公开(公告)号：US20200179929A1

公开(公告)日：2020-06-11

申请号：US16596688

申请日：2019-10-08

Applicant: Bioelectronica Corporation

Inventor： Leonard SHERMAN ,  Roger CHEN ,  Jonathan F. HULL

IPC: B01L3/00 ,  G01N15/14

Abstract: A system for processing a sample includes a chamber having at least one inlet and at least one outlet, where the chamber is configured to accommodate flow of the sample from the at least one inlet toward the at least one outlet, and an imager array configured to image the flow of the sample in the chamber, where the imager array includes at least one lensless image sensor configurable opposite at least one light source.

公开(公告)号：US20180333724A1

公开(公告)日：2018-11-22

申请号：US15986416

申请日：2018-05-22

Applicant: Bioelectronica Corporation

Inventor： Jonathan F. HULL ,  Martin TOMASZ ,  Roger CHEN

IPC: B01L3/00 ,  C12Q1/02 ,  G01N27/22

CPC classification number: B01L3/502784 ,  B01L2200/14 ,  B01L2300/0645 ,  B01L2300/0819 ,  B01L2400/0424 ,  B03C2201/00 ,  C12Q1/02 ,  G01N27/221

Abstract: A system for processing sample entities includes a chamber including a surface having an array of measurement regions, wherein at least one measurement region comprises a first set of one or more electrodes and a second set of one or more electrodes, wherein the first set of electrodes is configured to measure a first characteristic of a sample entity when the sample entity is traversing the first set of electrodes, and wherein the second set of electrodes is configured to selectively retain the sample entity in the at least one measurement region based at least in part on the measured first characteristic and/or measure a second characteristic of the sample entity.

公开(公告)号：US20220331801A1

公开(公告)日：2022-10-20

申请号：US17534879

申请日：2021-11-24

Applicant: Bioelectronica Corporation

Inventor： Leonard SHERMAN ,  Roger CHEN ,  Jonathan F. HULL

IPC: B01L3/00 ,  G01N15/14 ,  G01N15/02 ,  G01N33/483

Abstract: A system for processing a sample includes a chamber having at least one inlet and at least one outlet, where the chamber is configured to accommodate flow of the sample from the at least one inlet toward the at least one outlet, and an imager array configured to image the flow of the sample in the chamber, where the imager array includes at least one lensless image sensor configurable opposite at least one light source.

公开(公告)号：US20200158628A1

公开(公告)日：2020-05-21

申请号：US16660377

申请日：2019-10-22

Applicant: Bioelectronica Corporation

Inventor： Roger CHEN ,  Jonathan F. HULL

IPC: G01N21/17 ,  G01N21/88 ,  G01N21/64

Abstract: A system for processing a sample includes a chamber for receiving a sample, at least one light source, and an imager array configured to generate a sample image of the sample in the chamber. The system can be used to process a sample in a multiplexed manner. For example, one variation of a method for processing a sample includes identifying one or more features of interest in the sample based at least in part on the forms and/or darkness shift of one or more marker particles depicted in the sample image. Another variation of a method includes illuminating the sample with light having a wavelength outside a wavelength detection window of the imager array, to thereby induce at least a portion of the sample to fluoresce light within the wavelength detection window.