公开(公告)号：WO2003102535A3

公开(公告)日：2003-12-11

申请号：PCT/US2003/016367

申请日：2003-05-23

Applicant: BIOMICROARRAYS INC ,  AGRAWAL, Anoop ,  GOODYEAR, Alan, Gordon ,  TONAZZI, Juan, Carlos, Lopez ,  LECOMPTE, Robert, S.

Inventor： AGRAWAL, Anoop ,  GOODYEAR, Alan, Gordon ,  TONAZZI, Juan, Carlos, Lopez ,  LECOMPTE, Robert, S.

IPC: C12M1/34

Abstract: This invention describes the advantages of forming integrated biochips including microarrays comprised of tiled assemblies. For a given biochip of this invention, the tiles may have similar or dissimilar properties. Novel, high-speed manufacturing processes are described to assemble such biochips. A preferred embodiment is the use of micro-machined feeders for placing the tiles in the assembly process.

公开(公告)号：WO2003046508A3

公开(公告)日：2003-06-05

申请号：PCT/US2002/035952

申请日：2002-11-08

Applicant: BIOMICROARRAYS, INC. ,  AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan Carlos Lopez ,  GOODYEAR, A., Gordon ,  LECOMPTE, Robert, S. ,  HOGAN, Michael, E. ,  GALBRAITH, David, W.

Inventor： AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan Carlos Lopez ,  GOODYEAR, A., Gordon ,  LECOMPTE, Robert, S. ,  HOGAN, Michael, E. ,  GALBRAITH, David, W.

IPC: G01N33/543

Abstract: The present invention is directed to a substrate having a plurality of microfeatures that provide a high surface area and are open to provide ready access to fluids and components therein. Methods of making the high surface area substrates are described and include generating microfeatures and/or microstructures on the surface of the substrate.

公开(公告)号：WO2003102535A2

公开(公告)日：2003-12-11

申请号：PCT/US2003/016367

申请日：2003-05-23

Applicant: BIOMICROARRAYS INC ,  AGRAWAL, Anoop ,  GOODYEAR, Alan, Gordon ,  TONAZZI, Juan, Carlos, Lopez ,  LECOMPTE, Robert, S.

Inventor： AGRAWAL, Anoop ,  GOODYEAR, Alan, Gordon ,  TONAZZI, Juan, Carlos, Lopez ,  LECOMPTE, Robert, S.

IPC: G01N

CPC classification number: B01J19/0093 ,  B01J19/0046 ,  B01J2219/00382 ,  B01J2219/00468 ,  B01J2219/00475 ,  B01J2219/005 ,  B01J2219/00527 ,  B01J2219/00644 ,  B01J2219/00648 ,  B01J2219/00653 ,  B01J2219/00659 ,  B01J2219/00804 ,  B01J2219/0081 ,  B01J2219/00867 ,  B01J2219/00869 ,  C40B60/14

Abstract: This invention describes the advantages of forming integrated biochips including microarrays comprised of tiled assemblies. For a given biochip of this invention, the tiles may have similar or dissimilar properties. Novel, high-speed manufacturing processes are described to assemble such biochips. A preferred embodiment is the use of micro-machined feeders for placing the tiles in the assembly process.

Abstract translation: 本发明描述了形成集成生物芯片的优点，包括由平铺组件组成的微阵列。 对于本发明的给定生物芯片，瓷砖可以具有相似或不相似的性质。 描述了新颖的高速制造工艺来组装这样的生物芯片。 优选的实施例是使用微加工的进料器将瓦片放置在组装过程中。

公开(公告)号：WO2003046508A2

公开(公告)日：2003-06-05

申请号：PCT/US2002/035952

申请日：2002-11-08

Applicant: BIOMICROARRAYS, INC. ,  AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan Carlos Lopez ,  GOODYEAR, A., Gordon ,  LECOMPTE, Robert, C. ,  HOGAN, Michael, E. ,  GALBRAITH, David, W.

Inventor： AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan Carlos Lopez ,  GOODYEAR, A., Gordon ,  LECOMPTE, Robert, C. ,  HOGAN, Michael, E. ,  GALBRAITH, David, W.

IPC: G01N

CPC classification number: B81C1/00206 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00378 ,  B01J2219/00387 ,  B01J2219/00504 ,  B01J2219/00527 ,  B01J2219/00574 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00621 ,  B01J2219/00628 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00734 ,  B01J2219/00743 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2200/12 ,  B01L2300/0819 ,  B01L2300/16 ,  B01L2300/166 ,  B81B1/006 ,  B81B2201/0214

Abstract: The present invention is directed to a substrate having a plurality of microfeatures that provide a high surface area and are open to provide ready access to fluids and components therein. Methods of making the high surface area substrates are described and include generating microfeatures and/or microstructures on the surface of the substrate.

Abstract translation: 本发明涉及一种具有多个微特征的基底，其提供高的表面积并且是开放的以提供对其中的流体和组分的准备进入。 描述了制造高表面积基板的方法，包括在基板的表面上产生微特征和/或微结构。

公开(公告)号：EP1451584A2

公开(公告)日：2004-09-01

申请号：EP02795610.1

申请日：2002-11-08

Applicant: Biomicroarrays, Inc.

Inventor： AGRAWAL, Anoop ,  CRONIN, John, P. ,  TONAZZI, Juan Carlos Lopez ,  GOODYEAR, A., Gordon ,  LECOMPTE, Robert, S. ,  HOGAN, Michael, E. ,  GALBRAITH, David, W.

IPC: G01N33/543 ,  G01N21/00 ,  G01N31/00 ,  G01N15/06 ,  G05B1/00

CPC classification number: B81C1/00206 ,  B01J19/0046 ,  B01J2219/00317 ,  B01J2219/00378 ,  B01J2219/00387 ,  B01J2219/00504 ,  B01J2219/00527 ,  B01J2219/00574 ,  B01J2219/00576 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00617 ,  B01J2219/00621 ,  B01J2219/00628 ,  B01J2219/00635 ,  B01J2219/00637 ,  B01J2219/00644 ,  B01J2219/00659 ,  B01J2219/00677 ,  B01J2219/00722 ,  B01J2219/00725 ,  B01J2219/00734 ,  B01J2219/00743 ,  B01L3/5085 ,  B01L3/5088 ,  B01L2200/12 ,  B01L2300/0819 ,  B01L2300/16 ,  B01L2300/166 ,  B81B1/006 ,  B81B2201/0214

Abstract: The present invention is directed to a substrate having a plurality of microfeatures that provide a high surface area and are open to provide ready access to fluids and components therein. Methods of making the high surface area substrates are described and include generating microfeatures and/or microstructures on the surface of the substrate.