Abstract:
1,130,427. Electro-phoretic separation of substances. BECKMAN INSTRUMENTS Inc. Aug. 31, 1966 [Dec.8, 1965], No. 38744/66. Heading C7B. In an apparatus for the continuous separation of substances by electro-phoresis comprising parallel plates 10, 12 defining an interspace 16 therebetween, an electrolyte inlet 28, discharging means 22, 24; means 48 for injecting a sample into the flow of electrolyte and a means 52 for withdrawing a component of the sample, the electrolyte withdrawing means comprises a plurality of ports having adjustable flow means connected thereto such that by adjusting the relative flow rate of electrolyte discharged via each port, the electrolyte flow sheet may be shifted laterally with respect to the interspace such that any selected sample component may be removed via the sample removal tube 52. As shown the interspace is formed by positioning a membrane 14 between the plates 10, 12, the membrane having an opening 16 cut therein, said opening having an apex 18 at which point the electrolyte is introduced, and having lower extremities 22 and 24 where the electrolyte outlets 34, 36 are situated. The adjustable flow means controlling the electrolyte discharge may comprise valves 54, 56 or reservoirs (74), (76) connected to the electrolyte outlets, the height of the reservoirs being adjustable, Fig. 4 (not shown). The membrane 14 becomes saturated with electrolyte and the electrodes 38, 40 are attached thereto.