公开(公告)号：WO2005071414A3

公开(公告)日：2006-03-02

申请号：PCT/JP2005001316

申请日：2005-01-25

Applicant: CANON KK ,  BAN KAZUHIRO ,  SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI

Inventor： BAN KAZUHIRO ,  SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI

IPC: C12N11/14 ,  G01N33/543 ,  C07K7/06 ,  C07K7/08 ,  C12N15/09 ,  G01N33/551

CPC classification number: G01N33/54353 ,  G01N33/551

Abstract: To provide an organic substance-immobilized structure employing a novel immobilizing technique and a manufacturing method thereof using the novel immobilizing technique, where, when an organic substance, particularly a biological substance is immobilized on the surface of a substrate, the organic substance, particularly the biological substance can be stably immobilized on the surface of the substrate through orientation of the organic substance, particularly the biological substance suitable for exerting physiological functions thereof. At least part of the substrate's surface is constructed of one or more substrates containing aluminum oxide. The immobilization of the organic substance to the surface of the substrate is carried out by binding at least part of the binding domain to the surface of the substrate through a binding domain containing a peptide having an affinity to aluminum oxide and composed of at least one or more amino acids, which is coupled with the organic substance.

Abstract translation: 为了提供采用新型固定化技术的有机物质固定化结构及其制造方法，其中，当将有机物质，特别是生物物质固定在基材表面上时，有机物质，特别是 生物物质可以通过有机物质，特别是适于发挥其生理功能的生物物质的取向，稳定地固定在基材的表面上。 衬底表面的至少一部分由含有氧化铝的一个或多个衬底构成。 有机物质固定到底物的表面是通过结合结构域与底物的表面结合而进行的，所述结合结构域含有与氧化铝具有亲和性的肽，并且由至少一个或多个 更多的氨基酸，其与有机物质偶联。

公开(公告)号：WO2005003715A3

公开(公告)日：2005-05-26

申请号：PCT/JP2004009788

申请日：2004-07-02

Applicant: CANON KK ,  HASHIMOTO HIROYUKI ,  KUGE KATSUAKI ,  KOMATSU MANABU ,  NAKAMURA KUMI ,  BAN KAZUHIRO ,  IMAMURA TAKESHI ,  KOBAYASHI SHIN

Inventor： HASHIMOTO HIROYUKI ,  KUGE KATSUAKI ,  KOMATSU MANABU ,  NAKAMURA KUMI ,  BAN KAZUHIRO ,  IMAMURA TAKESHI ,  KOBAYASHI SHIN

IPC: G01N33/68 ,  H01J49/04 ,  H01J49/40

CPC classification number: G01N33/6848 ,  H01J49/04 ,  H01J49/40

Abstract: An information acquisition method for acquiring information on a target object, that includes a step of promoting ionization of the target object using a substance for promoting ionization of the target object to cause the target object to emit, and a step of acquiring information on the mass of the flew target object using time-of-flight secondary ion mass spectrometry.

Abstract translation: 一种用于获取关于目标对象的信息的信息获取方法，其包括使用促进所述目标对象的电离的物质促进所述目标对象的电离以使所述目标对象发射的步骤以及获取所述质量信息的步骤 的飞行目标物体使用飞行时间二次离子质谱法。

公开(公告)号：WO2004097417A8

公开(公告)日：2005-01-13

申请号：PCT/JP2004006420

申请日：2004-05-06

Applicant: CANON KK ,  IMAMURA TAKESHI ,  YANO TETSUYA ,  HONMA TSUTOMU ,  KOZAKI SHINYA ,  NOMOTO TSUYOSHI ,  TSUCHITANI AKIKO

Inventor： IMAMURA TAKESHI ,  YANO TETSUYA ,  HONMA TSUTOMU ,  KOZAKI SHINYA ,  NOMOTO TSUYOSHI ,  TSUCHITANI AKIKO

IPC: C09D167/04 ,  C12N9/00 ,  C12N11/08 ,  C12P7/62 ,  G01N33/543 ,  C12N11/00 ,  G01N33/545 ,  G01N33/551

CPC classification number: C12N9/93 ,  C07K2319/23 ,  C09D167/04 ,  C12N11/08 ,  C12P7/625 ,  G01N33/54326 ,  G01N33/54393 ,  G01N2333/21 ,  G01N2333/245

Abstract: There is provided a construct in which at least a part of the magnetic material is coated with polyhydroxyalkanoate (PHA), and a method for producing a construct by immobilizing a PHA synthesizing enzyme on the surface of the magnetic material thereby biosynthesizing a PHA and coating such PHA on the material.

