公开(公告)号：US5470954C1

公开(公告)日：2001-02-06

申请号：US14069593

申请日：1993-10-21

Applicant: BAXTER TRAVENOL LAB

Inventor： NESLUND GERALD G ,  LIU SHU-LEN ,  GRIFFITH MICHAEL J

IPC: C07K14/435 ,  C07K1/16 ,  C07K1/18 ,  C07K1/20 ,  C07K1/22 ,  C07K14/745 ,  C07K14/755 ,  C07K14/76 ,  C07K14/775 ,  C07K16/00 ,  C12P21/00 ,  A61K35/16

CPC classification number: C07K14/755

公开(公告)号：DK184088A

公开(公告)日：1988-10-01

申请号：DK184088

申请日：1988-04-05

Applicant: BAXTER TRAVENOL LAB

Inventor： GRIFFITH MICHAEL J ,  NESLUND GERALD ,  LIU SHU-LEN

IPC: C07K1/16 ,  C07K14/435 ,  C07K1/18 ,  C07K1/20 ,  C07K1/22 ,  C07K14/745 ,  C07K14/755 ,  C07K14/76 ,  C07K14/775 ,  C07K16/00 ,  C12P21/00 ,  C07K3/18

Abstract: A process for purifying polypeptides comprising contacting an immobilized antibody specifically binding a polypeptide with that polypeptide, desorbing the polypeptide from the antibody which had adsorbed it, eluting the polypeptide from the presence of the antibody, passing the eluted polypeptide through an affinity region capable of binding the polypeptide, binding the polypeptide in the affinity region and passing contaminants through said region, and eluting the purified polypeptide.

公开(公告)号：DK184088D0

公开(公告)日：1988-04-05

申请号：DK184088

申请日：1988-04-05

Applicant: BAXTER TRAVENOL LAB

Inventor： GRIFFITH MICHAEL J ,  NESLUND GERALD ,  LIU SHU-LEN

IPC: C07K1/16 ,  C07K14/435 ,  C07K1/18 ,  C07K1/20 ,  C07K1/22 ,  C07K14/745 ,  C07K14/755 ,  C07K14/76 ,  C07K14/775 ,  C07K16/00 ,  C12P21/00 ,  C07K3/18

Abstract: A process for purifying polypeptides comprising contacting an immobilized antibody specifically binding a polypeptide with that polypeptide, desorbing the polypeptide from the antibody which had adsorbed it, eluting the polypeptide from the presence of the antibody, passing the eluted polypeptide through an affinity region capable of binding the polypeptide, binding the polypeptide in the affinity region and passing contaminants through said region, and eluting the purified polypeptide.