公开(公告)号：JP2014158474A

公开(公告)日：2014-09-04

申请号：JP2014061610

申请日：2014-03-25

Applicant: Basf Se ,  ビーエーエスエフ ソシエタス・ヨーロピアBasf Se

Inventor： SCHOLTEN EDZARD ,  DIRK DAEGELE ,  HAEFNER STEFAN ,  SCHROEDER HARTWIG

IPC: C12N1/20 ,  C12P7/00 ,  C12P7/18 ,  C12P7/24 ,  C12P7/46

CPC classification number: C12P7/46 ,  C12N1/32 ,  C12R1/01

Abstract: PROBLEM TO BE SOLVED: To provide: a novel bacterial strain designated DD1, which has the ability to produce organic acids, in particular, succinic acid (SA), which has been isolated from bovine rumen, and is capable of utilizing glycerol as a carbon source; and variant strains thereof.SOLUTION: The invention provides a process for producing succinic acid by cultivating a microorganism in the presence of glycerol, glucose, fructose, maltose, sucrose, or the like. The invention also provides a process for the production of tetrahydrofuran and/or 1,4-butanediol and/or γ-butyrolactone, and pyrrolidone from succinic acid. The microorganism is Mannheimia succiniciproducens MBEL belonging to genus Mannheimia, and is a Gram-negative bacillus or coccobacillus.

Abstract translation: 要解决的问题：提供：一种称为DD1的新型细菌菌株，其具有产生有机酸的能力，特别是已经从牛瘤胃中分离的琥珀酸（SA），并且能够利用甘油作为碳 资源; 其变体菌株。本发明提供了通过在甘油，葡萄糖，果糖，麦芽糖，蔗糖等存在下培养微生物来生产琥珀酸的方法。 本发明还提供从琥珀酸生产四氢呋喃和/或1,4-丁二醇和/或γ-丁内酯和吡咯烷酮的方法。 微生物是Mannheimia succiniciproducens MBEL属于Mannheimia属，是革兰氏阴性杆菌或coccobacillus。