公开(公告)号：WO1994022585A1

公开(公告)日：1994-10-13

申请号：PCT/US1994003596

申请日：1994-04-01

Applicant: BECKMAN INSTRUMENTS, INC.

Inventor： BECKMAN INSTRUMENTS, INC. ,  MOORE, Patrick, Q. ,  SCHIESSLER, David, L.

IPC: B04B05/04

CPC classification number: B65D39/0088 ,  B01L3/5021 ,  B04B5/0414 ,  B65D2539/006

Abstract: The present invention directed to a plug (16) for sealing a centrifuge tube (10). The plug (16) of the present invention is shaped and sized to provide an interference fit between the plug (16) and the tube stem (12) of the centrifuge tube. In the described embodiment, the plug is configured with a tapered body narrowing to a flared end (22). To facilitate the insertion and removal of the plug with moderate force, without compromising the restraining capability of the interference fit, the area of interference contact between the flared end and the filler stem is strategically reduced. An o-ring is provided in an annular groove (20) around the tapered body. The flared end (22) creates an interference fit with a tapered filler stem (12) whereby the plug (16) is secured in the filler stem (12) with a snapping action when the flared end (22) of the plug (16) extends into the tube beyond the tapered filler stem (12). In this snap-in position, the plug (16) is secured in the filler stem (12), providing an initial seal; such seal increases upon centrifugation by a self-sealing mechanism, either attributed to the internal hydrostatic pressure in the tube and/or the force of a support spacer on the plug. After centrifugation, the snap coupling between the filler stem and the plug securely retains the plug against any residual internal pressure built up within the tube created by deformation of the centrifuge tube either from centrifugation or through handling of the tube by the user.

Abstract translation: 本发明涉及用于密封离心管（10）的塞子（16）。 本发明的插头（16）的形状和尺寸被设计成提供离心管的插塞（16）和管杆（12）之间的过盈配合。 在所描述的实施例中，插头构造成具有朝向扩张端（22）变窄的锥形体。 为了有利于以适度的力插入和移除插头，在不影响过盈配合的约束能力的情况下，战略上减少了扩口端与加注杆之间的干涉接触面积。 O形圈设置在围绕锥形主体的环形槽（20）中。 扩口端（22）产生与锥形填充杆（12）的过盈配合，由此当插头（16）的扩口端（22）具有卡扣动作时，插头（16）固定在填充杆（12） 延伸到超过锥形填充杆（12）的管中。 在该卡入位置中，插头（16）固定在加注杆（12）中，提供初始密封; 这种密封通过自密封机构进行离心时增加，归因于管中的内部静水压力和/或插塞上的支撑间隔件的力。 离心后，填充杆和插塞之间的卡扣联结可以牢固地保持插塞抵抗由离心管变形而产生的管内的任何残余内部压力，或者离心或通过使用者处理管。

公开(公告)号：EP0643629B1

公开(公告)日：1997-03-12

申请号：EP94913343.3

申请日：1994-04-01

Applicant: BECKMAN INSTRUMENTS, INC.

Inventor： MOORE, Patrick, Q. ,  SCHIESSLER, David, L.

IPC: B04B5/04 ,  B01L3/14

CPC classification number: B65D39/0088 ,  B01L3/5021 ,  B04B5/0414 ,  B65D2539/006

Abstract: The present invention directed to a plug (16) for sealing a centrifuge tube (10). The plug (16) of the present invention is shaped and sized to provide an interference fit between the plug (16) and the tube stem (12) of the centrifuge tube. In the described embodiment, the plug is configured with a tapered body narrowing to a flared end (22). To facilitate the insertion and removal of the plug with moderate force, without compromising the restraining capability of the interference fit, the area of interference contact between the flared end and the filler stem is strategically reduced. An o-ring is provided in an annular groove (20) around the tapered body. The flared end (22) creates an interference fit with a tapered filler stem (12) whereby the plug (16) is secured in the filler stem (12) with a snapping action when the flared end (22) of the plug (16) extends into the tube beyond the tapered filler stem (12). In this snap-in position, the plug (16) is secured in the filler stem (12), providing an initial seal; such seal increases upon centrifugation by a self-sealing mechanism, either attributed to the internal hydrostatic pressure in the tube and/or the force of a support spacer on the plug. After centrifugation, the snap coupling between the filler stem and the plug securely retains the plug against any residual internal pressure built up within the tube created by deformation of the centrifuge tube either from centrifugation or through handling of the tube by the user.

公开(公告)号：EP0643629A1

公开(公告)日：1995-03-22

申请号：EP94913343.0

申请日：1994-04-01

Applicant: BECKMAN INSTRUMENTS, INC.

Inventor： MOORE, Patrick, Q. ,  SCHIESSLER, David, L.

IPC: B04B5 ,  B01L3

CPC classification number: B65D39/0088 ,  B01L3/5021 ,  B04B5/0414 ,  B65D2539/006

Abstract: The present invention directed to a plug (16) for sealing a centrifuge tube (10). The plug (16) of the present invention is shaped and sized to provide an interference fit between the plug (16) and the tube stem (12) of the centrifuge tube. In the described embodiment, the plug is configured with a tapered body narrowing to a flared end (22). To facilitate the insertion and removal of the plug with moderate force, without compromising the restraining capability of the interference fit, the area of interference contact between the flared end and the filler stem is strategically reduced. An o-ring is provided in an annular groove (20) around the tapered body. The flared end (22) creates an interference fit with a tapered filler stem (12) whereby the plug (16) is secured in the filler stem (12) with a snapping action when the flared end (22) of the plug (16) extends into the tube beyond the tapered filler stem (12). In this snap-in position, the plug (16) is secured in the filler stem (12), providing an initial seal; such seal increases upon centrifugation by a self-sealing mechanism, either attributed to the internal hydrostatic pressure in the tube and/or the force of a support spacer on the plug. After centrifugation, the snap coupling between the filler stem and the plug securely retains the plug against any residual internal pressure built up within the tube created by deformation of the centrifuge tube either from centrifugation or through handling of the tube by the user.