中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

4 records (took 0.03 seconds)

    Pharmaceutical formulation for producing rapidly disintegrating tablets
    1.
    发明专利
    Pharmaceutical formulation for producing rapidly disintegrating tablets 审中-公开
    用于生产快速消毒片的药物制剂

    公开(公告)号：JP2014114322A

    公开(公告)日：2014-06-26

    申请号：JP2014031168

    申请日：2014-02-21

    Applicant: Basf Se ,  ビーエーエスエフ ソシエタス・ヨーロピアBasf Se

    Inventor： KOLTER KARL ,  MICHAEL SCHOENHERR ,  SILKE GEBERT ,  KATHRIN MEYER-BOHM ,  ANGELIKA MASCHKE

    IPC: A61K9/26 ,  A61K47/10 ,  A61K47/20 ,  A61K47/32 ,  A61K47/38

    CPC classification number: A61K9/2018 ,  A61K9/0056 ,  A61K9/2027 ,  A61K9/2054

    Abstract: PROBLEM TO BE SOLVED: To provide tablets which disintegrate rapidly in the mouth, leave behind a pleasant sensation in the mouth, are mechanically very stable, and provide high content uniformity.SOLUTION: A pharmaceutical formulation in the form of agglomerates comprises the following components A) and B): A) an excipient consisting of a) 60-97% by weight of sugar or sugar alcohols, b) 1-25% by weight of a disintegration agent, c) 1-15% by weight of water-insoluble, film-forming polymers, d) 0-15% by weight of water-soluble polymers, and e) 0-15% by weight of another pharmaceutically customary excipients, wherein the sum of the components a) to e) is 100% by weight; and B) at least one active ingredient.

    Abstract translation: 要解决的问题：提供在口中快速崩解的片剂，在口中留下愉快的感觉，机械上非常稳定，并提供高含量均匀性。溶解剂：附聚物形式的药物制剂包含以下组分A ）和B）：A）由a）60-97重量％的糖或糖醇组成的赋形剂，b）1-25重量％的崩解剂，c）1-15重量％的水不溶性 ，成膜聚合物，d）0-15重量％的水溶性聚合物，和e）0-15重量％的另一种药学上常规的赋形剂，其中组分a）至e）的总和为100％ 重量; 和B）至少一种活性成分。

    METHOD FOR PRODUCING A SPRAY POWDER CONTAINING ONE OR MORE GLYCINE-N,N-DIACETIC ACID DERIVATIVES AND USE OF THE SPRAY POWDER TO PRODUCE COMPRESSION AGGLOMERATES
    3.
    发明专利
    METHOD FOR PRODUCING A SPRAY POWDER CONTAINING ONE OR MORE GLYCINE-N,N-DIACETIC ACID DERIVATIVES AND USE OF THE SPRAY POWDER TO PRODUCE COMPRESSION AGGLOMERATES 未知

    公开(公告)号：MY153903A

    公开(公告)日：2015-04-15

    申请号：MYPI2011005601

    申请日：2010-05-19

    Applicant: BASF SE

    Inventor： FRANK MRZENA ,  MICHAEL SCHOENHERR ,  ROBERT HEINZ ,  THOMAS HEIDENFELDER

    IPC: B01J2/16

    Abstract: THE INVENTION RELATES TO A METHOD FOR PRODUCING A SPRAY POWDER CONTAINING ONE OR MORE GLYCINE-N, N-DIACETIC ACID DERIVATIVES OF THE GENERAL FORMULA (I) MOOC-CHR-N(CH2COOM)2 (I), R STANDING FOR C1-12 ALKYL AND M STANDING FOR ALKALI METAL, STARTING FROM AN AQUEOUS SOLUTION CONTAINING THE ONE OR MORE GLYCINE-N, N-DIACETIC ACID DERIVATIVES, WHICH IS SPRAY-DRIED BY ADDING AIR, CHARACTERIZED IN THAT - THE AQUEOUS SOLUTION CONTAINS THE ONE OR MORE GLYCINE-N, N-DIACETIC ACID DERIVATIVES AT A FRACTION OF ? 84 WT.% RELATIVE TO THE TOTAL WEIGHT OF THE DRY MASS, AND THAT - THE SPRAY DRYING OCCURS IN A DRYING APPARATUS, TO WHICH THE AQUEOUS SOLUTION AND THE AIR ARE FED IN PARALLEL FLOW, WITH A TEMPERATURE GRADIENT BETWEEN THE AQUEOUS SOLUTION AND THE AIR IN THE RANGE OF 70 TO 350 °C, AND THAT - IN THE DRYING APPARATUS, THE AQUEOUS SOLUTION IS ATOMIZED INTO FINE LIQUID DROPLETS BY BEING GUIDED ONTO ONE OR MORE DISKS, WHICH ROTATE AT A CIRCUMFERENTIAL SPEED OF ? 100 M/S, OR BY BEING COMPRESSED BY MEANS OF A PUMP TO A PRESSURE OF ? 20 BAR ABSOLUTE AND INTRODUCED INTO THE DRYING APPARATUS AT THIS PRESSURE BY MEANS OF ONE OR MORE NOZZLES.

Patent Agency Ranking