公开(公告)号：AU2002361408A1

公开(公告)日：2003-07-09

申请号：AU2002361408

申请日：2002-12-13

Applicant: BAXTER INT ,  BAXTER HEALTHCARE SA

Inventor： SPRUTH MARTIN ,  MATTHIESSEN PETER ,  TURECEK PETER ,  KREIL THOMAS ,  SCHWARZ HANS-PETER ,  ANDERLE HEINZ

IPC: A61L2/00 ,  A61M1/36 ,  C12N7/06

Abstract: The present invention provides a method for inactivating pathogens in a protein solution. The method includes adding to the protein solution either separately or together as a composition (a) a detergent; and (b) an ester of a di- or tri-carboxylic acid to make a preparation. The ester is generally present in the preparation in a concentration of from about 0.001 to about 2% (w/w). The detergent is typically present in a concentration of about 0.001 to about 2% (w/w). The preparation is incubated for a sufficient amount of time sufficient to inactivate the pathogens.