公开(公告)号：JPS62212378A

公开(公告)日：1987-09-18

申请号：JP5040287

申请日：1987-03-06

Applicant: BAYER AG

Inventor： JIIKUFURIITO RADATSUTSU ,  HANSU PURIYUNPE ,  ROMANISU FURUFUTOMAN ,  KURISUCHIYAN KOORUSUDORUFUAA ,  BERUNHARUTO PERUSUTAA

IPC: C12N9/99 ,  A61K31/425 ,  A61K31/426 ,  A61P7/02 ,  A61P7/10 ,  A61P9/00 ,  A61P9/10 ,  A61P11/00 ,  A61P17/00 ,  A61P29/00 ,  A61P37/08 ,  A61P43/00 ,  C07D277/18 ,  C07D277/20 ,  C07D277/42 ,  C07D277/44 ,  C07D279/06

公开(公告)号：JPS62148490A

公开(公告)日：1987-07-02

申请号：JP29683186

申请日：1986-12-15

Applicant: BAYER AG

Inventor： AREKUSANDAA KURAUZENAA ,  GERUTO FUENGURAA ,  HANSU YOZEFU BUISHIYU ,  BERUNHARUTO PERUSUTAA

IPC: A61K31/54 ,  A61P9/10 ,  A61P29/00 ,  A61P37/08 ,  C07D513/04

公开(公告)号：JPS61137878A

公开(公告)日：1986-06-25

申请号：JP26515685

申请日：1985-11-27

Applicant: Bayer Ag

Inventor： KURAUSU SATSUSE ,  MAIKERU HAMONDO ,  FURIIDERU ZOITAA ,  ERIIZABETO PERUTSUBORUN ,  BERUNHARUTO PERUSUTAA ,  GURAHAMU SUTAATON ,  TOREBAA ABURAMU

IPC: C07D213/77 ,  A61K31/44 ,  A61K31/4402 ,  A61K31/4406 ,  A61K31/4409 ,  A61K31/4412 ,  A61K31/4418 ,  A61K31/4427 ,  A61K31/443 ,  A61K31/505 ,  A61P7/02 ,  A61P29/00 ,  A61P37/08 ,  C07D231/22 ,  C07D251/46 ,  C07D317/00 ,  C07D401/04 ,  C07D403/04 ,  C07D405/14 ,  C12N9/99

CPC classification number: C07D401/04 ,  C07D403/04 ,  C07D405/14

公开(公告)号：JPS62120389A

公开(公告)日：1987-06-01

申请号：JP26997186

申请日：1986-11-14

Applicant: BAYER AG

Inventor： GERUTO FUENGURAA ,  AREKUSANDAA KURAUZENAA ,  HANSU YOZEFU BUISHIYU ,  MITATO MARUDEIN ,  BERUNHARUTO PERUSUTAA

IPC: A61K31/54 ,  A61P11/00 ,  A61P29/00 ,  A61P37/08 ,  C07D513/04

Abstract: New potent lipoxygenase inhibitors which are 1H-pyrido-[2,3-b][1,4] thiazines are disclosed. The new thiazines are of the formula in which R1 denotes hydrogen, halogen, optionally substituted alkyl or alkoxy or the group in which R5 and R6 are identical or different and denote hydrogen, optionally substituted alkyl or aryl, or can be linked to form a 5- or 6-membered heterocyclic ring, R2 and R3 are identical or different and denote hydrogen or optionally substituted alkyl or alkoxy and R4 denotes hydroxyl, the group in which R5 and R6 have the abovementioned meaning, or, in the case where R3 denotes hydrogen or optionally substituted alkoxy, also denotes optionally substituted alkoxy.