígeno en un recipiente médico, comprendiendo el indicador de oxígeno: a) más de 6 y menos de 60 g/l de índigo carmín; b) un tampón para ajustar el pH a un intervalo de 9,0 a 9,75; c) de 150 g/l a 210 g/l de celulosa microcristalina; d) un agente reductor; y e) agua, en el que el color de la forma oxidada del indicador de oxígeno es distinto del color de la forma reducida del indicador de oxígeno y en el que, después de la esterilización en autoclave, el color de la forma reducida sigue siendo distinto del color de la forma oxidada y el color de la forma oxidada sigue siendo distinto del color de la forma reducida durante al menos seis meses a 40°C.
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公开(公告)号:CA2616928A1
公开(公告)日:2007-04-05
申请号:CA2616928
申请日:2006-08-02
Applicant: BAXTER INT , BAXTER HEALTHCARE SA
Inventor: DESBROSSES FREDDY , TROUILLY JEAN-LUC , MELIN CHRISTIAN , BONNOT DENIS
Abstract: A multiple chamber container for separately storing components of a parenteral nutritional formulation is provided. The multiple chamber container may include frangible barriers, preferably peelable seals separating the chambers from each other. The container preferably facilitates the selective activation of the peelable seals to permit the admixing of less than all the separately stored components. The container may include a chamber positioned at each of the opposite lateral ends of the container and at least one additional chamber between the lateral chambers. The at least one additional chamber may have a longitudinal length substantially less than the longitudinal length of at least one of the lateral chambers. This configuration allows for selective opening of the seals since when rolling the container from the top avoids pressurizing the at least one additional chamber and inadvertent activation of a seal. The longitudinal length of the at least one additional chamber may be from about two-thirds to about three-fourths the longitudinal length of at least one of the lateral chambers. Alternatively, the container may include a hanger flap extending from a top end of the container towards the bottom end a substantially greater distance relative to the at least one additional chamber than the lateral chambers.
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公开(公告)号:CA2617230A1
公开(公告)日:2007-02-08
申请号:CA2617230
申请日:2006-08-02
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor: BONNOT DENIS , MELIN CHRISTIAN , DESBROSSES FREDDY , TROUILLY JEAN LUC
IPC: A61J1/00
Abstract: A medical product and parenteral formulation are provided. The parenteral formulation is preferably for fluid restricted patients such as pediatric patients and can include amino acids, lipids, carbohydrates and electrolytes . The parenteral formulation can be housed in a multi-chamber container for separately storing a amino acid component, a lipid component and a carbohydrate component to provide a medical product. Frangible barriers preferably peelable seals separate the components and allow for admix to for m a just prior to administration. Electrolytes can also be included in one or both of the carbohydrate and amino acid components; preferably the electrolytes are included in the amino acid component and the amino acid component includes cysteine. The multi-chamber container preferably facilitates the selective activation of the peelable seals to permit the admixing of less than all the separately stored components. The medical product can include a parenteral formulation for supplying the mean nutritional requirements for separate patient populations, such as for prete rm infants, term to two year olds, and two to eighteen year olds.
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公开(公告)号:PL327014A1
公开(公告)日:1998-11-09
申请号:PL32701497
申请日:1997-09-09
Applicant: BAXTER INT
Inventor: BECKER MICHAEL , MASTERSON MICHAEL , DESBROSSES FREDDY
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公开(公告)号:AU2006295338A1
公开(公告)日:2007-04-05
申请号:AU2006295338
申请日:2006-08-02
Applicant: BAXTER HEALTHCARE SA , BAXTER INT
Inventor: DESBROSSES FREDDY , TROUILLY JEAN-LUC , BONNOT DENIS , MELIN CHRISTIAN
Abstract: A multiple chamber container for separately storing components of a parenteral nutritional formulation is provided. The multiple chamber container may include frangible barriers, preferably peelable seals separating the chambers from each other. The container preferably facilitates the selective activation of the peelable seals to permit the admixing of less than all the separately stored components. The container may include a chamber positioned at each of the opposite lateral ends of the container and at least one additional chamber between the lateral chambers. The at least one additional chamber may have a longitudinal length substantially less than the longitudinal length of at least one of the lateral chambers. This configuration allows for selective opening of the seals since when rolling the container from the top avoids pressurizing the at least one additional chamber and inadvertent activation of a seal. The longitudinal length of the at least one additional chamber may be from about two-thirds to about three-fourths the longitudinal length of at least one of the lateral chambers. Alternatively, the container may include a hanger flap extending from a top end of the container towards the bottom end a substantially greater distance relative to the at least one additional chamber than the lateral chambers.
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公开(公告)号:DE69729280T2
公开(公告)日:2005-06-02
申请号:DE69729280
申请日:1997-09-09
Applicant: BAXTER INT
Inventor: BECKER MICHAEL , MASTERSON MICHAEL , DESBROSSES FREDDY
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公开(公告)号:DK0883396T3
公开(公告)日:2004-06-28
申请号:DK97941488
申请日:1997-09-09
Applicant: BAXTER INT
Inventor: BECKER MICHAEL , MASTERSON MICHAEL , DESBROSSES FREDDY
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公开(公告)号:AT267573T
公开(公告)日:2004-06-15
申请号:AT97941488
申请日:1997-09-09
Applicant: BAXTER INT
Inventor: BECKER MICHAEL , MASTERSON MICHAEL , DESBROSSES FREDDY
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