公开(公告)号：DE1767285A1

公开(公告)日：1971-08-19

申请号：DE1767285

申请日：1968-04-22

Applicant: BAXTER TRAVENOL LAB ,  BAXTER LABORATORIES INC

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K17/00

公开(公告)号：JPS594402B1

公开(公告)日：1984-01-30

申请号：JP11429473

申请日：1973-10-11

Applicant: Baxter Travenol Lab

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K35/16

CPC classification number: C07K14/755 ,  A61K38/00

公开(公告)号：DE1767285C3

公开(公告)日：1981-08-20

申请号：DE1767285

申请日：1968-04-22

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K35/16

公开(公告)号：NL162838C

公开(公告)日：1980-07-15

申请号：NL6806162

申请日：1968-05-01

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K35/16

公开(公告)号：CA1009575A

公开(公告)日：1977-05-03

申请号：CA171779

申请日：1973-05-18

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD ,  LOUDERBACK ALLAN L

IPC: G01N33/72

Abstract: A microcapillary method for the diagnosis of sickle-cell disease in which a sample of unclotted blood is mixed with a reagent comprising phosphate buffer containing a non-ionic surfactant having high water solubility, a hemolyzing agent and a reducing agent, and the reaction results observed macroscopically for turbidity and then a microcapillary sample thereof observed macroscopically for color characteristics.

公开(公告)号：BE713764A

公开(公告)日：1968-09-16

申请号：BE713764D

申请日：1968-04-17

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755

公开(公告)号：NL162838B

公开(公告)日：1980-02-15

申请号：NL6806162

申请日：1968-05-01

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K35/16

公开(公告)号：DE1767285B2

公开(公告)日：1980-12-04

申请号：DE1767285

申请日：1968-04-22

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755 ,  A61K35/16

公开(公告)号：FR1589414A

公开(公告)日：1970-03-31

申请号：FR1589414D

申请日：1968-04-23

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755

公开(公告)号：GB1178958A

公开(公告)日：1970-01-28

申请号：GB2060468

申请日：1968-05-01

Applicant: BAXTER TRAVENOL LAB

Inventor： SHANBROM EDWARD

IPC: A61K35/14 ,  A61K38/00 ,  A61P7/00 ,  C07K14/755

Abstract: 1,178,958. Concentrating A.H.F. BAXTER LABORATORIES Inc. 1 May, 1968 [1 May, 1967], No. 20604/68. Heading A5B. Antihemophilic Factor (A.H.F.) is obtained in more concentrated form by precipitating a redissolved cryoprecipitate of A.H.F. with aqueous glycine and/or polyethylene solutions. The cryoprecipitate may be formed by cooling human blood plasma e.g. to -20‹C to -40‹C followed by slow thawing to about 4‹C. The precipitate is dissolved in glycine citrated saline and the precipitant is added. The precipitate is collected and may be redissolved and reprecipitated using the other precipitant and/or subjected to an additional purification step by adsorption on and ellution from a chromatographic column of "Eoteola" cellulose resin.