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公开(公告)号：DK0561141T3
公开(公告)日：2002-10-14
申请号：DK93101786
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A23L1/305 , A61K31/475 , A61K31/195 , A61P3/00
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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公开(公告)号：DE69232409D1
公开(公告)日：2002-03-21
申请号：DE69232409
申请日：1992-11-12
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , TITUS ALLAN EDWARD , JENKE DENNIS
Abstract: A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.
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公开(公告)号：AU3371593A
公开(公告)日：1993-09-23
申请号：AU3371593
申请日：1993-02-18
Applicant: BAXTER INT
Inventor： LUDWIG JOSEF KARL , JOHNSON DOUGLAS GILES
IPC: A61K31/195 , A23L1/305 , A61K31/475 , A61P3/00
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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公开(公告)号：ES2178639T5
公开(公告)日：2005-09-01
申请号：ES93101786
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A23L1/305 , A61K31/475 , A61P3/00 , A61K31/195 , A61K31/198 , A61K31/401 , A61K31/405
Abstract: LA INVENCION SUMINISTRA UNA SOLUCION DE AMINOACIDO ALTAMENTE CONCENTRADA, NUTRICIONALMENTE UTIL. EN UNA CONFORMACION, LA FORMULACION TIENE UN AMPLIO PERFIL DE AMINOACIDOS QUE ES ALTO TANTO EN AMINOACIDOS DE CADENA RAMIFICADA COMO ALTO EN EL PORCENTAJE TOTAL DE AMINOACIDOS. ADICIONALMENTE, LA INVENCION SUMINISTRA UN METODO PARA SELECCIONAR EL PERFIL DE AMINOACIDOS PARA OBTENER UNA CONCENTRACION MAXIMA DE AMINOACIDOS. PARA ESTE EXTREMO, SE SUMINISTRA UNA SOLUCION ESTABLE DE AMINOACIDOS QUE TIENE UN EQUILIBRIO NUTRICIONALMENTE APROPIADO DE AMINOACIDOS QUE COMPRENDE UNA CONCENTRACION TOTAL DE AMINOACIDOS IGUAL O MAYOR AL 18%. EN UNA CONFORMACION, SE SUMINISTRA UNA SOLUCION DE AMINOACIDOS QUE COMPRENDE APROXIMADAMENTE ENTRE UN 18 Y UN 22% DE AMINOACIDOS DE CADENA RAMIFICADA; Y UNA CONCENTRACION TOTAL DE AMINOACIDOS IGUAL O MAYOR AL 18%.
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公开(公告)号：ES2178639T3
公开(公告)日：2003-01-01
申请号：ES93101786
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A23L1/305 , A61K31/195 , A61K31/475 , A61P3/00
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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Patent Agency Ranking
公开(公告)号：DE69232409T2
公开(公告)日：2002-11-07
申请号：DE69232409
申请日：1992-11-12
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , TITUS ALLAN EDWARD , JENKE DENNIS
Abstract: A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.
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公开(公告)号：AU654421B2
公开(公告)日：1994-11-03
申请号：AU3075192
申请日：1992-11-12
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , JENKE DENNIS R , TITUS ALLAN EDWARD
Abstract: A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.
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公开(公告)号：DK0561141T4
公开(公告)日：2005-04-18
申请号：DK93101786
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A23L1/305 , A61K31/475 , A61P3/00 , A61K31/195 , A61K31/198 , A61K31/401 , A61K31/405
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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公开(公告)号：PT561141E
公开(公告)日：2002-11-29
申请号：PT93101786
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A23L1/305 , A61K31/475 , A61K31/195 , A61P3/00
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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公开(公告)号：DE69332039D1
公开(公告)日：2002-07-25
申请号：DE69332039
申请日：1993-02-05
Applicant: BAXTER INT
Inventor： JOHNSON DOUGLAS GILES , LUDWIG JOSEF KARL
IPC: A61K31/195 , A23L1/305 , A61K31/475 , A61P3/00
Abstract: The present invention provides a nutritionally useful highly concentrated amino acid solution. In an embodiment, the formulation has a broad amino acid profile that is both high in branched chain amino acids and high in overall percent of amino acids. Additionally, the present invention provides a method of selecting the amino acid profile so as to obtain a maximum amino acid concentration. To this end, a stable amino acid solution having a nutritionally appropriate balance of amino acids comprising a total amino acid concentration equal to or greater than 18% (wt/vol) is provided. In an embodiment, an amino acid solution is provided comprising approximately 18 to about 22% branched chain amino acids (wt/wt); and a total amino acid concentration equal to or greater than 18% (wt/vol).
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