Abstract translation: 提供了其中至少一部分磁性材料涂覆有聚羟基链烷酸酯（PHA）的构造，以及通过将PHA合成酶固定在磁性材料的表面上从而生物合成PHA并涂覆其的制造方法 PHA上的材料。

公开(公告)号：WO2007004600A3

公开(公告)日：2007-06-07

申请号：PCT/JP2006313195

申请日：2006-06-27

Applicant: CANON KK ,  SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI

Inventor： SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI

IPC: G01N33/531 ,  C12N15/62 ,  G01N33/68

CPC classification number: G01N33/531 ,  G01N33/6854

Abstract: It is intended to provide a target substance-capturing body comprising: a base consisting of a soluble protein; and two or more functional domains capable of binding to different target substances.

Abstract translation: 旨在提供一种目标物质捕获体，其包含：由可溶性蛋白质组成的基质; 和能够结合不同目标物质的两个或更多个功能域。

公开(公告)号：WO2007026972A2

公开(公告)日：2007-03-08

申请号：PCT/JP2006317808

申请日：2006-09-01

Applicant: CANON KK ,  IMAMURA TAKESHI ,  SHIOTSUKA HIDENORI ,  BAN KAZUHIRO ,  IBII TAKAHISA

Inventor： IMAMURA TAKESHI ,  SHIOTSUKA HIDENORI ,  BAN KAZUHIRO ,  IBII TAKAHISA

IPC: C07K16/40 ,  C07K16/18 ,  C07K16/44 ,  C07K17/14 ,  G01N33/553

CPC classification number: C07K16/44 ,  B82Y15/00 ,  B82Y30/00 ,  B82Y40/00 ,  C07K16/00 ,  C07K16/40 ,  C07K2317/565 ,  C07K2317/622 ,  C07K2317/626 ,  G01N33/543 ,  G01N33/54366 ,  G01N33/68 ,  G01N33/6845

Abstract: A binding protein molecule, characterized in that it has a first domain having a binding site to an inhibitor of non-specific adsorption in which the domain comprises a part of the variable region of an antibody as the binding site and a second domain having a binding site to a target substance in which the domain comprises a part of the variable region of an antibody as the binding site, wherein the first and second domains are bound via a linker.

Abstract translation: 一种结合蛋白分子，其特征在于它具有第一结构域和第二结构域，所述第一结构域具有与非特异性吸附抑制剂的结合位点，其中所述结构域包含抗体的可变区的一部分作为结合位点，所述第二结构域具有结合 其中所述结构域包含抗体的可变区的一部分作为结合位点，其中所述第一和第二结构域通过接头结合。

公开(公告)号：WO2005095461A3

公开(公告)日：2006-12-14

申请号：PCT/JP2005006815

申请日：2005-03-31

Applicant: CANON KK ,  SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI ,  KUMAGAI IZUMI

Inventor： SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI ,  KUMAGAI IZUMI

IPC: C07K16/44 ,  C12N15/09 ,  C12N15/11 ,  C12N15/63 ,  G01N33/53 ,  G01N33/532

CPC classification number: G01N33/532 ,  C07K16/44 ,  C07K2317/21 ,  C07K2317/56 ,  C07K2317/622 ,  C07K2317/92

Abstract: A protein utilizing an anti-gold antibody and a gold-binding side which is a part of the anti-gold antibody is constructed. This protein is capable of specifically binding to gold. This protein or a complex protein containing such a protein can be used for the detection of a target substance.

