公开(公告)号：EP3189004A4

公开(公告)日：2018-03-07

申请号：EP15838966

申请日：2015-08-25

Applicant: BIO-RAD LABORATORIES INC

Inventor： WAN ALWIN ,  SADRI AMIR ,  ROSENZWEIG TAL ,  KIRCANSKI NENAD ,  YOUNG EDMOND

IPC: B01L3/00 ,  B29C65/00 ,  B29C65/48 ,  B29L31/00 ,  B81B1/00 ,  B81C3/00

CPC classification number: B01L3/502707 ,  B01L2200/025 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2200/16 ,  B01L2300/08 ,  B01L2300/0816 ,  B01L2300/0864 ,  B01L2300/0887 ,  B29C65/4895 ,  B29C66/1122 ,  B29C66/45 ,  B29C66/53461 ,  B29C66/71 ,  B29C66/73921 ,  B29L2031/756 ,  B81B1/00 ,  B81B2201/058 ,  B81B2203/0338 ,  B81C3/001 ,  B81C2203/032 ,  B81C2203/036 ,  B81C2203/057 ,  B29K2033/12 ,  B29K2069/00 ,  B29K2025/06

Abstract: Microscale fluidic devices and components thereof having a fluid retention groove, as well as systems and methods related thereto. The fluid retention groove facilitates uniform bonding of microfluidic device components.

公开(公告)号：EP3186191A4

公开(公告)日：2018-02-07

申请号：EP15835781

申请日：2015-08-28

Applicant: BIO-RAD LABORATORIES INC

Inventor： KONSTANTINOU DANIEL ,  WAN ALWIN ,  ROSENZWEIG TAL ,  SADRI AMIR ,  KIRCANSKI NENAD ,  YOUNG EDMOND

IPC: B29C43/02 ,  B01L3/00 ,  B29C33/38 ,  B29C33/40 ,  B29C39/02 ,  B29K33/00 ,  B81C1/00

CPC classification number: B01L3/502707 ,  B01L2300/0816 ,  B29C33/3878 ,  B29C33/40 ,  B29C39/026 ,  B29K2033/12 ,  B29K2883/00

Abstract: A method for efficiently manufacturing and fabricating microfluidic chips, where a base mold is formed to have positive-relief features used to cast an intermediary template chip with negative-relief features having dimensions of a scale in the micron range. The intermediary template chip is used to case a production mold, which is formed of a reinforced epoxy resin that, once hardened into a solid epoxy member, can withstand the structural pressures of a CNC machining system. The production mold can be refined by a CNC machining, where the refined production mold is then used to cast production chips to be used as microfluidic chips.