公开(公告)号：WO2004037156A3

公开(公告)日：2005-04-28

申请号：PCT/US0334051

申请日：2003-10-24

Applicant: BAXTER INT

Inventor： MATHIAS JEAN-MARIE ,  RONDEAU GEORGES ,  PETERSON GRANT A ,  BOMBINO ARMANDO ,  JOIE MICHEL

IPC: A61B5/00 ,  A61B5/15 ,  A61B5/155 ,  A61J20060101 ,  A61M1/02 ,  A61M1/36

CPC classification number: A61M1/0236 ,  A61B5/15003 ,  A61B5/150282 ,  A61B5/150305 ,  A61B5/150366 ,  A61B5/150396 ,  A61B5/150511 ,  A61B5/150572 ,  A61B5/150755 ,  A61B5/150992 ,  A61B5/154 ,  A61B5/155 ,  A61M1/0209 ,  A61M1/3693

Abstract: A sampling apparatus is disclosed that includes a sample container and a sample device receiver in communication with tubing connected to the container. The receiver being adapted to receive a sampling device for withdrawing a fluid sample from the tubing and may be directly attached to a connector located between segments of the tubing.

Abstract translation: 公开了一种采样设备，其包括与连接到容器的管道连通的样品容器和样品装置接收器。 接收器适于接收采样装置以从管道中抽出流体样品，并且可以直接连接到位于管道段之间的连接器。

公开(公告)号：EP1469904A4

公开(公告)日：2005-05-11

申请号：EP03703927

申请日：2003-01-21

Applicant: BAXTER INT

Inventor： MATHIAS JEAN-MARIE ,  DI STEFANI GIANNI

IPC: A61B19/00 ,  A61M39/28 ,  F16K7/06

CPC classification number: A61M39/284 ,  A61J1/10 ,  A61M39/08 ,  A61M2202/0413 ,  F16K7/063

Abstract: A method for controlling the flow of liquid through a flexible tube in a blood collection set is provided. The set includes a venipuncture needle (12), a tube (14) for receiving blood and which provides branches to a blood collection container (18) and to a sampling pouch (20), a first flow control clamp (22) and an irreversibly closable flow control clamp (30) on the two branches. The method allows blood to flow from the tube (14) to the sampling pouch (20), irreversibly closing the flow control clamp (30) on the branch to the sampling pouch (20) whereby that flow-path is irreversibly closed and thereafter allowing blood to flow from the tube (14) to the collection (18) container via the other branch. The irreversibly closable flow control clamp (30) includes a flexible body (34) apertures (40, 44) and having two legs (36, 38) moveable between a spaced apart and a closed position, a tube contacting member (48) for clamping a tube passing through the apertures when the legs are in the closed position.

公开(公告)号：WO2006039251A3

公开(公告)日：2006-08-03

申请号：PCT/US2005034504

申请日：2005-09-27

Applicant: BAXTER INT ,  MATHIAS JEAN-MARIE ,  BLICKHAN BRYAN J ,  HALDIMAN STEPHANIE ,  SERVI LAWRENCE J JR ,  BERNES JEAN-CLAUDE ,  BISCHOF DANIEL F

Inventor： MATHIAS JEAN-MARIE ,  BLICKHAN BRYAN J ,  HALDIMAN STEPHANIE ,  SERVI LAWRENCE J JR ,  BERNES JEAN-CLAUDE ,  BISCHOF DANIEL F

IPC: A61B5/15 ,  A61J1/14 ,  A61M1/02

CPC classification number: A61M1/0236 ,  A61B5/15 ,  A61B5/15003 ,  A61B5/150366 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150717 ,  A61B5/150755 ,  A61B5/150992 ,  A61B5/1545 ,  A61J1/12 ,  A61M1/0209

Abstract: Methods and apparatus for collecting blood samples in vacuum sample tubes are disclosed. The samples, including the initial blood sample, are substantially free of excess air. Disclosed is also a biological fluid sampling system (18) comprising: a plastic container (42) including an interior chamber (54); a sample access site (68) external to and spaced from said container by y preselected distance; an internal flow path (43) communicating with said access site and extending substantially into said interior chamber, said internal flow path providing the only path for blood flow into and from said chamber.