Abstract translation: 构建了使用抗金抗体和作为抗金抗体的一部分的金结合侧的蛋白质。 该蛋白质能够特异性结合金。 该蛋白质或含有这种蛋白质的复合蛋白质可用于检测目标物质。

公开(公告)号：CA2611863C

公开(公告)日：2012-08-07

申请号：CA2611863

申请日：2006-06-27

Applicant: CANON KK

Inventor： SHIOTSUKA HIDENORI ,  IMAMURA TAKESHI

IPC: G01N33/531 ,  C12N15/62 ,  G01N33/68

Abstract: It is intended to provide a target substance-capturing body comprising: a base consisting of a soluble protein; and two or more functional domains capable of binding to different target substances.

公开(公告)号：DE602004020351D1

公开(公告)日：2009-05-14

申请号：DE602004020351

申请日：2004-07-02

Applicant: CANON KK

Inventor： HASHIMOTO HIROYUKI ,  KUGE KATSUAKI ,  KOMATSU MANABU ,  NAKAMURA KUMI ,  BAN KAZUHIRO ,  IMAMURA TAKESHI ,  KOBAYASHI SHIN

IPC: G01N33/68 ,  H01J49/04 ,  H01J49/40

公开(公告)号：DE60318968T2

公开(公告)日：2009-02-05

申请号：DE60318968

申请日：2003-02-28

Applicant: CANON KK

Inventor： YANO TETSUYA ,  KENMOKU TAKASHI ,  HONMA TSUTOMU ,  SUGAWA ETSUKO ,  FUKUI TATSUKI ,  IMAMURA TAKESHI

IPC: C08G63/06 ,  C08G63/664 ,  C08G63/682 ,  C08G63/685 ,  C08G63/688 ,  C12P7/62 ,  C12P11/00 ,  C12P17/00 ,  C12R1/38 ,  C12R1/40

Abstract: A method is provided for controlling the molecular weight of a polyhydroxyalkanoate containing at least one of a unit: -ÄOCH((CH2)mR1)CH2C(O)Ü- (m=1-8; R1 is a residue having a ring structure of any of phenyl and thienyl structure), and a unit: -ÄOCH((CH2)kC6H10R2)CH2C(O)Ü- (k=0-8; R2 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen atom, CH3, C2H5, C3H7, CF3, C2F5 or C3F7), wherein a microorganism is cultivated in the presence of a hydroxyl group-containing compound, which is capable of producing the polyhydroxyalkanoate from R3(CH2)qCH2CH2COOH (q=1-8; R3 contains a residue having a ring structure of phenyl or thienyl) or R4C6H10(CH2)rCH2CH2COOH (r=0-8; R4 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen, CH3, C2H5, C3H7, CF3, C2F5, or C3F7).

公开(公告)号：DE60318968D1

公开(公告)日：2008-03-20

申请号：DE60318968

申请日：2003-02-28

Applicant: CANON KK

Inventor： YANO TETSUYA ,  KENMOKU TAKASHI ,  HONMA TSUTOMU ,  SUGAWA ETSUKO ,  FUKUI TATSUKI ,  IMAMURA TAKESHI

IPC: C08G63/06 ,  C08G63/664 ,  C08G63/682 ,  C08G63/685 ,  C08G63/688 ,  C12P7/62 ,  C12P11/00 ,  C12P17/00 ,  C12R1/38 ,  C12R1/40

Abstract: A method is provided for controlling the molecular weight of a polyhydroxyalkanoate containing at least one of a unit: -ÄOCH((CH2)mR1)CH2C(O)Ü- (m=1-8; R1 is a residue having a ring structure of any of phenyl and thienyl structure), and a unit: -ÄOCH((CH2)kC6H10R2)CH2C(O)Ü- (k=0-8; R2 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen atom, CH3, C2H5, C3H7, CF3, C2F5 or C3F7), wherein a microorganism is cultivated in the presence of a hydroxyl group-containing compound, which is capable of producing the polyhydroxyalkanoate from R3(CH2)qCH2CH2COOH (q=1-8; R3 contains a residue having a ring structure of phenyl or thienyl) or R4C6H10(CH2)rCH2CH2COOH (r=0-8; R4 denotes a substituent on the cyclohexyl group including H, CN, NO2, halogen, CH3, C2H5, C3H7, CF3, C2F5, or C3F7).