Abstract translation: 公开了用于在真空样品管中收集血样的方法和装置。 包括初始血液样本在内的样品基本上没有多余的空气。 公开了一种生物流体采样系统（18），包括：包括内部腔室（54）的塑料容器（42）; y预选距离在所述容器外部和与所述容器隔开的样品进入位置（68）; 与所述进入位置连通并且基本上延伸到所述内部腔室中的内部流动路径（43），所述内部流动路径提供用于血液流入和流出所述腔室的唯一途径。

公开(公告)号：WO0108546A3

公开(公告)日：2003-11-06

申请号：PCT/US0020580

申请日：2000-07-28

Applicant: BAXTER INT

Inventor： MATHIAS JEAN-MARIE ,  CONEYS THOMAS W

IPC: A61B5/15 ,  A61M1/02 ,  A61B19/00

CPC classification number: A61M1/0236 ,  A61B5/15003 ,  A61B5/150366 ,  A61B5/150572 ,  A61B5/150732 ,  A61B5/150992 ,  A61B5/154 ,  A61B5/155 ,  A61M1/0209 ,  Y10S604/905

Abstract: A holder (68) for receiving a sampling tube (70) of a blood sampling system is disclosed. The holder (68) has an interior pocket (81) which can be conformed from a closed position to an open position for receiving the sampling tube (70).

Abstract translation: 公开了一种用于接收采血系统的采样管（70）的支架（68）。 保持器（68）具有能够从闭合位置到打开位置的内部凹口（81），用于接收采样管（70）。

公开(公告)号：WO0174159A3

公开(公告)日：2002-02-28

申请号：PCT/US0109866

申请日：2001-03-27

Applicant: BAXTER INT

Inventor： BLOM AGNETA A ,  MATHIAS JEAN-MARIE ,  MESPREUVE LUC ,  PAYRAT JEAN-MARC ,  VANDENDAUL DANIEL

IPC: A61L2/04 ,  A61M1/02 ,  A61M1/36 ,  G01N33/49 ,  A61M37/00 ,  A61B19/00

CPC classification number: A61L2/04 ,  A61M1/0222 ,  A61M1/0227 ,  A61M1/0231 ,  A61M1/3633 ,  A61M1/3636 ,  A61M2202/0429 ,  A61M2205/60 ,  G01N33/491 ,  A61M2202/0092

Abstract: Systems and methods treat plasma by separating targeted blood cell species such as red blood cells and platelets from the plasma by filtration through hydrophilic polyvinylidene fluoride (PVDF) membranes.

Abstract translation: 系统和方法通过用亲水聚偏二氟乙烯（PVDF）膜过滤，从等离子体中分离目标血液细胞物质如红细胞和血小板来治疗血浆。

公开(公告)号：WO2004014457A3

公开(公告)日：2004-04-15

申请号：PCT/US0324825

申请日：2003-07-31

Applicant: BAXTER INT

Inventor： MATHIAS JEAN-MARIE

IPC: A61M20060101 ,  A61M5/00 ,  A61M5/32

CPC classification number: A61B5/153 ,  A61B5/15003 ,  A61B5/150259 ,  A61B5/150389 ,  A61B5/150519 ,  A61B5/150641 ,  A61B5/150916 ,  A61M5/3243 ,  A61M2005/3247

Abstract: Needle protectors (40) for housing used blood collection needles are disclosed. The needle protectors are single-piece protectors that include an open distal end (44) for receiving a needle hub (20) (with needle mounted thereon). A retaining member (60) locks the hub when the needle hub is fully retracted. A viewing slot (62) in one of the walls of the needle protector is provided.

Abstract translation: 公开了用于住房的采血针的针保护器（40）。 针保护器是单件保护器，其包括用于接收针座（20）的敞开的远端（44）（其上安装有针）。 当针座完全缩回时，保持构件（60）锁定轮毂。 提供了在针保护器的一个壁中的观察槽（62）。

公开(公告)号：WO0174158A3

公开(公告)日：2002-03-21

申请号：PCT/US0109865

申请日：2001-03-27

Applicant: BAXTER INT

Inventor： LYNN DANIEL R ,  VAN HEEMS PHILLIPPE ,  MUI TAT ,  BERNES JEAN-CLAUDE ,  DE VOS ROBERT ,  MATHIAS JEAN-MARIE

IPC: A61M1/02 ,  A61M1/36 ,  G01N33/49 ,  A61M37/00 ,  A61B19/00

CPC classification number: G01N33/491 ,  A61M1/0222 ,  A61M1/0227 ,  A61M1/0231 ,  A61M1/3633 ,  A61M1/3636

Abstract: Systems and methods collect leukocyte reduced blood components, including plasma that is free or virtually free of cellular blood species, such as red blood cells, platelets, and leukocytes.

Abstract translation: 系统和方法收集白细胞减少的血液成分，包括游离或基本上不含细胞血液的血浆，如红细胞，血小板和白细胞。

公开(公告)号：WO0136025A8

公开(公告)日：2001-11-01

申请号：PCT/US0030822

申请日：2000-11-10

Applicant: BAXTER INT

Inventor： MATHIAS JEAN-MARIE ,  VAN HEEMS PHILIPPE ,  DI STEFANI GIANNI ,  CONEYS THOMAS WALTER

IPC: A61M5/158 ,  A61M5/32 ,  A61M25/06 ,  A61M5/00

CPC classification number: A61M25/0631 ,  A61M5/3243 ,  A61M25/0612 ,  A61M2005/3246

Abstract: Needle protectors for retaining needles (12) are disclosed. The needle protector (40) includes a housing (42) with an opening (50, 48) at each of a proximal (46) and distal end (44). The needle protector (40) may include a portion that is depressable to a substantially fixed position over the needle (12) retracted within the housing (42).

Abstract translation: 公开了用于保持针（12）的针保护器。 针保护器（40）包括在近端（46）和远端（44）中的每一个处具有开口（50,48）的壳体（42）。 针保护器（40）可以包括可压缩到缩回到壳体（42）内的针（12）上的基本固定位置的部分。

公开(公告)号：EP0684796A4

公开(公告)日：1998-09-23

申请号：EP95905892

申请日：1994-12-09

Applicant: BAXTER INT

Inventor： DEBRAUWERE JACK ,  BERNES JEAN-CLAUDE ,  MATHIAS JEAN-MARIE

IPC: B65D33/36 ,  A61J1/00 ,  A61J1/10 ,  A61J1/12 ,  A61J1/14 ,  A61J1/20 ,  A61J3/00 ,  A61M1/02 ,  A61B19/00 ,  A61M37/00

CPC classification number: A61M1/0213 ,  A61J1/10 ,  A61J1/12 ,  A61M1/0209

Abstract: This invention is a container (46) for housing body fluids. The container comprises a body defined by flexible walls having an interior for housing the body fluid. An elongated tube (44) extends from the body for housing a fluid to be added to the body fluid. The tube includes means (18, 32) (see Fig.1) for allowing selective fluid flow from the interior of the tube to the interior of the body allowing the fluid to be added to the body fluid. Additionally, the means for allowing selective fluid flow allows the body fluid to be expressed from the body of the container into the elongated tube. The present invention also provides a method for storing and treating blood.

公开(公告)号：EP0650345A4

公开(公告)日：1995-06-28

申请号：EP94900351

申请日：1993-10-04

Applicant: BAXTER INT

Inventor： DEBRAUWERE JACK ,  MATHIAS JEAN-MARIE ,  PATEL INDRAJIT

IPC: A61J1/10 ,  A61J1/00 ,  A61J1/05 ,  A61J3/00 ,  A61L2/00 ,  A61L2/07 ,  A61B19/00 ,  A61M5/32

CPC classification number: A61J1/10 ,  A61K35/14 ,  A61L2/0023 ,  A61L2/0088 ,  A61L2/06 ,  A61L2/07 ,  A61L2/18 ,  C08L27/06 ,  C12N7/04

Abstract: A steam sterilizable unit for inactivating pathogens in a body fluid is provided including a plastic structure for housing a therapeutically effective amount of a methylene blue solution. The plastic structure preferably includes at least an inner layer constructed from a non-PVC plastic. Preferably, the methylene blue solution has a pH of less than 7.0 and preferably less than or equal to approximately 6.3.